TWAS
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Neuroticism
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chr18:34,124,783-35,844,220
Best TWAS P=3.71e-09 · Best GWAS P=1.18e-18 conditioned to 6.72e-07
34.2M
34.4M
34.6M
34.8M
35M
35.2M
35.4M
35.6M
35.8M
0
5
10
15
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
The Cancer Genome Atlas
Kidney Renal Papillary Cell Carcinoma
CELF4
0.09
0.01
enet
7
0.02
0.0196
8.47
5.9
3.7e-09
0.69
0.02
0.59
TRUE
1
CommonMind
Brain Pre-frontal Cortex
CELF4
0.05
0.00
blup
509
0.02
0.0036
-0.93
5.2
1.8e-07
0.27
0.09
0.03
TRUE