Best TWAS P=5.42e-12 · Best GWAS P=1.07e-14 conditioned to 5.83e-07
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | TCF4 | 0.06 | 0.00 | enet | 4 | 0.00 | 5.1e-01 | 5.5 | -6.9 | 5.4e-12 | -0.49 | 0.19 | 0.23 | TRUE |
| 2 | The Cancer Genome Atlas | Lung Adenocarcinoma | TCF4 | 0.04 | 0.06 | lasso | 2 | 0.06 | 1.9e-07 | 5.5 | -5.3 | 1.2e-07 | -0.26 | 0.96 | 0.03 | FALSE |