TWAS
hub
About
Usage
Models
Genes
Traits
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Traits
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Neuroticism
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chr2:23,453,834-24,924,438
Best TWAS P=8.41e-08 · Best GWAS P=1.51e-07 conditioned to 0.0248
23.4M
23.6M
23.8M
24M
24.2M
24.4M
24.6M
24.8M
25M
0
2
4
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
The Cancer Genome Atlas
Lung Adenocarcinoma
UBXN2A
0.05
0.00
blup
46
0.01
0.013
-0.6
5.4
8.4e-08
0.67
0.01
0.26
TRUE
1
GTEx
Heart Atrial Appendage
UBXN2A
0.08
0.02
lasso
3
0.02
0.052
4.8
5.2
2.1e-07
0.90
0.03
0.86
FALSE