Best TWAS P=3.67e-09 · Best GWAS P=2.86e-08 conditioned to 0.0327
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Coronary | PLGLB1 | 0.21 | -0.01 | enet | 18 | 0.05 | 6.5e-03 | 5.4 | -5.9 | 3.7e-09 | -0.67 | 0.01 | 0.60 | TRUE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | CHMP3 | 0.17 | 0.12 | enet | 20 | 0.14 | 4.7e-18 | 5.5 | -5.7 | 1.6e-08 | -0.86 | 0.01 | 0.99 | FALSE |
| 3 | The Cancer Genome Atlas | Thyroid Carcinoma | VPS24 | 0.05 | 0.02 | blup | 101 | 0.04 | 1.0e-04 | 5.4 | 5.8 | 5.4e-09 | 0.86 | 0.01 | 0.95 | FALSE |