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Neuroticism
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chr2:86,061,013-87,557,137
Best TWAS P=3.67e-09 · Best GWAS P=2.86e-08 conditioned to 0.0327
86M
86.2M
86.4M
86.6M
86.8M
87M
87.2M
87.4M
87.6M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Artery Coronary
PLGLB1
0.21
-0.01
enet
18
0.05
6.5e-03
5.4
-5.9
3.7e-09
-0.67
0.01
0.60
TRUE
3
The Cancer Genome Atlas
Thyroid Carcinoma
VPS24
0.05
0.02
blup
101
0.04
1.0e-04
5.4
5.8
5.4e-09
0.86
0.01
0.95
FALSE
2
ROSMAP
Brain Pre-frontal Cortex
CHMP3
0.17
0.12
enet
20
0.14
4.7e-18
5.5
-5.7
1.6e-08
-0.86
0.01
0.99
FALSE