[Hub]/) : Traits : Smoking Status : →

chr1:7,715,776-9,571,422

Best TWAS P=3.54e-10 · Best GWAS P=1.38e-08 conditioned to 0.923

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous RERE 0.20 0.23 lasso 2 0.24 1.7e-19 5.6 6.0 2.2e-09 -0.77 0.01 0.99 FALSE
2 GTEx Adipose Subcutaneous RP5-1115A15.1 0.14 0.07 enet 20 0.10 2.6e-08 -5.7 5.6 2.3e-08 -0.88 0.01 0.99 FALSE
3 GTEx Adipose Visceral Omentum RERE 0.22 0.17 lasso 5 0.17 5.2e-09 -5.5 5.6 2.1e-08 -0.90 0.03 0.97 FALSE
4 GTEx Breast Mammary Tissue RERE 0.19 0.08 enet 10 0.14 8.0e-08 5.6 5.3 9.5e-08 -0.71 0.02 0.98 FALSE
5 GTEx Breast Mammary Tissue RP5-1115A15.1 0.10 0.07 lasso 2 0.03 7.0e-03 5.6 5.6 2.1e-08 -0.64 0.01 0.98 FALSE
6 GTEx Cells Transformed fibroblasts RERE 0.12 0.08 lasso 4 0.05 6.0e-05 5.3 5.5 4.8e-08 -0.67 0.02 0.98 FALSE
7 GTEx Esophagus Mucosa RERE 0.13 0.16 lasso 3 0.16 7.2e-11 -5.5 5.5 4.1e-08 -0.98 0.01 0.99 FALSE
8 GTEx Lung RP5-1115A15.1 0.05 0.08 lasso 1 0.07 1.0e-05 -5.7 5.7 1.4e-08 -1.00 0.01 0.98 FALSE
9 GTEx Thyroid RP5-1115A15.1 0.09 0.12 lasso 2 0.09 1.5e-07 -5.7 6.0 1.9e-09 -0.99 0.01 0.99 FALSE
10 GTEx Whole Blood RERE 0.19 0.15 lasso 4 0.13 2.7e-12 -5.5 5.6 1.8e-08 -0.98 0.02 0.98 FALSE
11 METSIM Adipose RERE 0.08 0.12 lasso 17 0.13 1.8e-19 5.5 5.2 2.4e-07 -0.80 0.02 0.98 FALSE
12 ROSMAP Brain Pre-frontal Cortex RERE 0.15 0.15 lasso 7 0.15 1.5e-18 5.6 6.0 1.9e-09 -0.73 0.01 0.99 FALSE
13 YFS Blood RERE 0.09 0.15 lasso 4 0.16 5.7e-49 -5.6 5.9 3.4e-09 -0.98 0.01 0.99 FALSE
14 The Cancer Genome Atlas Breast Invasive Carcinoma RERE 0.02 0.03 lasso 2 0.03 4.7e-07 -5.6 5.7 1.3e-08 -0.98 0.01 0.99 FALSE
15 The Cancer Genome Atlas Pancreatic Adenocarcinoma RERE 0.22 0.04 lasso 10 0.08 4.1e-04 -5.5 6.3 3.5e-10 -0.90 0.02 0.95 TRUE