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chr1:7,715,776-9,571,422

Best TWAS P=3.54e-10 · Best GWAS P=1.38e-08 conditioned to 0.923

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
15	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	RERE	0.22	0.04	lasso	10	0.08	4.1e-04	-5.5	6.3	3.5e-10	-0.90	0.02	0.95	TRUE
9	GTEx	Thyroid	RP5-1115A15.1	0.09	0.12	lasso	2	0.09	1.5e-07	-5.7	6.0	1.9e-09	-0.99	0.01	0.99	FALSE
12	ROSMAP	Brain Pre-frontal Cortex	RERE	0.15	0.15	lasso	7	0.15	1.5e-18	5.6	6.0	1.9e-09	-0.73	0.01	0.99	FALSE
1	GTEx	Adipose Subcutaneous	RERE	0.20	0.23	lasso	2	0.24	1.7e-19	5.6	6.0	2.2e-09	-0.77	0.01	0.99	FALSE
13	YFS	Blood	RERE	0.09	0.15	lasso	4	0.16	5.7e-49	-5.6	5.9	3.4e-09	-0.98	0.01	0.99	FALSE
14	The Cancer Genome Atlas	Breast Invasive Carcinoma	RERE	0.02	0.03	lasso	2	0.03	4.7e-07	-5.6	5.7	1.3e-08	-0.98	0.01	0.99	FALSE
8	GTEx	Lung	RP5-1115A15.1	0.05	0.08	lasso	1	0.07	1.0e-05	-5.7	5.7	1.4e-08	-1.00	0.01	0.98	FALSE
10	GTEx	Whole Blood	RERE	0.19	0.15	lasso	4	0.13	2.7e-12	-5.5	5.6	1.8e-08	-0.98	0.02	0.98	FALSE
3	GTEx	Adipose Visceral Omentum	RERE	0.22	0.17	lasso	5	0.17	5.2e-09	-5.5	5.6	2.1e-08	-0.90	0.03	0.97	FALSE
5	GTEx	Breast Mammary Tissue	RP5-1115A15.1	0.10	0.07	lasso	2	0.03	7.0e-03	5.6	5.6	2.1e-08	-0.64	0.01	0.98	FALSE
2	GTEx	Adipose Subcutaneous	RP5-1115A15.1	0.14	0.07	enet	20	0.10	2.6e-08	-5.7	5.6	2.3e-08	-0.88	0.01	0.99	FALSE
7	GTEx	Esophagus Mucosa	RERE	0.13	0.16	lasso	3	0.16	7.2e-11	-5.5	5.5	4.1e-08	-0.98	0.01	0.99	FALSE
6	GTEx	Cells Transformed fibroblasts	RERE	0.12	0.08	lasso	4	0.05	6.0e-05	5.3	5.5	4.8e-08	-0.67	0.02	0.98	FALSE
4	GTEx	Breast Mammary Tissue	RERE	0.19	0.08	enet	10	0.14	8.0e-08	5.6	5.3	9.5e-08	-0.71	0.02	0.98	FALSE
11	METSIM	Adipose	RERE	0.08	0.12	lasso	17	0.13	1.8e-19	5.5	5.2	2.4e-07	-0.80	0.02	0.98	FALSE