Best TWAS P=3.61e-08 · Best GWAS P=9.65e-09 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 4 | GTEx | Uterus | NPM1 | 0.31 | 0.17 | lasso | 9 | 0.09 | 7.4e-03 | -5.4 | 5.5 | 3.6e-08 | -0.99 | 0.04 | 0.79 | TRUE |
| 6 | The Cancer Genome Atlas | Prostate Adenocarcinoma | RANBP17 | 0.03 | 0.06 | lasso | 4 | 0.05 | 8.1e-06 | -5.4 | 5.5 | 4.5e-08 | -1.00 | 0.05 | 0.95 | FALSE |
| 1 | CommonMind | Brain Pre-frontal Cortex | RANBP17 | 0.10 | 0.14 | lasso | 3 | 0.13 | 1.4e-15 | -5.4 | 5.4 | 5.2e-08 | -0.99 | 0.05 | 0.95 | FALSE |
| 2 | GTEx | Brain Caudate basal ganglia | RANBP17 | 0.26 | 0.19 | lasso | 5 | 0.14 | 9.7e-05 | -5.4 | 5.4 | 6.4e-08 | -0.97 | 0.06 | 0.92 | FALSE |
| 3 | GTEx | Brain Cerebellar Hemisphere | RANBP17 | 0.20 | 0.04 | lasso | 5 | 0.05 | 1.6e-02 | -5.4 | 5.3 | 1.3e-07 | -0.98 | 0.05 | 0.80 | FALSE |
| 5 | METSIM | Adipose | RANBP17 | 0.08 | 0.06 | blup | 710 | 0.06 | 1.5e-09 | -5.4 | 5.2 | 2.0e-07 | -0.89 | 0.05 | 0.95 | FALSE |