Best TWAS P=3.61e-08 · Best GWAS P=4.42e-09 conditioned to 0.00723
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | METSIM | Adipose | CCDC167 | 0.08 | 0.08 | enet | 25 | 0.08 | 4.1e-12 | 4.5 | -5.4 | 7.8e-08 | -0.79 | 0.52 | 0.47 | FALSE |
| 2 | NTR | Blood | C6orf129 | 0.03 | 0.02 | lasso | 6 | 0.02 | 1.2e-07 | 4.9 | -5.5 | 4.0e-08 | -0.78 | 0.41 | 0.59 | FALSE |
| 3 | The Cancer Genome Atlas | Breast Invasive Carcinoma | C6orf129 | 0.02 | 0.03 | enet | 6 | 0.03 | 2.3e-06 | 4.9 | -5.2 | 2.2e-07 | -0.81 | 0.14 | 0.86 | FALSE |
| 4 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | C6orf129 | 0.04 | 0.01 | blup | 65 | 0.02 | 3.5e-03 | 4.4 | -5.5 | 3.6e-08 | -0.73 | 0.08 | 0.72 | TRUE |
| 5 | The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | C6orf129 | 0.07 | 0.02 | blup | 64 | 0.03 | 2.5e-03 | 4.4 | -5.1 | 3.0e-07 | -0.81 | 0.14 | 0.76 | FALSE |