Best TWAS P=1.08e-07 · Best GWAS P=2.45e-07 conditioned to 0.177
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | METSIM | Adipose | CORO1C | 0.07 | 0.07 | lasso | 4 | 0.09 | 3.0e-13 | -4.7 | 5.3 | 1.1e-07 | 0.83 | 0.04 | 0.95 | TRUE |
2 | The Cancer Genome Atlas | Rectum Adenocarcinoma | CORO1C | 0.14 | 0.09 | lasso | 7 | 0.04 | 3.5e-02 | 5.1 | 5.1 | 2.8e-07 | 0.87 | 0.01 | 0.78 | FALSE |