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chr14:103,289,637-105,211,221

Best TWAS P=1.21e-09 · Best GWAS P=2.51e-09 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous PPP1R13B 0.04 0.02 lasso 2 0.01 4.1e-02 5.7 -5.7 1.2e-08 -0.90 0.03 0.89 TRUE
2 GTEx Adrenal Gland CKB 0.18 0.00 enet 16 0.02 6.9e-02 4.2 5.5 4.2e-08 0.40 0.06 0.28 FALSE
3 GTEx Artery Tibial XRCC3 0.06 0.08 lasso 3 0.03 1.4e-03 5.9 6.0 1.9e-09 0.93 0.02 0.98 TRUE
4 GTEx Artery Tibial TDRD9 0.15 0.06 enet 15 0.02 9.7e-03 -4.4 -6.1 1.2e-09 -0.21 0.89 0.04 TRUE
5 GTEx Brain Cortex XRCC3 0.12 0.02 lasso 4 0.01 1.7e-01 5.6 5.3 8.9e-08 0.80 0.04 0.77 TRUE
6 GTEx Brain Nucleus accumbens basal ganglia TDRD9 0.23 0.02 lasso 3 0.05 1.5e-02 5.7 -6.0 1.6e-09 -0.80 0.04 0.63 TRUE
7 GTEx Breast Mammary Tissue KLC1 0.12 0.02 enet 26 0.07 2.9e-04 5.7 5.4 8.6e-08 0.80 0.05 0.95 FALSE
8 GTEx Breast Mammary Tissue TDRD9 0.29 0.00 enet 32 0.11 3.1e-06 -0.9 -5.5 4.2e-08 -0.28 0.07 0.06 FALSE
9 GTEx Cells EBV-transformed lymphocytes PPP1R13B 0.15 0.08 lasso 4 0.07 2.2e-03 5.7 -5.7 1.2e-08 -0.87 0.03 0.93 FALSE
10 GTEx Esophagus Gastroesophageal Junction PPP1R13B 0.09 0.08 lasso 2 0.05 7.9e-03 6.0 -5.9 4.0e-09 -1.00 0.03 0.90 FALSE
11 GTEx Esophagus Muscularis PPP1R13B 0.12 0.07 lasso 5 0.07 3.9e-05 5.7 -5.9 3.8e-09 -0.95 0.03 0.97 FALSE
12 GTEx Skin Not Sun Exposed Suprapubic KLC1 0.11 0.09 lasso 4 0.10 4.1e-06 5.7 5.2 2.1e-07 0.82 0.03 0.96 FALSE
13 GTEx Testis KLC1 0.17 0.17 lasso 2 0.15 4.4e-07 4.2 5.1 3.0e-07 0.89 0.03 0.96 TRUE
14 METSIM Adipose TDRD9 0.08 0.04 lasso 10 0.06 1.9e-09 3.8 -5.5 3.1e-08 -0.55 0.75 0.24 TRUE