Best TWAS P=1.59e-08 · Best GWAS P=3.28e-08 conditioned to 0.0851
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | LINC00899 | 0.17 | 0.04 | lasso | 5 | 0.06 | 1.1e-05 | -5.5 | -5.1 | 2.7e-07 | 0.87 | 0.00 | 0.99 | FALSE |
| 2 | GTEx | Artery Tibial | LINC00899 | 0.30 | 0.08 | enet | 18 | 0.18 | 5.1e-14 | -3.5 | -5.7 | 1.6e-08 | 0.79 | 0.04 | 0.96 | TRUE |
| 3 | GTEx | Cells Transformed fibroblasts | LINC00899 | 0.18 | 0.01 | enet | 13 | 0.06 | 4.9e-05 | -4.5 | -5.4 | 6.2e-08 | 0.77 | 0.03 | 0.96 | FALSE |
| 4 | The Cancer Genome Atlas | Thyroid Carcinoma | LOC100271722 | 0.05 | 0.04 | enet | 8 | 0.09 | 7.5e-09 | -5.1 | -5.4 | 8.5e-08 | 0.85 | 0.01 | 0.99 | FALSE |