Best TWAS P=3.22e-08 · Best GWAS P=9.68e-08 conditioned to 0.285
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Testis | MRAS | 0.20 | 0.14 | lasso | 4 | 0.11 | 1.2e-05 | 5 | -5.3 | 1.2e-07 | -0.92 | 0.02 | 0.97 | FALSE |
2 | The Cancer Genome Atlas | Brain Lower Grade Glioma | MRAS | 0.03 | 0.01 | blup | 49 | 0.01 | 9.6e-03 | 5 | -5.5 | 3.2e-08 | -0.87 | 0.02 | 0.85 | TRUE |
3 | The Cancer Genome Atlas | Soft Tissue Sarcoma | MRAS | 0.04 | 0.03 | blup | 49 | 0.04 | 1.8e-03 | 5 | 5.3 | 1.0e-07 | 0.92 | 0.02 | 0.83 | FALSE |