[Hub]/) : Traits : Type 2 Diabetes (T2D) (2018) : ← →

chr3:49,030,828-50,800,146

Best TWAS P=9.37e-10 · Best GWAS P=2.44e-09 conditioned to 0.0414

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	RNF123	0.14	0.10	blup	324	0.12	4.7e-14	5.0	5.5	2.9e-08	-0.64	0.42	0.57	FALSE
2	GTEx	Artery Aorta	UBA7	0.06	0.02	enet	12	0.01	5.3e-02	4.9	-5.8	7.9e-09	0.65	0.12	0.72	FALSE
3	GTEx	Brain Cerebellar Hemisphere	FAM212A	0.25	0.17	lasso	21	0.20	8.1e-06	-5.0	5.4	5.6e-08	-0.57	0.22	0.55	FALSE
4	GTEx	Brain Cortex	RBM6	0.21	0.25	lasso	4	0.29	8.8e-09	-5.0	-5.9	4.2e-09	0.68	0.18	0.81	FALSE
5	GTEx	Brain Cortex	RNF123	0.23	0.05	enet	33	0.04	2.4e-02	4.7	5.5	4.5e-08	-0.71	0.04	0.84	FALSE
6	GTEx	Brain Nucleus accumbens basal ganglia	RBM6	0.20	0.19	enet	29	0.22	2.0e-06	-5.0	-6.1	9.4e-10	0.76	0.05	0.94	TRUE
7	GTEx	Cells Transformed fibroblasts	RBM6	0.27	0.29	enet	17	0.31	1.3e-23	-5.0	-5.2	2.2e-07	0.45	0.23	0.76	FALSE
8	GTEx	Colon Transverse	RBM6	0.29	0.33	enet	43	0.36	4.6e-18	-5.0	-5.1	2.7e-07	0.45	0.25	0.75	FALSE
9	GTEx	Esophagus Gastroesophageal Junction	RBM6	0.25	0.29	lasso	23	0.30	2.2e-11	-5.1	-5.2	2.3e-07	0.60	0.27	0.73	FALSE
10	GTEx	Esophagus Mucosa	RNF123	0.07	0.03	enet	9	0.04	1.8e-03	4.8	5.2	2.0e-07	-0.63	0.24	0.61	FALSE
11	GTEx	Thyroid	MST1R	0.06	0.06	enet	9	0.05	1.7e-04	4.9	5.7	1.0e-08	-0.71	0.19	0.79	FALSE
12	GTEx	Vagina	RBM6	0.24	0.22	enet	27	0.21	1.5e-05	-5.1	-5.1	3.1e-07	0.49	0.25	0.69	FALSE
13	METSIM	Adipose	RNF123	0.03	0.02	lasso	12	0.02	2.0e-04	4.7	5.5	4.6e-08	-0.80	0.10	0.89	FALSE
14	The Cancer Genome Atlas	Breast Invasive Carcinoma	RBM6	0.03	0.04	blup	79	0.05	9.5e-10	-5.0	-5.1	2.9e-07	0.46	0.06	0.94	FALSE
15	The Cancer Genome Atlas	Breast Invasive Carcinoma	UBA7	0.01	0.01	enet	5	0.01	6.6e-04	4.7	-5.6	2.3e-08	0.83	0.02	0.96	FALSE
16	The Cancer Genome Atlas	Colon Adenocarcinoma	UBA7	0.11	0.06	enet	5	0.05	7.6e-04	4.7	-5.9	3.0e-09	0.83	0.02	0.98	FALSE
17	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	RBM6	0.09	0.11	blup	79	0.11	3.8e-12	-4.9	-5.2	2.7e-07	0.52	0.06	0.94	FALSE
18	The Cancer Genome Atlas	Brain Lower Grade Glioma	MST1R	0.08	0.07	enet	10	0.09	2.6e-10	4.9	5.3	1.2e-07	-0.54	0.02	0.98	FALSE
19	The Cancer Genome Atlas	Brain Lower Grade Glioma	TRAIP	0.02	0.01	enet	8	0.01	3.1e-02	4.0	5.1	2.9e-07	-0.58	0.04	0.12	FALSE
20	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	UBA7	0.02	0.01	blup	30	0.02	5.3e-03	4.8	-5.3	9.0e-08	0.67	0.06	0.35	FALSE
21	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	CAMKV	0.07	0.05	enet	9	0.06	2.3e-03	4.8	5.2	1.5e-07	-0.59	0.03	0.29	FALSE
22	The Cancer Genome Atlas	Testicular Germ Cell Tumors	RBM6	0.16	0.12	blup	79	0.09	4.4e-04	-5.0	-5.8	8.6e-09	0.52	0.05	0.93	FALSE