Best TWAS P=1.61e-07 · Best GWAS P=3.29e-07 conditioned to 0.418
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Breast Mammary Tissue | ZNF517 | 0.12 | 0.03 | enet | 24 | 0.04 | 3.5e-03 | -4.6 | -5.1 | 2.8e-07 | -0.58 | 0.07 | 0.84 | FALSE |
| 2 | GTEx | Heart Atrial Appendage | ZNF251 | 0.09 | 0.06 | lasso | 2 | 0.05 | 3.4e-03 | -4.7 | 5.2 | 2.1e-07 | 0.62 | 0.02 | 0.63 | TRUE |
| 3 | ROSMAP | Brain Pre-frontal Cortex | KIFC2 | 0.12 | 0.10 | enet | 12 | 0.11 | 6.8e-14 | -4.3 | -5.2 | 1.6e-07 | -0.73 | 0.08 | 0.87 | TRUE |