Hub : Genes

ZNF517

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.0960 0.0320 2.0e-10 0.079 0.091 0.088 0.090 0.092 7.3e-10 3.3e-11 7.4e-11 4.8e-11 3.0e-11
2 GTEx Artery Tibial 0.0405 0.0204 5.9e-03 0.036 NA 0.023 NA 0.033 7.2e-04 NA 6.2e-03 NA 1.2e-03
3 GTEx Brain Cerebellar Hemisphere 0.1540 0.0860 4.7e-03 0.142 NA 0.113 NA 0.162 1.7e-04 NA 7.9e-04 NA 5.9e-05
4 GTEx Brain Frontal Cortex BA9 0.1236 0.0628 7.6e-03 -0.011 NA -0.009 NA -0.011 8.4e-01 NA 6.4e-01 NA 8.9e-01
5 GTEx Brain Hypothalamus 0.1770 0.0800 7.3e-03 0.065 NA 0.058 NA 0.033 1.3e-02 NA 1.8e-02 NA 5.7e-02
6 GTEx Breast Mammary Tissue 0.1160 0.0480 5.0e-05 0.035 NA 0.041 NA 0.037 6.6e-03 NA 3.5e-03 NA 5.4e-03
7 GTEx Breast Mammary Tissue (Male) 0.1312 0.0973 6.6e-02 -0.005 NA 0.002 NA -0.012 4.4e-01 NA 2.8e-01 NA 7.8e-01
8 GTEx Breast Mammary Tissue (Female) 0.1031 0.0553 9.6e-03 0.063 NA -0.008 NA 0.005 6.2e-03 NA 6.4e-01 NA 2.2e-01
9 GTEx Cells Transformed fibroblasts 0.1080 0.0390 1.4e-06 0.072 NA 0.057 NA 0.052 4.6e-06 NA 4.6e-05 NA 9.7e-05
10 GTEx Colon Sigmoid 0.1160 0.0530 1.4e-03 0.068 NA 0.028 NA 0.024 2.1e-03 NA 3.6e-02 NA 4.7e-02
11 GTEx Colon Transverse 0.1320 0.0570 1.4e-04 0.041 NA 0.075 NA 0.060 5.0e-03 NA 2.0e-04 NA 8.3e-04
12 GTEx Heart Atrial Appendage 0.3870 0.1160 6.4e-06 0.047 NA 0.149 NA 0.104 3.5e-03 NA 3.2e-07 NA 2.1e-05
13 GTEx Heart Left Ventricle 0.1064 0.0401 6.4e-05 0.102 NA 0.078 NA 0.114 4.4e-06 NA 6.0e-05 NA 1.3e-06
14 GTEx Lung 0.1081 0.0444 1.6e-05 0.080 NA 0.062 NA 0.067 1.0e-06 NA 1.7e-05 NA 7.2e-06
15 GTEx Muscle Skeletal 0.0818 0.0382 3.8e-04 0.021 NA 0.036 NA 0.013 3.4e-03 NA 1.8e-04 NA 1.7e-02
16 GTEx Pituitary 0.1570 0.0670 1.9e-03 0.095 NA 0.075 NA 0.079 2.3e-03 NA 6.1e-03 NA 5.0e-03
17 GTEx Testis 0.2660 0.0690 9.4e-09 0.192 NA 0.198 NA 0.200 6.2e-09 NA 3.4e-09 NA 2.9e-09
18 GTEx Thyroid 0.0450 0.0240 5.2e-03 0.036 NA 0.030 NA 0.030 9.0e-04 NA 2.1e-03 NA 2.2e-03
19 GTEx Whole Blood 0.1310 0.0700 5.4e-03 -0.003 NA -0.002 NA -0.002 8.7e-01 NA 6.4e-01 NA 5.2e-01
20 METSIM Adipose 0.0307 0.0201 2.2e-02 0.004 0.012 0.001 0.011 0.002 7.5e-02 5.7e-03 2.1e-01 7.4e-03 1.2e-01
21 ROSMAP Brain Pre-frontal Cortex 0.1122 0.0355 2.3e-10 0.063 0.091 0.098 0.092 0.080 1.6e-08 8.4e-12 1.6e-12 7.4e-12 1.8e-10
22 TCGA Breast Invasive Carcinoma 0.0357 0.0209 2.2e-03 0.019 0.009 0.008 NA 0.013 6.6e-05 5.2e-03 7.5e-03 NA 8.3e-04
23 TCGA Kidney Renal Clear Cell Carcinoma 0.0451 0.0258 1.6e-05 0.042 0.032 0.030 NA 0.037 1.5e-05 1.4e-04 2.2e-04 NA 4.4e-05
24 TCGA Brain Lower Grade Glioma 0.0578 0.0342 9.1e-08 0.081 0.066 0.054 NA 0.077 1.7e-09 5.2e-08 8.4e-07 NA 3.9e-09
25 TCGA Pheochromocytoma and Paraganglioma 0.1890 0.0840 5.0e-07 0.170 0.191 0.166 NA 0.165 2.8e-07 4.4e-08 3.8e-07 NA 4.1e-07
26 TCGA Prostate Adenocarcinoma 0.0829 0.0426 2.7e-06 0.042 0.058 0.061 NA 0.056 3.3e-05 1.1e-06 5.0e-07 NA 1.6e-06
27 TCGA Thyroid Carcinoma 0.0390 0.0250 2.7e-04 0.031 0.032 0.025 NA 0.029 4.5e-04 3.8e-04 1.5e-03 NA 6.6e-04

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27
Bipolar Disorder (2018) 4.4 7.0 14.2 2.5 3.0 2.6 1.5 2.4 2.5 0.0 3.2 0.0 3.4 1.8 2.6 3.0 2.8 0.5 3.1 -3.4 3.0 0.0 3.5 3.1 0.0 3.4 3.4 3.8 2.4 3.0
Bipolar Disorder or Schizophrenia 3.1 7.6 16.1 2.0 2.8 2.8 1.6 2.0 3.3 2.7 2.8 3.0 3.3 2.3 2.0 2.9 2.7 0.9 3.1 -3.3 2.9 3.2 4.0 2.7 0.0 3.3 3.4 3.5 2.1 2.7
Depressed Affect (Nagel 2018) 0.6 1.2 5.8 -1.1 -1.3 -1.0 -0.0 -0.1 -0.5 0.4 -1.2 -0.9 -1.1 -0.5 -1.6 -1.0 -1.5 -0.5 -1.0 1.0 -1.1 0.1 0.3 -1.6 -1.0 -1.4 -0.9 -0.7 -2.4 -1.6
Depression (Nagel 2018) 0.3 0.4 1.9 -0.7 -0.6 -0.4 0.4 -0.8 0.5 0.4 -0.9 0.1 -0.5 -0.7 -1.4 -0.1 -0.8 0.1 -0.6 0.4 -0.4 -0.2 -0.2 -1.1 -0.5 -0.5 -0.4 -0.4 -1.3 -1.0
Intelligence (Savage-Jansen 2018) 0.6 1.9 25.2 0.6 -0.6 -1.6 -5.0 1.9 -1.5 -1.9 -0.5 -1.4 -0.2 -0.1 1.8 -0.4 -0.9 -0.2 -0.2 0.2 -0.3 0.8 -1.1 0.9 0.4 -0.4 -0.3 0.2 -1.3 -0.8
Neuroticism (Nagel 2018) 0.6 1.5 7.8 -1.3 -1.4 -1.1 0.3 -1.4 -0.1 0.2 -1.2 -0.1 -1.2 -0.5 -1.8 -1.2 -1.6 -0.6 -1.2 1.1 -1.1 -0.2 0.8 -1.6 -0.4 -1.9 -0.9 -0.7 -2.8 -1.5
Schizophrenia (2018) 0.9 1.8 5.6 0.5 1.2 1.5 0.9 0.6 2.2 2.0 1.1 1.7 1.5 1.4 0.5 1.3 1.1 0.8 1.4 -1.4 1.2 1.4 2.4 1.0 0.0 1.5 1.6 1.5 0.7 1.0
Schizophrenia vs Biploar Disorder 0.1 0.2 1.1 -0.2 0.0 0.1 1.0 -1.0 0.2 0.0 -0.3 0.0 -0.2 -0.5 0.0 -0.3 -0.2 -0.9 -0.3 0.3 -0.1 0.0 -0.8 -0.5 0.0 -0.3 -0.2 -0.3 -0.6 -0.3
Worry (Nagel 2018) 0.5 1.0 5.7 -1.1 -1.0 -1.0 0.7 -0.6 -0.6 -1.3 -1.0 -0.0 -0.9 -0.6 -1.6 -0.6 -1.4 -0.7 -0.6 0.8 -0.9 -0.1 1.2 -0.9 0.4 -1.7 -0.5 -0.3 -2.4 -0.9
Alzheimer’s Disease (in mother) 0.8 1.0 2.9 -1.3 -1.2 -1.2 -0.7 -0.3 -0.8 -1.1 -0.8 -1.5 -0.8 -1.1 -0.6 -1.4 -1.1 -0.8 -1.3 0.6 -1.0 0.1 0.7 -0.4 1.4 -1.1 -0.3 -0.1 -1.7 -0.7
Alzheimer’s Disease (in father) 0.8 0.8 2.1 0.3 0.9 0.9 -0.1 0.4 1.3 0.6 0.8 1.4 1.1 0.4 1.0 1.1 0.8 0.6 1.1 -1.1 0.8 1.1 0.7 0.9 0.6 1.3 1.0 1.1 0.2 0.9
Alzheimer’s Disease (including proxy) 0.2 0.3 2.0 -0.3 0.1 0.3 0.0 0.4 0.5 -0.1 0.3 -0.2 0.5 -0.2 0.6 0.0 0.1 -0.3 0.3 -0.6 0.2 1.3 0.7 0.7 1.4 0.4 0.9 0.9 -0.9 0.4
Crohns Disease (2017) 0.2 0.4 3.8 -1.2 -0.2 -0.6 -1.4 -0.2 0.1 0.3 -0.2 -0.3 -0.3 -0.5 0.9 0.1 -0.2 -0.9 -0.3 -0.1 -0.4 0.2 0.4 0.6 2.0 -0.3 -0.3 0.2 0.0 -0.1
Irritable Bowel Disease (IBD) 0.2 0.4 4.3 -0.6 0.0 -0.6 -1.0 -0.0 0.1 -0.6 -0.1 0.3 -0.0 -0.2 1.4 0.2 -0.0 -0.7 0.2 -0.4 -0.5 -0.0 0.8 1.2 2.1 0.1 0.2 0.6 -0.3 0.2
Ulcerative Colitis (UC) 0.2 0.3 1.7 0.1 -0.1 -0.4 -0.2 0.3 0.1 -0.7 0.2 0.7 0.1 -0.1 1.3 0.2 -0.0 -0.3 0.5 -0.4 -0.3 -0.2 0.8 1.1 1.2 0.4 0.4 0.5 -0.5 0.3
Major Depression (MDD) 0.1 0.1 0.4 0.0 0.1 -0.2 0.0 -0.1 0.1 0.0 0.2 0.0 0.2 -0.0 0.0 -0.1 -0.2 0.0 0.4 -0.3 0.2 0.6 0.6 0.0 0.0 -0.0 0.2 0.7 -0.2 0.1
Reaction Time 2.3 4.4 8.3 2.5 2.0 2.4 2.8 1.0 2.9 1.7 2.2 2.8 2.0 2.6 2.3 2.7 2.3 1.1 2.1 -2.1 2.2 0.7 0.5 1.6 1.0 1.8 1.8 1.9 2.5 2.3
Verbal and Numeric Reasoning (VNR) 0.5 1.2 9.2 0.7 -0.0 -0.7 -3.0 2.7 -1.4 -1.7 0.3 -1.7 0.2 -0.1 1.2 0.6 0.1 0.2 0.6 0.0 0.4 1.3 -0.9 0.3 -1.0 0.5 0.1 -0.0 -0.2 -0.3
Breast Cancer 0.1 0.4 2.3 0.3 -0.1 0.1 -0.4 0.0 -0.1 -0.6 0.1 -1.4 -0.0 -0.2 -0.3 -0.3 -0.0 0.7 -0.3 0.5 -0.2 -1.5 0.2 -0.3 -1.3 -0.1 -0.2 -1.1 0.5 0.1
Ovarian Cancer 0.3 0.4 1.7 0.9 0.5 0.9 0.4 1.0 -0.4 0.0 0.9 -0.3 0.5 0.2 1.0 0.6 0.5 1.3 0.4 -0.5 0.7 0.5 -0.8 0.9 0.3 0.3 0.7 0.5 0.1 0.6
Prostate Cancer 0.2 0.3 3.7 0.4 -0.4 0.4 1.9 -0.4 0.5 1.4 0.0 -0.4 -0.1 -0.5 -0.4 -0.2 -0.0 -0.2 -0.3 0.3 0.1 -0.7 -0.1 -0.6 -0.4 -0.0 -0.2 -0.6 0.4 0.1
Age at First Birth 0.5 0.8 5.4 0.4 -0.3 -0.8 -2.3 2.0 -1.6 -2.0 -0.3 -0.9 -0.2 -0.4 0.7 0.0 -0.3 0.3 -0.1 0.0 -0.4 0.8 -0.1 0.5 -0.1 -0.3 0.2 -0.1 -0.8 -0.3
Bipolar Disorder (2011) 3.6 3.5 7.9 2.3 2.1 1.8 0.0 1.9 2.0 0.0 2.2 0.0 2.3 1.7 0.0 2.5 1.7 0.7 2.5 -2.5 2.5 0.0 1.6 2.3 0.0 2.2 2.6 2.8 0.9 1.9
Body Mass Index (BMI) (2010) 0.2 0.2 1.5 -0.2 -0.4 -0.8 -0.2 -0.6 0.3 1.2 -0.4 -0.0 -0.4 -0.2 -0.5 -0.6 -0.5 -0.6 -0.5 0.4 -0.3 -0.4 -0.2 -0.5 0.3 -0.5 -0.5 -0.2 -0.4 -0.4
Coronary Artery Disease (CAD) 0.9 1.1 4.6 -0.8 -1.2 -0.8 -1.0 -1.0 0.1 0.0 -0.4 0.0 -1.1 -0.9 -0.7 -0.7 -1.2 -0.7 -1.0 1.3 -0.8 0.0 -1.3 -1.7 -2.1 -1.1 -1.1 -1.7 -0.5 -1.0
Crohns Disease (2012) 0.2 0.3 1.7 -1.3 -0.7 -0.8 0.0 -0.4 0.1 -0.5 -0.7 -0.3 -0.7 -0.8 0.3 -0.4 -0.8 -0.7 -0.6 0.3 -0.8 -0.3 0.3 -0.1 0.0 -0.4 -0.5 -0.1 -0.7 -0.7
Mean Putamen Volume 0.5 0.5 6.7 0.1 -0.2 -0.8 -1.7 -0.4 -0.8 -2.6 -0.1 -0.8 -0.2 -0.3 0.1 -0.3 -0.2 -0.8 -0.2 0.2 -0.4 -0.2 -0.8 0.2 0.1 -0.4 -0.2 -0.2 -0.2 -0.1
Fasting Glucose 0.2 0.2 1.6 -0.5 -0.2 -0.3 0.3 -0.6 -0.5 -1.0 -0.1 -0.1 -0.1 -0.0 -0.4 -0.9 0.1 -0.4 -0.4 0.3 -0.5 -0.5 1.2 -0.4 -0.6 0.1 0.1 -0.5 0.2 -0.1
HbA1C 6.7 7.4 14.2 -2.2 -3.0 -2.8 -1.5 -2.7 -1.8 -1.9 -2.4 -2.8 -2.8 -1.4 -2.7 -2.8 -3.0 -0.3 -2.8 3.6 -2.5 -3.1 -2.2 -3.3 -3.3 -3.1 -3.0 -3.8 -2.7 -3.3
HDL Cholesterol 1.9 3.1 5.2 1.9 2.0 2.0 1.2 2.1 1.5 1.3 1.8 1.5 2.0 1.5 1.1 2.3 2.0 1.7 2.2 -1.9 1.9 0.9 1.3 1.9 -0.5 2.0 2.0 1.9 2.0 1.9
LDL Cholesterol 0.3 0.4 1.3 -0.2 -0.7 -0.3 -1.2 -0.9 -0.4 -0.9 -0.5 0.5 -0.6 -0.8 0.0 -0.6 -0.8 -0.9 -0.8 0.5 -0.6 -0.3 -1.0 -0.5 0.9 -0.6 -0.8 -0.4 0.4 -0.6
Lupus 0.3 0.5 2.0 0.1 -0.7 -0.4 0.1 0.1 -0.5 0.6 -0.4 -1.1 -0.5 -0.7 -0.8 -0.9 -0.5 -0.6 -0.5 0.8 -0.1 -0.4 -1.3 -1.1 -1.4 -0.6 -0.5 -1.1 -0.2 -0.4
Neuroticism (2016) 0.2 0.3 1.7 -0.2 0.2 0.2 -0.8 -0.8 0.0 -0.5 -0.1 0.7 0.3 -0.6 0.8 0.3 -0.1 -1.3 0.3 -0.5 0.5 1.2 0.3 0.2 0.4 -0.1 0.3 0.8 -0.7 0.1
Primary Biliary Cirrhosis 0.3 0.4 1.2 -1.0 -0.5 -1.1 -0.7 -0.7 -0.2 0.5 -0.4 -0.1 -0.6 -0.9 -0.9 -0.5 -0.5 -0.5 -0.6 0.4 -0.6 -0.8 -0.2 -0.6 0.6 -0.6 -0.7 -0.5 -0.0 -0.3
Rheumatoid Arthritis 1.0 1.4 6.0 -0.3 -0.8 -0.3 0.7 -2.3 0.2 -0.2 -0.7 0.3 -0.9 -0.4 -1.5 -0.9 -0.5 -0.9 -1.1 1.6 -0.7 -1.7 -0.6 -2.1 -2.4 -0.6 -1.1 -2.1 0.3 -0.9
Schizophrenia (2014) 1.6 3.6 8.5 1.0 2.0 2.5 1.5 0.6 2.9 1.9 1.9 0.0 2.1 1.9 0.9 2.3 1.9 0.7 2.1 -2.2 2.0 2.3 2.7 1.5 0.0 2.2 2.3 2.3 1.5 1.7
Triglycerides 2.0 3.3 5.6 -2.2 -2.2 -1.7 -0.9 -2.4 -1.0 -0.7 -2.1 -1.0 -2.1 -1.1 -1.7 -2.3 -2.1 -1.8 -2.2 2.0 -2.1 -1.6 -1.6 -2.1 -0.1 -2.0 -2.0 -1.8 -2.0 -2.0
Type 2 Diabetes (T2D) (2012) 4.9 5.7 10.4 -3.0 -2.8 -2.8 0.0 -3.0 -2.1 0.0 -3.0 0.0 -2.8 -2.6 -1.1 -3.2 -3.0 -2.1 -2.8 2.6 -3.2 0.0 -2.4 -1.9 0.5 -2.7 -2.3 -1.8 -2.9 -2.9
Ulcerative Colitis 0.7 1.0 6.6 0.5 0.9 0.4 -1.2 0.6 0.9 0.0 0.9 0.0 1.0 1.2 0.8 0.7 0.8 0.0 1.2 -1.2 0.4 0.0 2.6 1.6 0.0 1.0 1.3 1.6 -0.1 0.8
Blood Eosinophil Count 0.1 0.6 4.2 0.8 0.2 0.3 -0.6 0.2 1.5 0.0 0.7 0.2 0.7 0.8 0.2 1.1 0.2 -0.6 0.9 -0.5 0.4 1.4 2.0 0.5 -0.3 1.0 1.0 0.7 -0.1 0.4
Blood Platelet Count 0.2 2.9 11.0 1.1 1.9 1.5 1.2 -1.0 3.2 3.3 1.4 3.0 1.5 0.7 0.9 1.3 1.9 1.2 1.5 -1.7 1.6 1.1 2.4 0.9 0.1 1.1 1.6 1.6 1.2 1.6
Blood Red Count 0.1 1.0 8.8 -0.0 -0.2 -0.3 -3.0 1.3 -2.0 -2.4 -0.3 -1.5 -0.3 -0.7 1.1 -0.3 -0.3 0.5 -0.5 0.3 -0.4 -0.7 -0.7 0.1 -0.2 -0.6 -0.5 -0.7 0.6 -0.1
Blood White Count 0.0 0.4 2.6 -0.5 0.0 -0.5 1.0 0.6 -1.1 -0.6 -0.3 0.1 -0.2 -1.5 -0.5 0.0 -0.2 0.3 -0.2 -0.1 -0.6 0.1 1.6 -0.5 -0.1 -0.2 -0.2 0.1 0.0 -0.3
Heel T-Score 0.2 1.9 9.6 1.1 1.2 0.5 -1.6 0.7 -0.2 -1.1 1.2 -0.2 1.3 -0.1 3.1 0.6 1.2 0.7 0.9 -1.6 1.0 0.9 -0.9 2.3 2.4 1.4 1.4 1.9 1.3 1.4
BMI 0.2 1.3 6.4 -0.3 -1.0 -0.6 2.1 -0.3 -1.0 0.0 -0.8 -0.9 -1.0 -0.7 -0.8 -0.7 -0.7 -0.4 -0.8 1.4 -1.1 -1.3 -0.2 -2.0 -2.5 -0.8 -1.3 -1.9 -0.5 -1.1
Height 0.1 1.0 9.3 -0.7 -0.7 0.0 -1.5 1.0 -0.6 -1.0 -0.5 -2.4 -0.6 0.8 -0.2 0.1 -0.5 1.4 -0.6 0.6 -0.4 -0.3 -3.0 -0.0 -0.1 -1.2 -0.4 -0.8 -0.6 -0.4
Waist Hip Ratio (WHR) 0.1 0.5 5.1 -0.8 -0.2 -0.4 -0.7 0.0 -1.2 -0.8 -0.4 0.1 -0.2 -1.5 0.4 -0.2 -0.4 -0.8 -0.4 -0.3 -0.5 0.2 0.3 0.5 2.3 -0.2 -0.2 0.4 -0.1 -0.1
Systolic Blood Pressure 2.1 10.3 18.4 -3.3 -3.8 -3.9 -2.0 -1.6 -4.3 -2.5 -3.3 -3.8 -3.5 -3.1 -1.4 -3.9 -3.6 -4.3 -4.0 3.3 -3.8 -2.8 -2.0 -2.3 -0.2 -3.3 -3.4 -2.9 -3.2 -3.5
Smoking Status 2.6 6.2 14.2 1.8 2.4 2.8 3.8 0.5 3.3 3.1 2.6 3.5 2.7 1.5 0.7 2.7 2.4 0.8 2.5 -2.8 2.8 2.7 3.1 1.7 0.3 2.3 2.9 2.7 1.9 2.7
Allergy or Eczema 0.1 0.3 2.2 0.4 0.5 0.1 -1.5 0.8 0.1 -1.0 0.3 0.5 0.2 0.7 0.7 0.4 0.5 0.1 0.4 -0.4 0.0 0.5 0.2 0.8 0.8 0.3 0.2 0.1 0.1 0.4
Cardiovascular Disease 2.2 7.4 18.0 -3.1 -2.6 -3.8 -3.5 -0.8 -4.2 -2.4 -2.6 -3.3 -2.9 -3.5 0.6 -2.9 -2.9 -3.5 -2.8 2.1 -3.0 -2.1 -1.8 -0.7 1.7 -3.2 -2.8 -1.5 -2.3 -2.5
Hypothyroidism (self reported) 0.9 2.1 5.8 1.4 1.9 1.8 0.6 1.0 1.6 0.1 1.7 1.6 1.6 1.7 -0.5 2.0 1.6 1.2 1.8 -1.4 1.8 0.1 1.6 1.0 -0.8 1.4 1.2 1.1 2.4 1.8
Respiratory disease 0.1 0.2 0.8 0.4 0.5 0.5 0.9 -0.9 0.6 -0.4 0.2 0.8 0.2 0.1 -0.6 0.1 0.3 -0.1 0.2 0.1 -0.2 -0.6 0.8 -0.4 -0.3 0.2 -0.0 -0.4 0.9 0.5
Type 2 Diabetes (T2D) (2018) 6.7 12.6 26.3 -3.6 -3.5 -4.1 -4.7 -1.4 -5.1 -4.3 -3.9 -3.9 -3.7 -3.8 -0.4 -3.8 -3.5 -3.6 -3.9 3.0 -3.9 -3.7 -4.3 -1.9 1.0 -3.8 -3.8 -2.6 -2.9 -3.4
Lung FEV1/FVC ratio 0.4 2.2 5.6 1.9 1.2 1.3 -0.4 1.2 2.3 1.5 1.4 1.4 1.4 2.3 1.5 1.6 1.1 2.4 1.6 -1.3 1.7 0.3 1.8 1.8 -0.3 1.0 1.5 1.2 0.8 1.4
Lung FVC 0.5 2.5 10.9 -0.3 -0.6 0.7 2.9 -3.3 2.5 3.1 -0.4 2.1 -0.8 0.2 -2.6 -0.5 -0.5 -0.8 -1.1 1.1 -0.1 -1.3 0.2 -2.2 -2.2 -1.0 -0.8 -1.5 -0.7 -0.7
Neuroticism 0.8 1.9 7.6 -1.5 -1.5 -1.4 -0.2 -1.3 -1.0 -1.4 -1.5 -0.4 -1.4 -0.6 -1.8 -1.3 -1.9 -0.9 -1.3 1.4 -1.4 -0.8 -0.1 -1.7 -0.4 -2.2 -1.2 -0.8 -2.8 -1.6
Chronotype (morning person) 0.5 1.2 4.9 0.1 0.5 0.0 0.7 -0.1 1.5 1.7 1.1 2.2 0.8 0.1 0.1 0.4 0.4 -0.1 0.4 -1.2 1.0 1.2 1.8 1.0 2.1 0.3 1.0 1.6 0.3 1.2
Hair Pigment 0.3 8.8 13.1 2.5 2.7 3.4 2.8 2.9 2.7 2.7 3.6 2.2 3.3 2.7 3.0 3.2 2.9 -0.2 3.0 -3.3 3.1 2.7 3.6 3.1 1.9 3.5 3.3 3.6 3.1 3.3
Tanning 0.0 0.6 2.5 -1.0 -0.3 0.4 -0.8 -1.3 -0.7 -1.5 -0.4 -1.1 -0.5 -0.2 -1.2 -0.8 -0.6 -0.2 -0.8 0.5 -0.5 -0.2 -1.6 -0.5 -0.8 -0.4 -0.4 -0.7 -0.6 -0.5
Hand grip strength (left) 1.5 3.9 7.5 2.2 1.9 2.1 2.7 0.7 2.4 1.8 2.5 2.7 2.1 2.4 1.1 1.7 2.1 1.7 2.0 -2.0 2.5 1.5 1.6 1.8 0.2 1.6 2.2 2.0 1.5 2.4
Number of treatments/medications taken 0.6 1.2 4.2 -0.5 -0.5 -1.1 -0.9 0.5 -1.9 -2.0 -1.2 -1.2 -0.9 -0.8 -0.7 -0.2 -0.9 -1.7 -0.3 0.9 -1.1 -1.6 -0.9 -1.0 -1.5 -0.7 -1.0 -1.1 -0.1 -0.9
Average weekly spirits intake 1.2 1.5 6.9 1.0 1.4 1.4 2.6 -0.3 0.4 -0.2 1.2 1.8 1.2 1.0 0.8 1.0 1.8 -0.0 1.0 -1.1 1.1 -0.6 -0.1 0.6 0.5 1.1 0.5 0.6 2.5 1.6
Sensitivity / hurt feelings 0.5 0.8 3.1 1.2 -0.1 0.2 1.6 -1.5 1.4 0.5 0.5 0.9 0.1 1.1 -1.3 -0.5 -0.3 1.5 -0.2 0.4 0.4 -1.3 0.6 -1.1 -1.8 -0.5 0.1 -0.6 -0.3 0.2
Frequency of depressed mood in last 2 weeks 0.3 0.5 2.6 0.1 -0.4 0.1 0.2 -1.2 0.9 1.3 -0.7 -0.1 -0.4 -0.4 -0.7 -0.5 -0.9 1.0 -0.5 0.3 -0.3 -0.3 -0.9 -0.7 -0.1 -0.3 -0.3 -0.2 -1.6 -0.8
Hearing difficulty/problems: Yes 0.3 0.5 3.8 -0.3 -0.5 0.1 0.8 -0.8 0.5 -0.1 0.1 -0.0 -0.4 0.4 -0.7 -0.1 -0.2 -1.2 -0.4 0.8 -0.2 -0.0 -0.3 -1.3 -2.0 -0.5 -0.3 -1.2 -0.1 -0.3
Relative age of first facial hair 1.2 2.4 4.8 -1.5 -1.3 -2.0 -1.6 -0.6 -2.1 -1.8 -1.9 -1.2 -1.8 -2.1 -0.2 -1.1 -1.3 -1.1 -1.5 1.3 -2.0 -1.8 -2.0 -1.0 1.3 -2.1 -2.2 -0.9 -0.3 -1.3
Other serious medical condition/disability diagnosed by doctor 1.0 1.2 2.6 -0.8 -1.1 -0.9 -0.3 -0.7 -1.1 -0.8 -1.3 -1.1 -1.3 -0.4 -1.2 -1.1 -1.1 -0.8 -0.9 1.5 -1.1 -0.6 -1.4 -1.4 -1.4 -0.8 -1.3 -1.5 -1.2 -1.6
Ever used hormone-replacement therapy (HRT) 0.5 0.7 3.2 -0.4 -0.7 -1.2 -1.6 -0.7 -0.6 1.0 -0.6 -0.4 -0.8 -0.7 0.4 -1.2 -0.7 -0.6 -0.8 0.5 -0.5 -0.2 -1.8 -0.5 0.1 -1.2 -0.6 -0.2 -0.9 -0.8
Ever had hysterectomy (womb removed) 0.9 1.0 4.0 -0.9 -0.8 -1.5 -2.0 -0.6 -0.5 -0.8 -1.1 -0.3 -1.1 -0.4 -0.5 -0.8 -0.7 -1.5 -0.8 0.8 -1.2 -0.9 -1.1 -0.7 0.2 -1.0 -1.0 -0.8 -1.1 -1.1
Systolic blood pressure, automated reading 1.1 3.1 10.0 -1.8 -1.9 -1.9 -0.3 -0.9 -2.7 -1.9 -1.6 -2.0 -1.7 -1.5 -1.0 -2.0 -1.7 -3.2 -2.2 1.8 -2.1 -1.6 -1.3 -1.7 -0.8 -1.5 -1.7 -1.7 -1.2 -1.7
Eye problems/disorders: Diabetes related eye disease 2.9 3.2 10.0 -1.7 -1.8 -1.8 -2.5 0.2 -2.8 -1.7 -1.8 -2.0 -2.0 -2.1 0.4 -1.5 -2.0 -0.9 -1.8 1.4 -1.9 -1.3 -3.2 -0.5 1.0 -1.8 -1.9 -1.0 -1.7 -1.9
Angina 0.7 0.9 2.7 0.1 0.7 0.4 0.9 1.6 -0.1 0.7 0.9 0.3 1.0 0.5 0.7 1.0 0.8 -0.6 1.0 -1.2 1.0 1.1 1.4 1.2 0.1 1.3 1.0 1.5 1.2 0.8
Medication for hormone replacement therapy 2.1 2.4 5.5 -1.7 -1.6 -2.3 -1.3 -1.8 -1.3 0.3 -1.4 -1.8 -1.6 -2.1 -0.5 -2.1 -1.6 -1.6 -1.9 1.3 -1.3 -0.9 -1.7 -1.2 0.7 -2.1 -1.2 -0.9 -1.8 -1.4
Vitamin and mineral supplements 0.3 0.5 3.4 0.7 0.5 0.1 1.1 -1.1 1.9 1.5 0.8 0.8 0.4 -0.1 0.4 0.3 0.4 0.2 0.1 -0.2 0.5 0.9 -0.1 -0.2 -0.0 0.2 0.5 0.2 0.1 0.4
Supplements: Zinc 0.5 0.6 1.5 -0.6 -1.0 -0.7 0.4 -0.4 -0.6 -0.1 -1.1 0.2 -0.9 0.2 -1.2 -0.7 -0.8 -0.4 -0.7 0.8 -1.0 -0.9 -0.5 -0.9 -0.2 -1.0 -0.8 -0.8 -1.2 -0.9
Medication: Co-codamol 0.5 0.5 3.3 -0.1 -0.2 1.0 1.5 0.0 0.7 0.7 -0.0 0.9 -0.3 0.9 -1.8 0.1 -0.3 1.1 0.2 0.5 0.0 -0.6 0.9 -1.0 -1.1 0.0 -0.3 -0.6 0.0 -0.2
Medication: Metformin 4.1 5.8 11.9 -2.3 -2.5 -2.6 -2.5 -1.1 -3.3 -2.9 -2.6 -2.2 -2.7 -2.1 -0.7 -2.7 -2.4 -2.4 -2.6 2.3 -2.9 -3.5 -2.7 -1.7 -0.0 -2.4 -2.9 -2.3 -1.4 -2.2
Diabetes (father) 0.3 0.4 2.3 -0.1 -0.7 -0.8 -1.5 -0.2 -0.2 0.2 -0.4 -1.2 -0.4 0.2 0.9 -0.6 -0.6 -0.5 -0.5 0.3 -0.8 0.2 -1.1 0.3 0.5 -0.4 -0.2 -0.1 -0.7 -0.5
Diabetes (mother) 0.7 0.9 3.3 0.5 0.7 0.4 1.0 1.4 0.4 1.2 1.1 1.3 0.7 0.7 0.4 0.8 0.5 -0.4 0.8 -1.0 1.4 -0.5 1.8 1.0 0.6 0.5 0.5 1.0 1.7 1.1
Severe depression (siblings) 1.7 1.9 4.5 1.8 1.4 1.5 1.7 0.3 1.3 0.3 1.8 1.6 1.7 1.6 0.7 1.1 1.5 0.3 1.4 -1.4 1.9 2.1 0.6 0.7 -0.4 1.2 2.0 1.4 0.6 1.6
Pack years adult smoking proportion 0.8 1.2 4.6 1.7 0.9 1.0 1.3 2.1 0.2 0.9 0.7 -0.3 0.9 0.6 0.5 1.1 0.9 2.1 1.2 -0.6 1.0 1.4 0.2 0.1 -1.9 1.2 0.9 0.4 -0.0 0.4
Impedance of leg (right) 0.4 2.0 6.4 0.7 1.3 1.3 -0.7 1.8 0.9 0.8 1.0 1.2 1.4 1.2 1.2 1.6 1.2 0.9 1.4 -2.0 1.4 0.5 0.7 2.1 2.5 1.3 1.3 2.1 1.3 1.6
Leg fat-free mass (left) 0.1 0.6 3.9 -0.2 -0.5 0.0 1.8 -0.6 -0.3 0.2 -0.1 -0.8 -0.5 -0.2 -0.6 -0.3 -0.1 -0.2 -0.4 1.0 -0.4 -0.6 -0.6 -1.3 -2.0 -0.4 -0.6 -1.4 -0.1 -0.5
Trunk fat percentage 0.1 0.6 3.8 0.7 0.3 0.6 1.9 1.5 -0.5 0.3 0.4 0.0 0.3 0.4 0.8 0.8 0.6 0.1 0.7 -0.2 0.1 -1.1 0.4 -0.1 -1.7 0.9 -0.0 -0.3 0.9 0.4
Hand grip strength (right) 0.5 1.3 3.3 1.4 0.9 0.9 1.2 0.4 1.7 1.1 1.5 1.6 1.1 1.8 0.6 0.7 0.9 1.0 1.0 -0.9 1.7 1.1 0.9 1.1 -0.0 0.7 1.3 1.1 0.1 1.3
Townsend deprivation index at recruitment 0.1 0.1 0.5 0.0 0.0 0.2 0.5 0.1 0.2 0.6 -0.2 0.0 0.1 -0.6 -0.4 0.2 -0.3 0.7 0.1 -0.3 0.1 0.4 0.2 0.2 0.3 0.0 0.3 0.4 -0.7 -0.1
Current tobacco smoking 0.5 0.9 3.7 0.8 0.4 0.7 1.0 1.4 1.4 1.9 0.7 0.4 0.8 0.3 0.5 1.3 0.4 0.1 1.0 -0.9 1.0 1.8 1.2 0.5 0.0 0.7 1.0 0.9 -0.3 0.6
Average weekly fortified wine intake 3.1 3.7 6.6 -2.4 -2.2 -2.1 -2.4 -1.9 -1.0 -1.2 -1.9 -1.3 -2.3 -0.5 -1.9 -2.1 -2.4 -1.2 -2.2 2.3 -2.1 -0.7 -1.9 -1.8 -0.2 -1.7 -2.2 -2.0 -2.4 -2.6
Maternal smoking around birth 0.4 0.6 4.0 0.6 0.5 0.5 1.8 -0.9 1.4 2.0 0.4 0.9 0.3 0.6 0.2 0.2 0.5 0.6 0.4 -0.2 0.4 0.5 0.2 -0.2 -1.2 0.3 0.0 -0.0 0.7 0.2
Fed-up feelings 1.0 1.9 6.0 -1.2 -1.5 -0.5 0.8 -1.5 -0.5 0.1 -1.3 -0.6 -1.3 -0.7 -2.5 -1.6 -1.4 -0.8 -1.3 1.5 -1.3 -0.5 -0.9 -2.2 -2.1 -1.4 -1.3 -1.5 -1.6 -1.7
Frequency of unenthusiasm / disinterest in last 2 weeks 0.7 0.9 3.6 -0.7 -0.9 0.0 0.8 -1.6 1.0 1.0 -1.1 0.0 -0.7 -0.3 -1.9 -0.4 -1.1 -0.4 -0.7 1.0 -0.5 -0.3 -0.1 -1.7 -0.8 -0.7 -0.6 -1.0 -1.5 -1.1
Relative age voice broke 0.2 0.3 1.5 -0.1 -0.0 -0.4 -0.2 0.4 0.4 1.2 -0.4 0.2 -0.3 0.2 1.1 0.9 0.3 0.3 0.2 0.0 -0.4 -1.2 0.2 0.2 0.6 -0.2 -0.7 0.1 1.0 0.0
Taking other prescription medications 0.9 1.4 6.2 -1.0 -0.9 -1.4 -0.9 -0.4 -1.5 -2.5 -1.2 -1.3 -1.2 -0.7 -1.3 -0.8 -1.3 -1.4 -0.7 1.2 -1.4 -1.0 -0.5 -1.3 -1.0 -1.1 -1.0 -1.1 -1.1 -1.3
Age when periods started (menarche) 0.6 1.4 3.2 -1.6 -1.1 -1.3 -1.7 -1.1 -1.6 -1.8 -1.3 -1.1 -1.1 -1.6 -0.1 -1.3 -1.0 0.0 -1.5 0.7 -1.4 -0.1 -1.5 -0.4 0.9 -1.2 -0.9 -0.7 -1.2 -1.1
Bilateral oophorectomy (both ovaries removed) 3.1 3.6 6.6 -1.6 -2.1 -2.4 -2.6 -1.4 -1.3 -1.4 -2.0 -1.6 -2.1 -1.3 -0.4 -2.4 -2.2 -2.4 -2.2 1.9 -2.2 -1.9 -2.5 -1.5 -0.1 -2.1 -2.1 -1.6 -1.8 -2.0
Heel bone mineral density (BMD) T-score, automated (left) 0.6 1.3 7.0 -1.1 -0.8 -0.2 -2.6 -2.3 0.5 -0.5 -0.6 -0.2 -0.9 -0.1 0.6 -1.0 -0.6 -0.6 -1.3 0.7 -1.2 -1.4 -2.5 -0.2 1.5 -0.3 -1.0 -0.6 -0.1 -0.6
Tinnitus: Yes, but not now, but have in the past 0.7 0.7 3.0 0.9 0.4 0.7 1.1 1.3 0.4 -0.8 0.7 0.4 0.6 1.0 -1.0 1.4 0.5 -0.9 0.9 -0.2 0.6 -0.6 1.7 0.1 -1.3 1.0 0.4 -0.3 1.0 0.7
Qualifications: CSEs or equivalent 0.6 0.8 5.3 -0.4 -0.3 0.2 2.3 -1.8 0.9 1.0 -0.3 0.6 -0.6 -0.6 -1.9 -0.0 -0.4 0.6 -0.5 0.6 -0.4 -1.3 -0.0 -1.0 0.5 -0.6 -0.9 -0.8 0.5 -0.2
Serious illness, injury or assault to yourself 0.3 0.4 2.6 0.1 0.1 0.3 1.2 0.1 0.3 0.5 -0.4 0.3 -0.1 0.4 -0.8 0.2 0.4 0.5 0.3 0.4 -0.0 -1.2 0.5 -1.0 -1.6 0.2 -0.4 -0.7 0.9 -0.2
High blood pressure 2.8 7.8 14.8 -3.1 -3.0 -3.3 -2.2 -1.5 -3.9 -1.9 -2.9 -3.0 -3.1 -3.1 -0.5 -3.2 -3.1 -3.5 -3.3 2.7 -3.3 -2.6 -2.4 -2.1 0.2 -3.0 -3.1 -2.4 -2.5 -2.9
Hayfever, allergic rhinitis or eczema 0.2 0.4 5.8 0.3 0.4 -0.1 -2.4 0.2 0.5 -0.6 0.3 0.5 0.2 0.5 0.5 0.1 0.2 -0.3 0.3 -0.5 0.1 0.9 0.3 0.8 0.6 0.1 0.4 0.3 -0.5 0.3
Multivitamins +/- minerals 0.9 1.2 8.2 -1.0 -0.8 -0.6 -1.8 1.1 -2.6 -2.9 -1.0 -1.2 -0.7 -0.1 -0.5 -0.4 -0.6 -0.9 -0.3 0.5 -0.7 -1.5 -0.5 -0.1 -0.2 -0.5 -0.7 -0.7 -0.6 -0.6
Stomach or abdominal pain in last month 0.4 0.5 1.4 -0.7 -0.5 -1.1 -0.3 0.1 -0.6 0.5 -1.1 -0.5 -0.8 -1.1 0.8 0.2 -0.4 -1.0 -0.0 0.4 -0.8 0.4 -1.1 -0.3 0.3 -0.9 -0.6 -0.3 -1.2 -1.0
Supplements: Glucosamine 1.4 1.8 6.2 -1.1 -1.4 -1.5 -2.2 0.6 -2.5 -1.7 -1.6 -1.8 -1.3 -1.5 0.4 -0.9 -1.2 -1.1 -1.0 1.1 -1.3 -0.9 -1.7 -0.8 0.1 -0.9 -1.3 -0.9 -1.3 -1.4
Diverticular disease/diverticulitis (self-reported) 0.6 0.7 2.1 0.7 1.2 0.0 -0.6 0.9 0.2 0.7 0.5 0.2 0.8 -0.5 0.7 1.1 0.8 1.4 1.2 -1.0 0.7 0.3 0.3 1.4 1.0 0.8 0.4 0.9 1.5 0.8
Medication: Atenolol 2.2 2.8 8.3 -1.7 -1.8 -2.1 0.4 -0.8 -2.8 -1.9 -1.6 -1.4 -1.7 -1.6 -1.4 -1.7 -1.8 -2.9 -1.9 1.7 -1.4 -0.8 -1.3 -1.7 -0.2 -1.6 -1.7 -1.4 -1.3 -1.9
Medication: Levothyroxine sodium 1.3 2.2 8.2 1.5 1.8 1.7 0.9 1.7 0.8 -0.2 1.9 1.2 1.7 0.7 0.7 2.0 1.6 1.0 1.8 -1.6 1.6 0.2 1.2 1.3 0.1 1.7 1.1 1.4 2.9 1.9
Sitting height 0.0 0.3 2.0 -0.3 -0.5 -0.1 -0.5 -0.2 -0.3 -1.4 0.3 -0.6 -0.1 0.6 -0.4 0.1 -0.2 -0.8 -0.5 0.4 0.0 -0.8 -1.4 0.2 0.5 -0.5 -0.2 -0.4 0.6 0.3
Chronic bronchitis/emphysema (father) 0.3 0.3 1.4 -0.7 -0.5 -1.0 0.3 0.7 -1.2 0.0 -0.8 -0.6 -0.6 -0.7 0.1 -0.0 -0.3 0.3 -0.2 0.3 -0.7 -0.1 -0.7 -0.1 0.6 -0.2 -0.7 -0.2 -0.4 -0.6
High blood pressure (mother) 0.1 0.1 0.5 0.1 -0.3 0.0 -0.2 -0.6 0.6 0.4 -0.1 0.4 0.2 0.3 0.7 -0.6 0.1 -0.2 -0.2 -0.1 0.1 -0.0 0.5 0.3 0.4 -0.1 0.3 0.4 -0.7 0.1
Body mass index (BMI) 0.2 0.8 7.4 0.5 -0.3 0.3 2.7 -0.1 -0.2 0.7 0.0 -0.0 -0.3 0.0 -0.5 -0.2 0.0 -0.3 -0.1 0.8 -0.5 -1.0 0.1 -1.4 -2.7 0.1 -0.5 -1.3 0.3 -0.3
Impedance of leg (left) 0.4 1.8 5.3 0.8 1.2 1.1 -0.7 1.9 0.6 0.7 0.8 0.9 1.4 1.1 1.5 1.6 1.2 0.8 1.4 -1.9 1.4 0.8 0.3 2.1 2.3 1.2 1.3 2.1 1.0 1.5
Leg predicted mass (left) 0.1 0.6 4.3 -0.1 -0.4 0.1 1.9 -0.6 -0.1 0.4 -0.0 -0.7 -0.4 -0.0 -0.7 -0.3 -0.1 -0.2 -0.4 1.0 -0.4 -0.5 -0.4 -1.3 -2.1 -0.4 -0.4 -1.4 -0.1 -0.4
Trunk fat mass 0.1 0.6 5.0 0.6 0.0 0.6 2.2 1.0 -0.4 0.5 0.3 -0.2 0.1 0.4 0.3 0.6 0.4 -0.2 0.4 0.2 0.0 -1.1 0.1 -0.5 -2.0 0.6 -0.2 -0.7 0.7 0.2
Waist circumference 0.2 0.7 1.7 -0.6 -0.8 -0.6 1.1 -0.1 -1.0 -0.6 -0.6 -0.7 -0.8 -0.8 -0.5 -0.4 -0.6 -1.0 -0.6 1.0 -1.0 -1.3 0.1 -1.3 -1.3 -0.7 -0.9 -1.3 -0.3 -0.6
Number of incorrect matches in round 0.2 0.3 3.8 -0.1 -0.0 -0.5 -0.5 0.1 -0.5 -0.8 -0.3 -0.5 0.0 -0.2 0.1 0.2 -0.4 -2.0 0.1 -0.2 -0.0 -0.6 0.3 0.0 0.6 -0.1 0.0 0.4 0.1 0.1
Past tobacco smoking 3.3 6.1 14.7 -1.7 -2.5 -3.1 -3.5 0.1 -3.0 -2.2 -2.5 -3.8 -2.7 -2.3 -1.5 -2.1 -2.6 -0.9 -2.6 2.9 -2.8 -2.5 -2.2 -2.2 -0.6 -2.4 -2.9 -2.8 -2.1 -2.8
Alcohol usually taken with meals 0.3 0.4 4.0 -0.1 0.4 0.2 -1.8 -0.5 0.1 -2.0 0.2 -0.1 0.4 1.3 0.0 -0.2 0.2 0.2 0.2 -0.2 0.3 0.7 0.4 0.5 -0.1 0.4 0.5 0.3 -0.4 0.1
Nervous feelings 0.8 1.5 4.9 -0.9 -1.2 -1.4 -0.5 -0.8 -0.8 -1.8 -1.2 -1.4 -1.2 -0.8 -1.3 -0.7 -1.4 -0.9 -0.9 1.3 -1.4 0.1 -0.2 -1.8 -0.6 -2.2 -1.0 -1.1 -2.1 -1.3
Frequency of tenseness / restlessness in last 2 weeks 0.4 0.6 4.8 -0.5 -0.9 -0.7 -0.9 -0.7 0.1 0.4 -1.0 -0.5 -0.6 -0.3 -0.6 -1.0 -1.0 -0.0 -0.8 0.7 -0.9 0.4 -0.6 -0.7 0.1 -0.7 -0.4 -0.2 -2.2 -1.1
Hearing difficulty/problems with background noise 1.0 1.6 5.6 1.7 1.2 1.9 2.4 -0.2 1.7 0.9 1.6 1.2 1.3 1.4 0.4 1.1 1.5 0.9 1.0 -0.8 1.5 0.1 0.8 0.3 -1.3 1.0 1.2 0.3 1.9 1.5
Hair/balding pattern: Pattern 2 0.6 0.8 6.5 0.8 -0.1 0.3 0.7 -0.7 1.4 2.5 0.2 0.1 0.2 0.8 1.4 -0.2 0.3 -0.7 0.1 0.2 0.5 1.4 -1.7 -0.0 -0.9 0.5 0.5 -0.2 -0.8 -0.4
Had menopause 1.5 1.9 6.0 1.0 1.9 1.2 -0.6 1.9 -0.1 -0.3 1.3 0.5 1.4 0.9 2.2 1.8 1.9 0.4 1.8 -1.6 1.3 0.8 -0.3 1.7 0.6 1.5 1.1 1.4 2.5 1.5
Had other major operations 2.1 2.6 7.4 -1.5 -1.9 -1.4 1.2 -2.4 -0.4 0.9 -1.6 -0.8 -1.6 -1.0 -1.2 -2.4 -1.5 -2.2 -1.9 1.8 -1.5 0.5 -1.4 -1.9 -0.7 -1.3 -1.3 -1.5 -2.7 -2.2
Forced vital capacity (FVC) 0.3 1.3 9.2 -1.5 -0.9 0.3 1.1 -3.0 1.7 1.8 -0.5 1.1 -0.8 -0.2 -1.9 -0.8 -0.7 -1.2 -1.4 0.8 -0.2 -0.6 -0.4 -1.3 0.0 -0.8 -0.7 -0.6 -0.9 -0.6
Heel bone mineral density (BMD) T-score, automated (right) 0.4 0.9 9.2 -0.4 -0.2 0.0 -3.0 -2.4 1.4 -0.2 0.0 -0.3 -0.2 0.5 0.9 -0.6 -0.1 0.0 -0.9 0.2 -0.6 -0.7 -1.7 0.2 0.7 0.0 -0.3 -0.2 0.1 -0.1
Ever unenthusiastic/disinterested for a whole week 2.2 2.7 8.0 -0.5 -1.7 -1.2 -1.2 -2.8 0.9 1.3 -1.4 -0.8 -1.7 -0.6 -2.2 -1.9 -1.7 0.6 -1.6 2.1 -1.6 -2.0 -1.0 -2.3 -2.0 -1.9 -1.6 -2.3 -1.8 -1.6
Qualifications: None of the above 0.2 0.5 4.5 0.3 0.0 0.7 2.1 -0.5 1.2 1.6 0.4 0.8 0.3 0.7 -0.1 0.3 -0.1 -0.1 0.2 -0.3 0.5 -0.8 0.7 -0.2 0.1 -0.3 0.3 0.4 0.6 0.6
Financial difficulties in last 2 years 0.6 0.7 6.2 1.0 0.4 1.2 2.5 -0.1 0.7 1.5 0.5 -0.2 0.6 0.2 -0.9 -0.2 0.6 -0.0 0.3 -0.1 0.7 0.4 0.6 -0.5 -2.1 0.8 0.6 -0.4 -0.1 0.3
Mouth/teeth dental problems 1.8 2.8 4.9 -1.5 -1.7 -2.0 -2.0 -1.3 -1.6 -1.0 -2.0 -1.9 -2.0 -1.1 0.0 -1.6 -1.3 -0.7 -1.9 1.9 -2.2 -1.1 -2.0 -1.6 -0.4 -2.0 -2.1 -2.1 -1.4 -2.0
Heart attack 0.4 0.5 2.7 -0.2 -0.4 -1.2 -0.1 -0.3 -0.2 1.6 -0.6 -0.4 -0.2 -0.7 1.2 -0.7 -0.4 -1.4 -0.5 -0.1 -0.4 0.8 -0.9 0.3 0.5 -0.2 -0.2 0.6 -0.6 -0.6
Allergy 0.3 0.8 3.7 0.7 0.7 0.9 1.9 1.5 -0.1 0.4 0.7 0.4 1.0 0.2 0.5 1.2 0.9 0.9 1.0 -0.7 1.2 0.0 0.3 0.5 -0.3 1.1 0.8 0.9 1.2 0.8
Pain all over the body in last month 0.2 0.2 1.9 0.5 0.1 0.1 -0.8 -0.1 0.4 0.7 0.2 0.0 -0.1 0.7 0.4 -0.5 -0.0 1.4 -0.0 0.2 0.3 -0.2 -1.1 -0.1 -0.2 -0.1 0.1 -0.1 -0.8 -0.2
Diabetes (self-reported) 8.1 12.5 25.6 -3.3 -3.5 -3.5 -5.0 -1.2 -4.9 -5.1 -4.0 -3.8 -3.7 -3.1 -0.9 -3.0 -3.6 -3.7 -3.4 3.3 -3.8 -3.3 -4.8 -2.4 -0.1 -3.5 -3.7 -3.1 -3.2 -3.6
Hayfever/allergic rhinitis (self-reported) 0.4 0.6 2.8 -0.8 -0.5 -0.7 -1.7 -0.8 0.2 -1.4 -0.1 -0.2 -0.5 0.2 -1.6 -0.8 -0.7 -1.0 -0.5 0.4 -0.4 -1.2 0.7 -0.4 0.3 -0.7 -0.5 -0.4 0.1 -0.1
Medication: Ramipril 0.5 0.7 2.1 -1.2 -0.4 -0.5 -0.6 -0.8 -1.3 -0.7 -1.4 0.6 -0.9 -1.0 0.6 -0.9 -0.1 -1.2 -0.8 0.4 -1.1 -0.9 -1.2 -0.3 0.5 -0.7 -1.0 -0.4 -0.1 -0.7
Medication: Simvastatin 0.6 0.8 2.9 0.0 -0.2 -0.9 -1.5 1.4 -1.6 -1.3 -0.7 -0.6 -0.6 -0.8 1.4 0.2 -0.4 -1.7 -0.0 0.1 -0.6 -1.1 -1.7 0.5 0.8 -0.9 -0.7 -0.1 0.1 -0.2
Fluid intelligence score 0.5 1.1 11.2 -0.6 -0.6 -1.0 -3.4 1.6 -1.7 -2.5 -0.3 -1.6 -0.4 0.2 0.6 -0.6 -0.7 0.1 -0.2 0.3 -0.4 0.3 -0.8 0.4 0.4 -0.0 -0.5 -0.0 -0.4 -0.7
Illnesses of siblings 0.8 1.2 5.4 -1.6 -1.0 -1.5 -2.3 -0.4 -1.0 -1.9 -1.2 -0.3 -1.0 -1.1 0.4 -0.7 -0.8 -1.0 -1.3 0.6 -1.1 -0.9 -0.9 -0.2 1.4 -1.1 -1.1 -0.2 -0.6 -0.9
Neuroticism score 0.7 1.5 6.6 -0.8 -1.3 -0.9 0.5 -1.3 -0.2 -0.8 -1.2 -0.6 -1.1 -0.1 -2.1 -1.0 -1.6 -0.7 -1.0 1.3 -1.0 0.2 0.1 -2.0 -1.1 -1.7 -0.8 -0.9 -2.6 -1.5
Weight 0.1 0.6 5.0 0.1 -0.4 0.3 2.2 -0.1 -0.3 0.3 0.0 -0.5 -0.3 0.2 -0.5 -0.0 0.1 -0.2 -0.2 0.8 -0.3 -1.0 -0.5 -1.2 -2.2 -0.1 -0.5 -1.3 0.3 -0.2
Impedance of arm (right) 0.8 3.6 10.0 0.9 2.0 1.2 -1.6 1.7 1.1 0.5 1.6 1.3 1.9 0.6 2.6 1.8 1.6 1.6 1.8 -2.7 1.9 1.0 1.3 3.2 3.1 2.0 1.8 3.0 1.9 2.2
Arm fat percentage (right) 0.3 1.0 7.4 1.1 0.8 1.0 2.7 1.1 0.4 1.0 0.9 0.8 0.8 0.4 0.5 0.9 0.9 0.5 1.0 -0.5 0.6 -0.6 1.4 0.0 -1.6 1.2 0.5 0.1 1.2 0.8
Trunk fat-free mass 0.1 0.6 3.7 -0.1 -0.4 0.2 1.9 -1.0 0.1 0.4 0.1 -0.5 -0.3 0.1 -1.1 -0.3 0.0 -0.3 -0.4 0.9 -0.1 -0.3 -1.0 -1.2 -1.7 -0.5 -0.3 -1.4 0.0 -0.2
Hip circumference 0.1 0.4 2.2 -0.4 -0.4 -0.1 1.0 0.1 -0.6 -0.2 -0.0 -0.5 -0.4 -0.2 -0.3 -0.1 -0.1 -0.8 -0.2 0.7 -0.4 -1.5 0.2 -0.8 -1.5 -0.3 -0.6 -1.0 0.5 -0.1
Time employed in main current job 0.4 0.5 3.1 0.8 0.3 0.1 -1.6 0.8 -0.1 -0.5 0.2 -1.1 -0.0 -0.0 -1.0 0.5 0.3 0.8 0.4 0.3 0.6 -0.8 -0.2 -0.4 -1.8 -0.5 0.1 -0.9 0.2 0.3
Alcohol intake versus 10 years previously 0.6 0.9 8.2 -0.4 -0.5 -0.4 2.1 0.7 -0.2 2.9 -0.6 -0.1 -0.4 -2.0 0.2 -0.0 -0.3 -0.5 -0.4 0.2 -0.3 -1.5 0.4 -0.5 0.5 -0.0 -1.0 -0.1 1.5 -0.2
Father’s age at death 0.9 1.2 5.1 -0.7 -1.0 -1.6 -1.0 0.0 -1.5 -2.0 -1.0 -0.9 -1.0 -0.9 0.3 -0.8 -1.0 -2.3 -0.8 1.1 -1.2 0.5 -1.3 -0.7 0.1 -0.8 -0.8 -0.6 -1.6 -1.4
Worrier / anxious feelings 1.6 3.1 10.0 -1.4 -2.0 -1.6 -0.1 -1.9 -1.4 -1.2 -1.7 -1.9 -1.8 -1.3 -2.0 -2.0 -2.1 -1.1 -1.9 2.1 -1.8 0.1 -0.5 -2.2 -0.8 -2.3 -1.4 -1.8 -3.2 -2.1
Frequency of tiredness / lethargy in last 2 weeks 1.6 2.6 5.4 -1.6 -2.0 -1.1 -0.6 -1.3 -1.0 -0.9 -1.9 -0.9 -1.7 -1.0 -2.3 -1.4 -1.9 -1.8 -1.7 2.0 -1.8 -1.4 -0.1 -2.2 -1.7 -1.3 -1.7 -1.8 -2.0 -2.1
Falls in the last year 0.6 0.8 4.3 0.1 -0.4 -0.0 -0.5 -2.1 0.7 -0.3 -0.4 0.0 -0.6 -0.1 -0.9 -0.6 -0.3 0.2 -0.4 1.1 -0.8 -0.3 -1.7 -1.3 -1.9 -0.8 -0.5 -1.4 -0.4 -0.6
Hair/balding pattern: Pattern 3 0.7 1.1 3.1 -1.3 -0.9 -1.0 0.1 -1.0 -0.9 -1.4 -0.8 -1.1 -1.1 -1.3 -1.8 -1.2 -1.1 -0.3 -1.4 0.8 -1.2 -1.7 0.6 -0.8 0.4 -1.2 -1.3 -0.7 -0.2 -0.7
Number of live births 3.4 4.9 12.1 1.6 2.8 2.6 3.3 0.1 2.4 0.1 2.4 3.5 2.4 2.5 0.2 2.0 2.5 1.0 2.3 -2.4 2.3 1.2 3.2 1.6 0.7 2.0 2.3 2.3 2.3 2.5
Forced expiratory volume in 1-second (FEV1) 0.4 1.3 9.9 -1.0 -0.8 0.6 1.2 -3.1 2.1 2.3 -0.2 1.4 -0.6 -0.0 -1.4 -0.8 -0.4 -0.7 -1.1 0.7 -0.1 -0.6 -0.3 -1.2 -0.3 -0.7 -0.6 -0.6 -0.6 -0.4
Pulse rate 0.3 0.4 4.6 0.7 0.6 0.5 0.4 0.6 -0.1 -0.5 -0.0 -0.1 0.2 0.1 -0.6 0.8 0.5 1.1 0.4 -0.0 0.1 -1.2 0.4 -0.3 -2.1 -0.1 -0.0 -0.6 0.8 0.4
Happiness 0.7 0.8 2.2 1.5 0.7 0.9 0.7 0.8 1.1 1.3 0.6 0.7 0.9 0.7 1.1 1.3 0.7 0.5 1.0 -0.9 0.9 0.8 0.7 0.9 1.0 0.9 1.0 1.1 0.3 0.7
Noisy workplace 0.9 1.2 2.4 -1.2 -1.1 -1.3 -0.7 -1.4 -0.4 0.8 -1.2 -0.5 -1.3 -1.3 -0.3 -1.2 -1.1 0.1 -1.2 1.0 -1.1 -1.5 -1.5 -0.9 0.9 -1.4 -1.4 -0.7 -0.7 -1.1
Qualifications: A levels/AS levels or equivalent 0.4 0.8 4.9 0.8 0.9 0.9 -2.2 0.6 0.4 -1.2 0.8 -0.2 0.9 1.0 1.1 0.5 0.8 1.2 0.5 -0.5 0.8 1.2 -0.0 0.8 -0.2 1.4 0.8 0.4 0.4 0.4
Serious illness, injury or assault of a close relative in last 2 years 0.4 0.5 2.7 -0.7 -0.7 -0.6 -1.0 -0.1 -0.6 -1.2 -0.6 0.5 -0.6 -0.0 0.2 -0.5 -0.8 -0.4 -0.5 0.1 -0.6 -1.2 -0.1 0.2 1.6 -0.4 -0.4 0.2 -1.1 -0.3
Mouth/teeth dental problems: Dentures 0.3 0.5 1.6 -0.8 -0.7 -0.5 0.7 -0.3 -1.3 -1.3 -0.5 -0.3 -0.6 -0.9 -0.9 -1.0 -0.9 -0.7 -0.7 0.5 -0.3 -0.5 -0.9 -0.7 -0.4 -0.6 -0.5 -0.3 -0.6 -0.6
Asthma 0.1 0.1 1.6 -0.2 0.1 0.2 0.2 -1.3 0.6 -0.6 0.1 0.2 -0.0 0.6 -0.4 -0.6 0.0 -0.2 -0.1 0.1 -0.4 0.1 0.1 -0.2 0.3 -0.0 0.1 -0.0 -0.2 0.1
Medication: Ibuprofen (e.g. Nurofen) 0.5 0.7 3.2 1.0 0.7 1.1 1.8 1.2 -0.3 -0.2 0.9 0.5 0.8 0.4 -0.4 0.6 0.4 -0.6 0.8 -0.9 0.8 -0.2 0.8 0.6 0.1 0.9 0.8 0.8 1.0 1.0
Medication: Cholesterol lowering 0.9 1.5 5.2 -1.0 -0.9 -1.7 -2.0 0.7 -2.3 -1.3 -1.3 -1.0 -1.1 -1.3 0.8 -0.7 -1.0 -2.0 -0.7 0.5 -1.4 -1.3 -1.1 0.3 1.5 -1.3 -1.1 -0.1 -0.5 -0.7
Depression (self-reported) 1.0 1.2 2.7 -1.0 -1.3 -0.8 -1.3 -0.7 -0.2 -0.0 -1.3 -0.8 -1.2 -0.5 -1.6 -1.1 -1.5 -0.6 -0.8 1.1 -1.0 -1.5 -0.7 -1.1 -0.9 -1.3 -1.1 -1.1 -1.4 -1.2
Medication: Lansoprazole 0.1 0.1 0.4 -0.4 -0.0 -0.3 0.6 0.1 -0.4 -0.1 -0.4 -0.5 -0.3 -0.5 -0.1 -0.0 -0.0 0.2 -0.2 0.2 -0.5 -0.0 -0.7 -0.3 -0.2 -0.3 -0.3 -0.4 0.2 -0.4
Prospective memory result 0.3 0.4 2.5 0.3 -0.4 0.1 -0.1 -1.4 1.6 1.2 0.4 0.4 0.0 0.2 -1.1 -0.7 -0.4 0.1 -0.4 0.3 -0.2 -0.4 0.5 -0.5 -0.6 0.2 -0.0 -0.4 0.1 0.1
Lung cancer (father) 0.4 0.5 4.3 -0.1 -0.4 -0.2 1.0 -0.2 -0.7 0.1 -0.5 0.3 -0.6 -0.5 -0.6 -0.6 -0.3 1.4 -0.4 0.5 -0.8 -2.1 -0.4 -0.4 0.5 0.1 -0.9 -0.7 1.1 -0.4
Illnesses of mother 0.7 0.8 2.6 1.2 1.4 1.0 0.2 1.0 -0.1 -0.6 0.8 0.7 0.9 0.6 1.0 1.6 1.5 0.6 1.2 -0.8 0.8 1.4 -0.5 0.6 -0.2 1.3 0.6 0.4 0.9 0.7
Forced expiratory volume in 1-second (FEV1), Best measure 0.3 0.9 5.3 -0.3 -0.1 0.9 1.5 -2.3 2.2 2.0 0.2 1.1 -0.1 0.5 -1.5 -0.0 0.1 0.2 -0.5 0.4 0.3 -0.5 0.1 -1.0 -0.9 -0.5 -0.1 -0.6 -0.1 0.1
Pulse wave Arterial Stiffness index 2.7 3.1 15.2 0.1 -1.8 -1.3 -2.1 -0.2 -1.1 -0.8 -1.5 -2.4 -1.5 -0.6 -1.7 -1.4 -1.6 0.1 -1.0 2.3 -1.6 -2.0 -2.1 -2.2 -3.9 -1.3 -1.6 -3.1 -1.5 -1.8
Impedance of arm (left) 0.7 3.1 14.8 0.4 1.6 0.8 -2.4 1.9 0.4 -0.1 1.1 1.1 1.5 0.3 2.4 1.6 1.2 1.5 1.5 -2.4 1.4 0.5 1.1 3.2 3.9 1.6 1.4 2.9 1.6 1.8
Arm fat mass (right) 0.2 0.7 8.0 0.7 0.1 0.7 2.8 0.5 -0.1 0.6 0.5 0.4 0.2 0.2 -0.0 0.4 0.4 0.0 0.4 0.2 0.1 -1.0 0.5 -0.7 -2.0 0.6 -0.1 -0.7 0.9 0.3
Trunk predicted mass 0.1 0.6 3.6 -0.1 -0.4 0.2 1.9 -1.1 0.2 0.5 0.1 -0.5 -0.3 0.2 -1.0 -0.3 -0.0 -0.3 -0.4 0.9 -0.1 -0.3 -1.0 -1.2 -1.7 -0.5 -0.3 -1.4 -0.0 -0.2
Standing height 0.0 0.5 3.6 -1.0 -0.5 -0.3 -1.1 -0.1 -0.7 -1.1 -0.3 -1.4 -0.5 0.0 -0.3 0.0 -0.3 -0.1 -0.5 0.5 -0.2 -0.4 -1.9 0.1 0.7 -0.9 -0.4 -0.5 -0.1 -0.1
Length of working week for main job 0.9 1.0 2.3 -1.1 -1.5 -0.9 -0.7 -0.6 -0.3 0.5 -1.2 -1.3 -1.1 -0.6 -1.0 -1.2 -1.1 -0.6 -1.1 1.3 -1.3 -1.4 -1.0 -0.9 -0.1 -0.5 -1.0 -1.1 -0.9 -1.2
Exposure to tobacco smoke at home 0.7 0.8 4.6 -0.2 -0.7 -0.1 0.4 -1.8 0.4 0.1 -0.2 0.1 -0.7 -0.5 -1.7 -1.2 -0.6 0.0 -1.0 0.8 -0.8 -2.2 -0.7 -1.3 -0.7 -0.5 -0.8 -1.1 0.1 -0.4
Breastfed as a baby 0.3 0.3 2.5 0.4 0.0 0.2 -1.2 -0.2 -0.8 -1.4 -0.2 -0.4 -0.1 -0.2 0.7 -0.2 0.2 -0.0 -0.3 0.2 -0.5 -0.5 -1.6 -0.1 -0.1 0.0 -0.1 -0.4 0.3 -0.2
Tense / ‘highly strung’ 1.0 1.6 4.8 -0.9 -1.4 -0.9 0.9 -1.3 -0.0 0.2 -1.0 -0.5 -1.2 -0.2 -2.2 -0.7 -1.3 -1.2 -1.1 1.6 -1.0 -1.6 0.8 -2.1 -1.8 -1.8 -1.0 -1.5 -1.7 -1.1
Seen doctor (GP) for nerves, anxiety, tension or depression 1.0 1.5 3.9 -1.4 -1.4 -1.1 0.6 -1.7 -0.4 0.1 -1.5 0.0 -1.3 -0.8 -1.5 -0.8 -1.2 -2.0 -1.1 1.3 -1.1 -0.7 -1.2 -1.8 -0.3 -1.5 -1.1 -0.9 -1.5 -1.4
Hair/balding pattern: Pattern 4 0.2 0.4 2.3 0.3 -0.1 -0.1 -0.3 1.3 -1.2 -1.4 -0.3 -0.6 -0.1 0.1 -0.2 0.4 0.2 0.3 0.3 0.3 -0.2 -0.3 -0.5 -0.4 -1.5 0.0 -0.2 -0.8 0.1 -0.1
Birth weight of first child 2.8 5.1 8.1 -2.3 -2.8 -2.3 -1.1 -1.9 -1.6 -0.9 -2.5 -2.2 -2.7 -1.0 -2.4 -2.3 -2.8 -1.5 -2.6 2.6 -2.8 -2.8 -1.9 -2.5 -0.3 -2.5 -2.7 -2.4 -2.3 -2.6
Peak expiratory flow (PEF) 0.6 1.3 4.6 -0.9 -1.6 -0.6 -1.1 -2.1 0.2 0.0 -0.5 -0.3 -1.3 -0.3 -1.0 -1.7 -1.2 -0.7 -1.6 1.5 -0.9 -1.6 -0.5 -1.2 -0.9 -1.5 -1.3 -1.5 -0.9 -0.8
Pulse wave reflection index 0.9 1.1 3.3 -0.2 -1.4 -1.0 -1.6 -0.3 -0.2 -0.4 -0.6 -1.5 -0.9 0.4 -0.6 -0.9 -1.2 -0.8 -0.5 1.5 -1.2 -0.8 -0.6 -1.0 -1.8 -0.6 -1.1 -1.7 -0.8 -1.2
Ever highly irritable/argumentative for 2 days 2.7 3.3 5.8 -1.6 -2.0 -1.8 -1.1 -1.8 -1.3 -1.3 -2.2 -1.1 -2.1 -1.6 -2.0 -2.2 -2.3 -0.8 -2.1 2.1 -2.4 -2.1 -1.5 -1.9 0.2 -1.4 -2.2 -1.9 -1.7 -2.1
Loud music exposure frequency 1.3 1.4 8.3 -0.0 -0.9 -0.1 -0.1 -2.0 0.8 0.3 -1.1 -0.7 -0.8 0.9 -1.1 -0.9 -0.6 0.4 -0.8 1.4 -1.0 -0.2 -1.8 -1.8 -2.9 -0.8 -0.8 -1.5 -1.6 -1.4
Qualifications: O levels/GCSEs or equivalent 0.9 1.4 3.5 1.4 1.4 1.1 0.1 1.5 0.4 0.6 1.0 0.6 1.3 0.2 1.8 1.5 1.6 0.9 1.5 -1.3 1.3 1.6 0.8 1.3 0.1 1.9 1.3 1.2 1.0 1.0
Mouth/teeth dental problems: Bleeding gums 0.8 1.1 2.5 1.3 1.2 1.6 1.4 -0.2 1.5 1.0 1.1 1.2 1.1 1.0 -0.6 0.7 1.0 1.4 0.9 -0.9 0.8 -0.2 0.8 0.7 0.0 1.3 0.9 0.7 1.4 1.3
Blood clot in the leg (DVT) 0.7 0.9 1.7 -0.3 -0.8 -1.0 -0.3 -0.6 -0.8 -1.2 -1.3 -1.0 -1.1 -0.2 -1.0 -1.1 -0.9 0.8 -0.8 1.1 -1.1 -1.0 0.4 -1.0 -0.2 -1.3 -1.1 -1.3 -1.0 -1.1
Medication: Paracetamol 1.9 3.1 5.2 2.0 2.0 2.1 1.9 1.0 1.3 -0.4 1.9 1.6 2.1 2.2 0.7 1.9 1.9 -0.0 2.2 -2.0 1.9 2.0 1.5 1.8 0.0 1.9 2.3 1.9 1.6 2.0
Headache pain in last month 0.5 0.9 2.2 1.0 0.6 0.8 1.2 1.5 0.2 0.2 1.0 1.5 0.9 1.0 0.1 1.0 0.6 -1.0 1.1 -1.0 1.1 0.5 0.9 0.9 1.2 0.9 1.0 1.3 1.1 1.0
Medication for cholesterol, blood pressure or diabetes 1.5 2.4 8.8 1.5 1.6 2.0 1.8 -0.6 3.0 2.1 1.8 1.5 1.6 1.4 -0.3 1.4 1.5 1.8 1.4 -1.0 1.8 2.0 1.2 0.2 -1.5 1.7 1.5 0.5 1.0 1.2
Glaucoma (self-reported) 5.4 6.3 12.4 -2.2 -2.7 -3.5 -2.6 -1.8 -2.2 -1.9 -2.9 -3.1 -2.7 -1.7 -0.4 -2.7 -2.3 -3.0 -2.4 2.7 -2.8 -1.0 -3.3 -2.5 -0.5 -2.7 -2.6 -2.3 -2.9 -3.1
Gout (self-reported) 3.0 4.2 9.9 2.5 2.1 2.1 2.0 1.9 2.2 1.7 2.2 1.8 2.2 2.1 0.4 2.4 1.9 3.1 2.3 -2.1 2.2 1.1 2.8 1.8 0.5 1.6 2.4 1.8 1.6 2.2
Hypothyroidism/myxoedema (self-reported) 0.5 0.9 4.5 1.0 1.2 1.1 0.2 0.8 0.8 -0.0 1.1 0.8 1.0 0.5 -0.0 1.5 0.9 0.5 1.2 -0.8 1.1 -0.6 1.1 0.5 -0.7 1.0 0.5 0.6 2.1 1.2
Medication: Amlodipine 0.2 0.3 3.4 0.4 0.1 -0.5 -0.8 0.5 -1.0 -0.5 -0.0 -1.0 -0.1 -0.8 1.8 -0.1 -0.1 0.1 -0.2 0.0 -0.4 -0.2 -0.8 0.7 0.4 0.1 -0.2 -0.1 0.4 0.0
Medication: Ventolin 100micrograms inhaler 1.3 1.6 4.9 -1.1 -0.9 -0.4 0.7 -2.2 -0.5 -0.2 -1.5 -0.9 -1.2 -1.0 -1.8 -1.3 -1.1 -0.7 -1.3 1.5 -1.7 -1.0 -0.3 -2.1 -1.5 -1.0 -1.2 -1.8 -1.1 -1.4
Birth weight 0.3 0.6 5.7 -0.9 -0.3 -0.1 -2.4 -0.8 -0.6 -0.6 -0.2 -0.5 -0.1 -0.4 0.4 -0.6 0.3 -1.6 -0.6 0.1 0.2 0.6 -1.6 -0.1 0.6 0.2 -0.3 0.1 0.3 -0.2
Chronic bronchitis/emphysema (mother) 1.6 1.9 7.5 1.7 1.4 1.7 1.3 1.1 0.9 0.6 1.7 1.3 1.4 1.2 1.0 1.1 1.2 2.7 1.1 -1.6 1.8 0.8 0.0 1.5 0.4 1.5 1.6 1.4 1.3 1.5
High blood pressure (siblings) 0.4 0.5 1.5 0.6 0.9 0.7 0.1 0.5 0.6 0.9 0.8 0.7 0.7 1.2 0.5 0.8 0.8 0.2 1.2 -0.7 0.8 0.9 0.3 0.6 -0.4 1.0 0.8 0.6 0.4 0.6
Forced vital capacity (FVC), Best measure 0.4 1.5 8.9 -1.3 -0.9 0.2 1.1 -3.0 1.6 1.5 -0.7 0.5 -1.0 0.1 -2.4 -0.6 -0.7 -0.5 -1.3 1.2 -0.5 -1.0 -0.9 -1.8 -0.9 -1.2 -0.9 -1.4 -0.8 -0.8
Body fat percentage 0.2 0.8 5.7 0.9 0.4 0.8 2.4 1.5 -0.2 0.7 0.5 0.3 0.4 0.5 0.6 0.9 0.8 0.1 0.8 -0.2 0.2 -1.0 0.7 -0.2 -1.8 0.9 0.1 -0.3 1.0 0.5
Leg fat percentage (right) 0.2 0.8 6.5 1.0 0.2 0.9 2.5 1.6 -0.2 0.7 0.4 0.4 0.3 0.5 0.2 0.9 0.7 -0.0 0.6 -0.1 0.2 -1.1 0.6 -0.5 -1.9 0.7 0.0 -0.5 0.9 0.4
Arm fat-free mass (right) 0.1 0.7 4.7 0.2 -0.4 0.2 2.1 -0.3 -0.4 -0.0 -0.1 -1.0 -0.4 0.3 -0.9 -0.2 0.0 -0.4 -0.3 1.1 -0.4 -0.3 -1.0 -1.4 -2.2 -0.5 -0.4 -1.5 -0.2 -0.4
Exposure to tobacco smoke outside home 1.2 1.6 5.3 -1.1 -1.7 -0.8 -0.7 -0.7 -0.8 -2.0 -0.9 -1.3 -1.3 -0.5 -2.3 -1.4 -1.5 0.2 -1.6 1.3 -1.1 -1.9 -0.5 -1.4 -0.3 -1.4 -1.2 -1.4 -1.2 -1.0
Comparative body size at age 10 0.2 0.5 1.4 -0.7 -0.9 -0.1 0.4 -0.0 -1.0 0.3 -0.8 -0.8 -0.7 -0.6 -0.5 -0.8 -0.5 -0.6 -0.8 0.8 -0.3 0.2 -1.1 -0.8 -0.9 0.1 -0.7 -0.6 -1.1 -1.2
Number of full brothers 1.1 1.4 7.2 1.4 0.8 1.6 2.7 -0.6 2.2 1.8 1.1 1.2 1.1 1.0 0.4 1.2 0.8 0.7 1.0 -0.5 1.1 0.6 0.3 0.1 -1.1 1.2 1.0 0.4 0.9 0.8
Worry too long after embarrassment 0.7 1.1 5.2 -0.2 -0.8 -0.2 -0.0 -1.6 0.8 0.2 -0.6 -0.3 -0.8 0.4 -1.6 -1.1 -1.0 1.3 -0.8 1.3 -0.5 -0.2 0.6 -1.6 -2.3 -1.1 -0.5 -1.2 -1.8 -1.1
Seen a psychiatrist for nerves, anxiety, tension or depression 0.4 0.6 5.0 -0.3 -0.0 0.4 1.7 0.5 1.3 2.2 0.2 0.6 0.1 -0.1 -0.6 1.1 0.3 0.3 0.6 -0.3 0.5 -0.1 1.3 -0.4 -0.4 0.0 0.1 0.4 0.4 0.2
Wheeze or whistling in the chest in last year 0.5 0.8 4.1 -0.5 -1.0 -0.6 1.5 -0.2 -0.4 0.1 -0.9 -1.0 -0.7 -0.3 -0.9 -0.9 -1.1 -2.0 -0.4 0.9 -1.0 -0.2 0.5 -1.2 -0.8 -0.9 -0.4 -0.9 -1.7 -0.8
Number of children fathered 0.2 0.2 1.3 0.6 0.3 0.1 -0.4 -0.9 0.5 -0.1 0.2 0.9 0.2 -0.1 0.8 0.1 0.3 -1.1 0.2 -0.1 0.3 0.3 -1.0 -0.2 -0.5 0.4 0.1 -0.1 0.1 0.1
Reason for reducing amount of alcohol drunk: Health precaution 0.4 0.5 4.3 -0.2 -0.5 -0.2 -1.2 -0.9 0.3 0.5 -0.5 -0.3 -0.6 -0.3 0.1 -0.4 -0.4 -0.5 -0.4 0.7 -0.7 -0.3 -2.1 -0.9 -0.7 -0.4 -0.6 -0.8 -0.7 -0.6
Age at first live birth 0.5 0.8 3.6 -0.3 -0.6 -0.9 -1.5 1.3 -1.9 -1.2 -0.6 -1.1 -0.7 -0.8 1.4 0.1 -0.4 -0.6 -0.2 0.3 -0.6 -0.1 -1.9 0.5 1.3 -0.3 -0.5 -0.2 -0.7 -0.5
Pulse wave peak to peak time 2.4 2.8 16.0 -0.2 1.6 1.2 1.8 0.4 0.7 0.3 1.3 2.2 1.4 0.5 1.7 1.4 1.5 -0.1 0.9 -2.2 1.5 1.7 1.7 2.1 4.0 1.2 1.4 3.0 1.5 1.7
Health satisfaction 0.4 0.5 5.2 1.1 0.3 0.6 2.3 0.3 1.0 1.2 0.3 0.2 0.4 0.4 -0.3 0.5 0.5 -0.1 0.6 0.1 0.2 0.0 0.5 -0.5 -0.9 0.8 0.3 -0.2 0.3 0.1
Shortness of breath walking on level ground 0.8 0.9 4.4 0.6 -0.1 0.7 1.7 -1.1 1.2 2.1 -0.4 0.7 -0.3 0.8 -0.9 -0.1 -0.1 1.9 0.0 0.6 -0.4 -0.6 -1.3 -1.0 -1.8 -0.0 -0.4 -0.9 0.1 -0.5
Qualifications: College or University degree 0.4 1.2 14.8 -0.2 -0.4 -1.0 -3.8 1.5 -1.2 -1.5 -0.7 -1.4 -0.5 -0.3 1.2 -0.1 -0.6 1.5 -0.4 0.2 -0.6 0.1 -0.4 0.6 1.1 -0.2 -0.3 0.1 -1.2 -0.6
Eye problems/disorders: None of the above 0.7 0.8 5.3 0.4 0.3 1.5 0.7 -1.3 2.3 0.6 0.9 1.2 0.8 1.0 -1.0 0.2 0.3 0.7 0.4 -0.4 0.7 0.9 1.6 0.0 -0.9 0.8 0.9 0.3 0.2 0.6
Mouth/teeth dental problems: Loose teeth 2.7 3.2 6.0 1.4 2.1 1.9 1.5 1.2 1.8 1.9 1.9 1.5 2.2 1.0 0.6 2.4 1.9 0.6 2.2 -2.0 2.4 1.1 2.5 1.5 -0.8 2.0 2.1 1.8 1.6 2.1
Emphysema/chronic bronchitis 0.4 0.5 3.1 0.6 -0.1 1.0 0.4 -0.7 1.4 1.8 0.2 0.4 0.3 0.2 -1.1 -0.0 -0.0 0.3 -0.0 0.3 0.4 0.1 0.0 -0.8 -1.5 0.3 0.3 -0.7 -0.0 0.1
Medication for pain relief, constipation, heartburn 0.4 0.7 2.0 -0.7 -0.8 -0.7 -0.7 -1.2 -0.1 -0.1 -0.8 -0.3 -0.9 -0.7 -0.5 -1.0 -0.6 0.9 -1.1 1.0 -0.8 -0.2 -0.6 -1.0 -0.2 -1.0 -0.8 -1.1 -1.4 -1.0
Neck or shoulder pain in last month 1.0 1.5 4.2 -1.1 -1.8 -1.1 -0.5 0.1 -1.0 -0.3 -1.4 -2.0 -1.2 -0.8 -1.2 -1.0 -1.8 -1.8 -1.0 1.3 -1.4 0.1 -0.3 -1.0 -0.9 -0.9 -0.8 -1.4 -2.1 -1.4
Medication: Blood pressure 0.9 1.5 4.6 -1.2 -1.5 -1.6 -0.7 0.5 -2.1 -1.3 -1.3 -0.9 -1.5 -0.8 0.3 -0.7 -1.2 -1.8 -1.2 1.0 -1.3 -2.0 -1.0 -0.5 0.7 -1.3 -1.5 -0.8 -0.8 -1.1
Angina (self-reported) 0.8 1.1 2.5 0.2 0.8 0.5 1.1 1.6 0.2 0.7 1.0 0.5 1.1 0.8 0.8 1.2 0.9 -0.7 1.1 -1.2 1.2 1.2 1.5 1.3 0.1 1.5 1.1 1.6 1.4 0.9
Migraine (self-reported) 0.6 0.7 4.3 0.7 0.8 1.3 1.5 -0.6 0.8 0.2 0.9 2.1 0.7 0.4 -0.4 0.3 0.8 -1.2 0.3 -0.5 0.9 0.3 -0.1 -0.2 -0.6 0.8 0.5 0.5 0.9 0.7
Medication: Ibuprofen 0.5 0.6 2.3 0.7 0.7 0.9 1.5 1.0 -0.1 -0.4 0.7 0.6 0.8 0.8 -0.8 0.8 0.4 -1.0 0.7 -0.8 0.7 -0.1 1.0 0.5 0.2 0.8 0.6 0.8 1.0 0.9
Medication: Allopurinol 0.6 0.8 5.4 0.6 0.6 1.2 1.3 0.4 1.3 1.0 0.7 0.4 0.8 1.3 -1.2 0.5 0.4 2.3 0.7 -0.6 0.7 0.6 1.5 0.1 -0.3 0.5 1.1 0.5 -0.3 0.6
Medication: Omeprazole 0.9 1.0 5.1 -0.4 -0.7 -0.6 -0.1 -1.1 -0.5 -0.3 -0.9 -0.3 -1.1 0.2 -0.7 -0.6 -0.6 -1.0 -0.5 1.3 -1.0 -1.3 -1.2 -1.5 -2.3 -1.4 -1.1 -1.6 -0.8 -0.9
Medication: Seretide 50 evohaler 0.6 0.7 3.2 1.2 0.8 1.4 0.8 -0.8 1.5 1.1 0.7 0.2 0.4 1.2 -0.1 0.1 0.6 1.8 0.5 -0.2 0.3 -1.2 0.3 -0.1 -1.1 0.2 0.5 -0.3 0.6 0.8
Mean time to correctly identify matches 1.1 2.0 5.6 2.1 1.4 1.2 1.9 0.8 2.0 0.8 1.3 1.8 1.2 2.4 2.1 2.0 1.7 0.6 1.6 -1.2 1.3 0.0 -0.5 0.8 0.1 1.0 0.9 0.8 2.0 1.4
Heart disease (mother) 0.2 0.2 1.5 -0.6 -0.3 -0.5 1.0 -0.2 -0.1 0.8 0.1 0.3 -0.1 -0.6 0.1 -0.4 -0.5 -0.6 -0.4 -0.1 -0.2 -0.3 1.2 0.1 0.3 -0.4 -0.1 0.4 0.4 0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.8 0.9 4.7 1.0 0.7 0.8 0.3 -1.0 2.2 0.5 1.1 1.6 1.0 1.6 0.5 0.7 0.5 -0.0 1.0 -0.7 0.7 1.2 1.0 0.5 -1.1 0.8 1.1 0.7 0.2 0.7
Whole body fat mass 0.1 0.6 6.2 0.6 -0.0 0.6 2.5 1.0 -0.4 0.4 0.3 -0.1 0.0 0.3 0.0 0.5 0.4 -0.1 0.3 0.3 -0.0 -1.2 0.3 -0.7 -2.0 0.4 -0.2 -0.8 0.7 0.1
Leg fat mass (right) 0.2 0.8 7.7 0.9 0.0 0.8 2.8 1.1 -0.3 0.6 0.3 -0.0 0.1 0.5 -0.1 0.5 0.5 -0.2 0.4 0.3 0.0 -1.1 0.1 -0.9 -2.5 0.5 -0.1 -1.0 0.7 0.2
Arm predicted mass (right) 0.1 0.7 4.1 0.2 -0.4 0.1 2.0 -0.3 -0.5 -0.3 -0.1 -0.9 -0.4 0.3 -0.8 -0.2 0.0 -0.6 -0.3 1.1 -0.4 -0.4 -1.0 -1.3 -2.0 -0.5 -0.5 -1.5 -0.1 -0.4
Pulse rate, automated reading 0.2 0.6 4.1 0.5 0.4 -0.1 -0.9 2.0 -0.5 0.8 -0.6 -1.1 0.1 -0.3 1.4 1.1 0.3 1.8 0.8 -0.4 -0.1 0.0 -0.8 0.5 0.1 -0.5 0.1 0.2 -0.0 0.0
Alcohol intake frequency. 1.1 2.5 7.9 1.5 1.6 2.0 1.3 1.4 1.9 2.0 1.8 1.6 1.8 1.2 -0.1 1.5 1.4 -0.2 1.7 -1.7 1.9 1.2 2.8 1.2 -0.1 1.6 1.7 1.7 1.6 1.8
Comparative height size at age 10 0.2 1.4 3.8 0.7 1.4 1.3 -0.1 0.9 1.0 -0.5 1.4 1.1 1.4 1.5 0.8 1.9 1.5 0.2 1.4 -1.3 1.5 1.2 -0.1 1.2 0.3 0.8 1.4 1.0 1.1 1.6
Number of full sisters 1.9 2.3 7.2 2.1 1.7 2.0 2.7 0.7 2.1 1.5 1.6 1.6 1.7 1.8 0.4 1.5 1.5 0.2 1.5 -1.3 1.7 1.5 0.6 0.6 -1.2 1.7 1.5 1.0 1.2 1.4
Suffer from ‘nerves’ 0.6 0.9 3.6 -1.0 -1.1 -0.9 0.8 -0.1 -0.6 -1.1 -1.0 0.3 -0.9 -0.2 -1.0 -0.8 -1.5 -0.7 -0.6 0.6 -0.8 -0.9 1.0 -0.6 1.6 -1.4 -0.6 0.3 -1.9 -0.7
Overall health rating 0.3 0.6 3.2 0.7 0.1 1.2 1.7 0.7 0.9 1.8 0.5 0.5 0.4 0.7 -0.2 0.5 0.2 0.3 0.6 0.0 0.3 -0.2 1.6 -0.2 -0.9 0.6 0.3 -0.2 0.5 0.3
Chest pain or discomfort 0.1 0.1 1.7 -0.0 -0.3 -0.0 0.0 0.5 -0.3 0.1 0.1 -0.3 -0.0 0.4 0.4 -0.1 -0.1 -1.3 0.1 0.1 -0.1 0.3 -0.9 -0.0 0.1 0.0 -0.1 0.2 0.0 -0.1
Had major operations 0.4 0.5 3.5 -0.3 -0.0 0.4 1.9 -0.7 0.9 1.0 -0.1 0.6 -0.2 0.0 -1.6 -0.1 -0.5 1.4 -0.1 0.2 -0.0 -0.7 0.6 -0.7 -0.7 0.2 -0.1 -0.4 -0.6 -0.3
Age at last live birth 0.8 1.2 3.9 -1.1 -1.1 -1.1 -0.6 0.1 -1.6 -1.6 -1.3 -1.1 -1.2 -0.8 0.0 -0.5 -0.9 -1.6 -0.8 1.0 -1.2 -0.6 -2.0 -0.8 0.6 -0.9 -1.0 -0.8 -1.3 -1.2
Family relationship satisfaction 0.3 0.4 2.6 -0.1 -0.6 0.4 0.9 -0.7 0.8 0.1 -0.3 0.8 -0.3 1.0 -0.8 -0.0 -0.4 -0.3 -0.0 0.4 -0.6 -1.6 -0.1 -0.6 -0.3 -0.1 -0.5 -0.6 -0.0 -0.2
Leg pain on walking 0.2 0.3 2.8 -0.0 -0.0 0.2 1.0 -0.9 0.6 0.4 0.1 0.7 -0.1 0.0 -1.7 -0.2 -0.1 0.3 -0.0 0.4 -0.2 -0.6 0.7 -0.7 -0.8 0.1 -0.2 -0.4 0.3 -0.1
Qualifications: NVQ or HND or HNC or equivalent 0.8 0.9 9.0 0.7 0.5 0.7 3.0 -1.5 1.2 1.4 0.4 1.4 0.3 -0.0 -1.5 0.1 0.8 0.5 0.0 0.1 0.3 0.1 1.1 -0.8 -0.8 -0.1 0.1 -0.5 0.6 0.5
Commuting to job workplace: Car/motor vehicle 0.4 0.4 2.3 0.8 0.2 0.7 0.9 0.0 1.5 1.2 0.4 0.6 0.3 1.3 0.1 0.6 0.6 1.0 0.5 -0.2 -0.1 -0.3 0.1 0.1 -0.3 0.4 0.1 -0.0 1.1 0.5
Illness, injury, bereavement, stress in last 2 years 0.4 0.5 1.8 -1.1 -0.6 -0.7 -1.3 -1.2 -0.4 -0.8 -0.5 -0.2 -0.7 -0.2 -0.6 -0.9 -0.4 -0.1 -0.9 0.6 -1.0 0.5 -0.5 -0.2 0.9 -0.9 -0.7 -0.5 -0.6 -0.6
Medication: Aspirin 0.2 0.3 1.3 0.0 0.4 0.1 0.1 0.7 0.1 0.1 0.5 0.6 0.5 0.3 0.6 0.5 0.2 0.1 0.4 -0.6 0.3 -0.7 0.8 0.9 0.1 0.2 0.3 0.5 1.1 0.7
Supplements: Vitamin C 0.4 0.5 1.5 -0.1 -0.5 -0.5 -0.8 0.1 -0.8 -0.0 -0.9 -1.1 -0.7 0.1 -0.4 -1.1 -0.4 1.1 -0.7 0.5 -1.0 -0.8 -1.2 -0.2 0.4 -0.5 -0.7 -0.6 -0.3 -0.7
Knee pain experienced in last month 1.0 1.5 6.8 0.9 1.0 1.4 2.6 0.8 1.1 0.0 1.2 0.7 1.2 1.9 -0.6 1.3 1.3 -0.5 1.1 -0.8 1.0 0.9 2.5 0.3 -1.3 1.2 1.1 0.4 1.0 1.1
Hypertension (Self-reported) 2.9 8.1 15.7 -2.8 -3.1 -3.4 -2.8 -1.6 -3.6 -2.0 -2.8 -3.2 -3.1 -2.9 -0.3 -3.2 -3.2 -4.0 -3.2 2.9 -3.3 -2.3 -2.6 -2.2 -0.3 -3.1 -3.1 -2.6 -2.8 -3.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.9 1.1 3.0 -0.9 -1.1 -0.9 0.7 -0.8 -0.9 -0.6 -1.0 -0.8 -1.2 -0.3 -1.4 -0.6 -1.0 -0.5 -0.8 1.3 -1.1 -0.8 -1.4 -1.5 -1.0 -1.7 -1.1 -1.5 -1.1 -1.0
Illnesses of father: Heart disease 0.4 0.6 3.4 0.0 0.3 0.8 -1.1 -0.4 1.7 1.8 0.4 0.1 0.5 1.5 0.3 0.2 0.4 -0.9 0.3 -0.3 1.1 0.6 0.3 0.1 -1.0 0.3 0.7 0.5 -0.1 0.3
Illnesses of siblings: Diabetes 0.6 0.7 2.1 1.5 0.8 1.3 0.8 0.9 0.5 1.1 1.2 -0.4 0.8 0.5 0.6 0.7 0.9 1.2 1.1 -0.4 1.0 0.5 0.4 0.7 -0.4 0.7 0.7 -0.0 1.1 1.0
Smoking status: Previous 2.9 4.3 11.2 1.3 2.2 2.6 3.2 -0.7 2.3 1.5 2.1 3.4 2.3 2.1 1.3 1.4 2.4 0.2 2.1 -2.4 2.3 2.0 1.6 1.6 0.2 1.9 2.4 2.3 2.1 2.3
Forced expiratory volume in 1-second (FEV1), predicted 0.4 0.9 2.9 -1.7 -1.2 -1.2 -0.0 -0.9 -0.4 0.9 -0.8 -0.1 -1.0 -1.2 -1.2 -1.0 -0.9 -1.1 -1.0 0.8 -0.8 -1.0 0.0 -0.5 1.6 -1.0 -1.0 -0.4 -0.4 -0.6
Whole body fat-free mass 0.1 0.6 4.1 0.0 -0.3 0.2 2.0 -0.8 0.2 0.5 0.1 -0.6 -0.3 0.2 -0.8 -0.2 0.1 -0.1 -0.3 1.0 -0.1 -0.2 -0.8 -1.3 -2.0 -0.4 -0.3 -1.4 -0.1 -0.3
Leg fat-free mass (right) 0.1 0.6 4.3 -0.1 -0.5 -0.0 1.7 -0.7 -0.2 0.2 -0.2 -0.9 -0.5 -0.0 -0.5 -0.3 -0.1 -0.1 -0.4 1.1 -0.4 -0.3 -0.7 -1.2 -2.1 -0.5 -0.5 -1.4 -0.3 -0.5
Arm fat percentage (left) 0.2 0.7 5.3 0.9 0.5 0.8 2.3 1.1 0.1 0.9 0.6 0.6 0.5 0.2 0.5 0.7 0.7 0.3 0.8 -0.3 0.3 -0.8 1.1 -0.1 -1.4 1.0 0.2 -0.0 1.0 0.5
Average weekly red wine intake 1.7 2.5 9.6 -1.0 -1.6 -0.9 -2.5 -1.7 -0.5 -1.7 -1.1 -1.8 -1.3 0.2 -1.1 -1.8 -1.5 -0.9 -1.4 1.8 -1.4 -0.7 -2.0 -1.6 -3.1 -1.0 -0.9 -1.9 -2.2 -1.8
Handedness (chirality/laterality): Left-handed 2.9 3.4 8.4 2.7 2.0 2.2 2.6 0.3 2.9 2.0 2.0 2.3 1.9 2.1 0.5 1.5 2.2 2.3 1.8 -1.4 1.8 0.5 1.2 0.9 -1.3 1.6 2.1 0.9 1.6 2.1
Mood swings 0.7 1.2 6.4 -0.5 -1.4 -0.3 0.5 -0.4 -0.6 -0.7 -1.2 -0.8 -1.0 0.1 -1.7 -0.8 -1.4 -0.6 -1.1 1.3 -1.0 -0.2 -0.5 -1.7 -0.9 -1.1 -0.7 -0.9 -2.5 -1.6
Loneliness, isolation 1.1 1.5 4.9 -1.5 -1.4 -1.3 -0.8 -0.9 -0.9 0.3 -1.5 -1.1 -1.2 -1.5 -0.9 -1.4 -1.8 -1.2 -1.2 0.9 -1.2 0.1 -1.9 -1.1 0.5 -1.0 -1.0 -0.4 -2.2 -1.6
Long-standing illness, disability or infirmity 0.5 0.7 2.6 -0.6 -0.6 -0.6 -0.1 -0.7 -0.3 0.1 -1.0 -0.6 -0.8 -0.2 -0.9 -0.5 -0.7 -1.4 -0.4 0.9 -0.9 -0.0 -1.1 -1.3 -1.6 -0.5 -0.7 -1.0 -1.2 -1.1
Ever had bowel cancer screening 0.6 0.7 4.5 -0.4 -0.4 -0.8 -0.8 1.3 -2.1 -1.3 -0.5 -1.5 -0.6 -1.1 0.5 -0.6 -0.5 -0.4 -0.6 0.4 -0.7 -1.1 -1.0 0.1 0.6 -0.3 -0.9 -0.6 0.5 -0.4
Diabetes diagnosed by doctor 7.9 12.9 27.5 -3.2 -3.5 -3.9 -4.8 -1.2 -5.2 -4.8 -4.0 -4.0 -3.8 -3.3 -0.6 -3.4 -3.6 -4.0 -3.6 3.2 -4.0 -3.3 -4.8 -2.2 0.2 -3.8 -3.8 -2.9 -3.2 -3.6
Ever had stillbirth, spontaneous miscarriage or termination 0.3 0.3 2.1 -0.0 0.1 0.7 1.4 -0.6 0.7 1.5 0.2 0.1 0.2 -0.3 -0.3 0.0 0.1 0.8 0.1 -0.1 0.0 0.5 0.3 0.0 -0.7 0.0 0.2 -0.1 0.1 0.3
Friendships satisfaction 0.1 0.1 0.7 0.8 -0.4 -0.5 0.4 0.6 -0.1 -0.1 0.1 0.2 0.0 0.0 -0.1 0.1 -0.3 -0.4 0.2 0.1 0.1 -0.3 0.4 -0.3 -0.5 -0.1 0.2 -0.1 -0.6 -0.1
Qualifications: nursing, teaching 0.4 0.6 3.6 -0.4 -0.7 -0.9 -1.4 -0.1 -1.0 -1.9 -0.3 -0.3 -0.6 -0.5 0.1 -0.8 -0.7 -1.7 -0.5 0.6 -0.8 -0.1 0.0 -0.3 -0.0 -0.2 -0.6 -0.6 -0.4 -0.6
Commuting to job workplace: Walk 2.2 2.4 7.7 0.6 2.1 1.7 -0.4 1.7 0.6 -0.5 1.5 0.6 1.9 1.1 1.7 2.0 1.8 0.3 1.7 -1.8 1.7 2.8 1.6 1.4 -0.3 1.9 1.9 2.0 1.2 1.2
Eye problems/disorders: Cataract 1.5 1.8 4.4 1.3 1.4 1.0 2.0 1.3 0.1 0.9 1.4 1.7 1.4 0.8 1.4 1.3 1.6 -0.2 1.3 -1.5 1.4 0.7 0.8 1.3 1.3 1.2 1.2 1.5 2.1 1.7
Mouth/teeth dental problems: Mouth ulcers 1.4 2.1 5.6 1.5 1.2 1.6 1.1 1.6 1.3 1.3 1.8 0.6 1.7 1.7 1.3 1.0 0.9 0.3 1.5 -1.4 1.7 2.4 1.9 1.7 0.2 1.7 2.1 1.7 -0.1 1.4
Medication for cholesterol 4.5 6.8 15.8 2.8 2.7 3.2 2.1 2.9 2.5 1.3 2.5 2.4 2.7 2.7 1.2 3.3 2.9 4.0 3.2 -2.5 2.5 1.8 3.3 2.2 -0.5 2.9 2.6 2.0 2.6 2.7
Medication: Laxatives (e.g. Dulcolax, Senokot) 1.7 2.0 6.8 1.6 1.4 2.0 2.3 0.4 1.8 1.8 1.6 1.4 1.4 1.1 -0.3 1.6 1.7 1.1 1.1 -1.1 1.5 -0.6 0.8 0.5 -0.4 1.5 1.0 0.5 2.6 1.7
Back pain experienced in last month 0.2 0.3 2.2 -0.0 0.4 0.1 0.6 0.0 0.3 -0.1 0.3 0.5 0.5 0.2 -0.5 0.3 0.2 -1.0 0.3 -0.4 0.6 1.4 1.5 0.3 0.2 0.5 0.7 0.6 0.0 0.2
Mineral and other dietary supplements 0.5 0.6 5.5 -0.0 0.4 0.2 2.3 -2.0 1.8 1.2 0.5 0.3 0.1 0.2 -0.9 -0.2 0.3 0.2 0.1 0.2 0.2 0.5 0.3 -0.8 -0.8 -0.1 0.0 -0.4 0.1 0.0
Breast cancer (self-reported) 0.8 1.0 2.9 1.0 0.9 0.9 1.0 1.3 0.4 1.0 0.4 0.4 0.8 0.7 1.5 1.7 1.2 0.7 1.5 -0.6 1.0 0.5 0.5 0.6 -1.6 1.1 0.5 0.3 1.4 0.7
Asthma (self-reported) 0.1 0.1 1.5 -0.1 0.2 0.3 0.3 -1.2 0.6 -0.5 0.2 0.4 0.1 0.6 -0.4 -0.5 0.1 -0.3 -0.0 -0.0 -0.3 0.1 0.2 -0.2 0.3 0.1 0.2 0.1 -0.1 0.2
Osteoporosis (self-reported) 0.8 1.0 2.9 0.1 1.1 0.6 -0.5 1.2 -0.9 -1.5 1.1 0.7 0.9 -0.5 0.9 0.7 0.7 0.3 0.7 -1.2 0.9 0.7 1.3 1.7 1.2 1.3 0.8 1.4 1.3 1.1
Osteoarthritis (self-reported) 0.7 1.0 3.0 1.4 0.8 1.7 1.5 0.2 1.2 0.8 1.2 0.2 1.2 0.8 0.0 0.4 0.8 0.5 0.8 -0.6 1.0 1.3 0.2 0.1 -1.4 1.3 1.6 0.4 0.5 0.7
Medication: Aspirin 0.1 0.2 0.8 -0.4 0.1 -0.4 -0.7 0.3 -0.6 -0.6 -0.1 0.2 0.1 -0.2 0.8 0.1 -0.0 -0.7 -0.0 -0.2 -0.2 -0.9 0.0 0.6 0.0 0.0 -0.2 0.2 0.9 0.3
Medication: Gliclazide 1.0 1.2 5.0 -1.1 -0.9 -0.9 -0.9 -0.1 -2.1 -1.9 -1.2 -0.8 -1.0 -1.1 -0.4 -0.9 -0.8 -1.0 -0.9 0.6 -1.3 -2.2 -1.1 -0.3 0.4 -1.2 -1.2 -0.7 0.1 -0.5
Illnesses of father: None of the above (group 1) 0.3 0.3 1.6 0.3 0.6 0.5 1.3 -0.5 -0.2 -1.3 0.1 0.9 0.3 -0.5 -1.0 0.2 0.3 0.9 0.0 -0.5 0.2 -0.7 0.5 -0.0 -0.3 0.2 0.2 -0.0 0.6 0.3
Smoking status: Current 0.5 0.7 2.8 0.7 0.3 0.4 0.8 1.7 0.9 1.7 0.6 0.2 0.7 -0.1 0.5 1.3 0.3 0.1 0.9 -0.9 0.9 1.5 1.2 0.6 0.3 0.4 0.9 0.9 -0.3 0.7
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.2 0.4 1.6 0.4 0.3 0.5 0.6 -1.0 0.9 0.5 -0.1 0.7 -0.2 0.1 -1.1 0.2 0.5 0.4 -0.1 0.4 0.2 -1.1 -0.5 -1.2 -1.3 -0.6 -0.5 -0.8 0.5 0.0
Whole body water mass 0.1 0.7 4.3 -0.1 -0.4 0.1 1.9 -1.0 -0.0 0.3 -0.0 -0.8 -0.5 0.1 -1.0 -0.4 -0.1 -0.3 -0.5 1.1 -0.3 -0.4 -1.0 -1.4 -2.1 -0.6 -0.4 -1.5 -0.2 -0.4
Leg predicted mass (right) 0.1 0.6 4.3 -0.1 -0.5 -0.1 1.6 -0.7 -0.3 0.2 -0.2 -1.0 -0.5 -0.1 -0.5 -0.3 -0.2 -0.1 -0.4 1.1 -0.4 -0.3 -0.8 -1.3 -2.1 -0.5 -0.5 -1.4 -0.4 -0.6
Arm fat mass (left) 0.1 0.5 5.7 0.6 -0.0 0.4 2.4 0.5 -0.2 0.5 0.3 0.2 -0.0 0.1 -0.1 0.3 0.3 0.0 0.2 0.4 -0.1 -1.1 0.4 -0.8 -1.9 0.4 -0.3 -0.8 0.6 0.1
Number of self-reported non-cancer illnesses 2.6 4.6 8.1 -1.9 -2.1 -1.9 -1.5 -2.1 -2.2 -2.0 -2.2 -1.9 -2.4 -1.7 -2.4 -2.4 -2.5 -1.9 -2.1 2.4 -2.5 -2.8 -1.4 -2.2 -1.5 -2.4 -2.4 -2.5 -1.7 -2.2
Average weekly champagne plus white wine intake 0.4 0.5 1.5 -1.2 -0.7 -0.7 -0.9 -1.2 -0.3 0.7 -0.6 -0.6 -0.5 -1.1 -0.0 -1.2 -0.7 -1.0 -1.0 0.3 -0.8 0.4 -0.0 -0.3 0.6 -0.1 -0.3 0.1 -1.0 -0.7
Miserableness 0.6 1.1 4.2 -0.9 -1.3 -0.7 -0.1 -0.4 -0.3 -0.0 -1.1 -1.0 -0.9 -0.3 -1.8 -1.2 -1.5 0.1 -1.1 1.1 -1.0 0.2 0.7 -1.5 -1.3 -1.1 -0.8 -0.8 -2.0 -1.5
Guilty feelings 1.4 2.1 7.7 -1.1 -1.5 -1.1 -0.9 -2.8 0.7 0.5 -1.5 -0.5 -1.4 0.0 -1.9 -1.8 -1.5 -0.7 -1.8 1.7 -1.2 -0.8 -0.5 -2.2 -0.7 -1.6 -1.2 -1.4 -2.2 -1.7
Wears glasses or contact lenses 1.1 1.3 6.9 -0.8 -0.5 -0.5 -1.7 -1.1 -0.9 -1.8 -0.7 -1.7 -0.9 0.3 -0.0 -0.6 -0.5 -0.5 -0.4 1.0 -1.1 0.6 -2.6 -0.8 -1.9 -1.4 -0.9 -1.4 -0.7 -0.9
Ever taken oral contraceptive pill 0.1 0.2 1.5 0.2 -0.2 0.1 1.2 -0.8 0.6 0.4 0.1 0.7 0.2 0.4 -0.1 -0.3 0.1 -0.5 -0.2 -0.2 0.2 0.3 0.1 0.1 0.0 0.4 0.2 0.1 -0.2 0.0
Hearing aid user 0.3 0.4 1.4 -1.0 -0.6 -0.9 0.1 -1.2 0.3 0.3 -0.5 -0.5 -0.6 -0.3 -0.5 -1.0 -0.7 -1.1 -0.5 0.4 -0.7 -0.2 -0.4 -0.6 0.1 -0.8 -0.5 -0.2 -0.3 -0.5
Mother’s age at death 0.2 0.2 1.2 -0.3 0.1 0.1 0.7 -1.1 -0.5 -1.0 0.1 0.7 0.1 -0.6 -0.2 -0.6 0.4 -0.6 -0.5 0.1 -0.0 0.1 -0.8 -0.4 -0.7 0.2 0.0 -0.3 0.4 0.1
Financial situation satisfaction 1.1 1.4 8.4 1.2 0.8 1.5 2.7 -0.1 2.0 2.9 0.7 0.3 1.0 1.4 -0.3 0.7 1.0 0.4 0.9 -0.5 1.1 0.8 0.3 0.0 -1.4 0.9 1.1 0.5 -0.3 0.6
Tinnitus: Yes, now most or all of the time 0.2 0.3 1.7 -0.5 -0.5 -0.0 0.8 -0.4 0.2 -0.1 -0.3 -0.5 -0.5 0.4 -0.4 0.2 -0.4 -0.7 -0.3 0.7 -0.5 -0.0 -1.3 -0.9 -0.3 -0.4 -0.4 -0.6 -0.2 -0.5
Commuting to job workplace: Public transport 1.4 1.7 4.7 -1.4 -1.3 -1.5 -1.5 -0.3 -1.7 -2.0 -1.2 -1.6 -1.3 -0.6 -0.7 -1.0 -1.3 -2.2 -1.2 1.2 -1.3 0.3 -1.4 -0.8 0.4 -1.1 -1.0 -0.7 -1.9 -1.4
Eye problems/disorders: Glaucoma 1.1 1.3 4.0 -0.3 -0.9 -2.0 -1.0 0.2 -1.0 -0.2 -1.6 -1.9 -1.2 -0.3 0.7 -0.6 -0.8 -1.1 -0.6 1.2 -1.2 -0.0 -1.8 -1.1 -1.0 -1.4 -1.1 -1.0 -1.8 -1.5
Medication: Blood pressure 2.5 4.7 13.6 -2.1 -2.1 -2.6 -1.6 -1.1 -3.1 -1.5 -2.1 -2.7 -2.3 -2.6 0.1 -2.5 -2.3 -3.7 -2.4 2.1 -2.1 -1.1 -2.9 -1.7 0.3 -2.1 -2.3 -1.7 -1.9 -2.3
Pain type(s) experienced in last month: Hip pain 1.1 1.4 5.6 -1.5 -1.2 -1.2 -1.0 -0.7 -1.2 -1.5 -1.3 -1.3 -0.9 -1.2 -0.8 -0.6 -0.6 -2.4 -1.1 1.2 -1.1 -0.2 0.1 -1.5 -2.1 -0.7 -0.8 -1.2 -0.8 -1.3
Supplements: Fish oil (including cod liver oil) 1.5 1.9 4.3 1.2 1.3 1.0 -0.9 2.1 0.6 1.2 1.1 1.2 1.5 0.9 1.5 1.5 1.4 1.0 1.5 -1.7 1.3 1.1 1.6 1.9 1.2 1.1 1.5 1.7 1.5 1.8
High cholesterol (Self-reported) 0.1 0.2 1.3 0.5 0.3 0.2 -0.1 0.4 -0.0 -0.2 0.5 0.6 0.0 -0.0 0.3 0.1 -0.2 -0.4 0.2 -0.1 0.1 -1.1 0.3 0.6 0.2 -0.1 -0.2 0.2 1.0 0.4
Medication: Bendroflumethiazide 3.8 5.8 13.3 -2.2 -2.4 -3.1 -1.9 -0.3 -3.6 -1.7 -2.6 -3.6 -2.6 -3.3 0.3 -2.2 -2.3 -2.5 -2.6 2.4 -2.6 -1.4 -2.9 -2.0 0.1 -2.5 -2.6 -2.1 -2.3 -2.5
Medication: Paracetamol 0.6 0.9 1.9 1.2 1.1 0.8 0.9 0.5 0.6 -0.3 0.9 0.8 1.1 1.4 0.5 1.1 1.1 -0.5 1.4 -1.1 0.9 1.0 1.1 1.0 -0.4 0.8 1.1 1.0 1.2 1.1
Medication: Lisinopril 0.8 1.0 3.5 -1.4 -1.3 -1.3 -0.5 0.1 -1.3 -0.3 -0.9 -1.1 -1.1 -1.5 0.7 -0.5 -1.2 -1.9 -1.0 0.8 -1.0 -0.4 -0.1 -0.6 0.3 -1.2 -0.9 -0.4 -1.7 -1.0
Medication: Atorvastatin 1.6 1.9 3.5 -1.6 -1.4 -1.1 -1.2 -1.0 -1.5 -0.9 -1.4 -0.5 -1.7 -1.7 -1.9 -1.4 -1.8 -0.7 -1.5 1.5 -1.7 -1.4 -1.6 -1.4 -0.1 -1.6 -1.8 -1.4 -1.1 -1.5
Illnesses of father: High blood pressure 3.0 3.7 9.8 -1.3 -2.1 -2.2 -0.8 -0.8 -2.8 -2.6 -1.9 -2.6 -2.1 -0.9 -1.0 -2.3 -2.1 -1.7 -1.7 2.1 -2.1 -0.5 -2.4 -1.7 -0.3 -2.2 -1.6 -1.7 -3.1 -2.2
Alcohol drinker status: Never 1.1 1.4 2.8 1.5 1.5 1.0 0.4 1.4 0.6 -0.7 1.3 0.9 1.3 1.0 0.4 1.6 1.4 -0.3 1.7 -1.0 1.2 1.0 1.4 0.8 -1.6 1.0 1.3 0.6 1.5 1.3
Ever smoked 2.1 3.8 8.3 1.5 1.7 2.7 2.6 -0.3 2.8 2.6 1.9 2.9 2.1 1.7 1.1 1.5 1.9 0.9 1.9 -2.2 2.0 2.0 1.6 1.5 0.3 2.0 2.2 2.0 1.5 2.1
Basal metabolic rate 0.1 0.7 4.9 -0.0 -0.4 0.3 2.2 -0.8 0.0 0.4 0.0 -0.5 -0.4 0.2 -0.9 -0.2 -0.0 -0.2 -0.4 1.0 -0.3 -0.5 -0.7 -1.4 -2.1 -0.4 -0.4 -1.4 -0.0 -0.3
Leg fat percentage (left) 0.2 0.7 5.7 0.8 -0.1 0.6 2.4 1.4 -0.4 0.9 0.1 0.0 0.1 0.3 0.1 0.6 0.5 -0.1 0.4 0.2 -0.0 -1.1 0.2 -0.7 -2.2 0.4 -0.2 -0.7 0.5 0.1
Arm fat-free mass (left) 0.2 1.1 6.7 -0.0 -0.7 -0.1 2.2 -1.0 -0.2 0.0 -0.2 -1.0 -0.7 0.2 -1.2 -0.6 -0.3 -0.7 -0.7 1.4 -0.6 -0.6 -1.1 -1.8 -2.6 -0.8 -0.6 -1.9 -0.5 -0.7
Number of operations (self-reported) 0.7 1.0 4.6 -0.9 -0.9 -0.8 2.1 -0.9 0.2 2.0 -0.8 -0.4 -0.9 -1.1 -1.1 -0.9 -1.1 -1.0 -0.9 0.8 -0.5 0.2 0.3 -1.2 -0.9 -0.8 -0.7 -0.7 -1.6 -1.3
Average weekly beer plus cider intake 0.7 1.0 9.8 1.4 0.1 1.0 3.1 0.7 1.0 2.6 0.6 0.2 0.2 0.6 -0.3 0.5 0.4 1.0 0.6 0.0 0.6 -0.6 0.1 -0.6 -1.4 -0.2 0.0 -0.5 0.6 0.5
Irritability 0.1 0.1 1.0 0.1 -0.3 0.5 0.7 -0.1 0.4 0.2 0.2 -0.2 0.2 0.6 0.1 0.1 -0.0 -0.0 -0.2 0.0 0.1 1.0 -0.1 -0.2 -0.1 -0.3 0.2 0.1 -0.2 0.0
Risk taking 0.3 0.5 2.9 0.6 0.5 0.7 -1.0 0.6 1.0 0.8 0.4 -0.2 0.5 1.1 0.2 0.6 0.6 0.7 0.8 -0.2 0.5 0.9 -0.5 0.0 -1.7 0.7 0.5 -0.3 0.1 0.2
Ever had prostate specific antigen (PSA) test 0.5 0.6 5.1 -0.6 -0.5 -1.2 -2.3 -0.1 -0.7 -1.0 -0.4 -1.0 -0.5 -0.5 -0.2 -1.1 -0.6 0.0 -0.7 0.3 -0.5 -0.8 -0.1 0.1 0.7 -0.6 -0.2 -0.2 -0.7 -0.2
Fractured/broken bones in last 5 years 1.3 1.6 3.4 -1.7 -1.6 -1.4 -0.1 -1.3 -1.3 -0.5 -1.2 -0.8 -1.5 -1.0 -1.4 -1.8 -1.1 -0.4 -1.4 1.5 -1.4 -1.8 -1.0 -1.5 -0.7 -1.5 -1.4 -1.4 -0.4 -1.2
Age started oral contraceptive pill 0.5 0.6 4.9 -0.0 -0.2 -0.7 -1.1 0.5 -0.9 -1.1 -0.3 -1.6 -0.2 -0.4 -0.3 -0.9 -0.2 -0.6 -0.3 0.6 -0.5 0.6 -0.9 -0.9 -2.2 0.1 -0.2 -0.7 -0.5 -0.8
Diastolic blood pressure, automated reading 0.3 0.8 3.7 0.3 -0.7 -0.4 0.6 0.4 -1.9 -1.2 -0.3 -1.5 -0.5 -0.9 -0.4 -0.7 -0.4 -1.1 -0.9 0.9 -0.9 -1.4 -0.9 -0.9 -1.1 -0.6 -0.6 -1.2 -0.1 -0.4
Ever depressed for a whole week 0.6 0.8 3.3 1.1 0.7 1.1 0.0 -0.9 1.8 1.7 0.9 1.6 0.8 0.6 0.4 0.2 0.5 0.4 0.4 -0.8 1.0 -0.3 0.4 0.6 0.5 0.8 0.9 0.8 0.5 0.9
Unable to work because of sickness or disability 1.7 2.2 12.6 1.5 1.1 1.7 3.5 0.3 2.0 2.5 1.3 0.9 0.9 1.6 -0.3 0.9 1.1 2.5 0.9 -0.3 0.8 0.1 2.0 -0.0 -2.1 1.0 0.7 -0.4 1.5 0.9
Commuting to job workplace: Cycle 2.4 2.9 12.5 -1.7 -1.8 -1.9 -3.5 -1.0 -1.7 -1.2 -2.2 -1.4 -2.0 -1.5 -0.8 -1.9 -1.5 -0.8 -1.9 1.7 -1.8 -1.3 -1.6 -1.2 0.3 -1.7 -2.0 -1.7 -1.6 -2.0
Myopia 1.9 2.8 6.9 -1.0 -1.6 -1.4 -0.6 -1.2 -1.7 -1.1 -1.7 -1.9 -2.0 -1.2 -1.8 -1.2 -1.6 0.5 -1.4 2.2 -1.6 -1.8 -2.2 -2.2 -1.5 -2.4 -2.1 -2.6 -1.0 -1.7
Vascular/heart problems diagnosed by doctor 2.0 5.4 11.9 2.5 2.6 2.9 1.6 0.9 3.5 1.5 2.4 2.7 2.6 2.5 0.2 2.6 2.7 3.1 2.7 -2.2 2.7 2.0 2.0 1.6 -0.1 2.5 2.5 1.8 2.1 2.5
Cholesterol lowering medication 1.7 2.5 6.9 -1.2 -1.4 -1.4 -1.2 -1.1 -1.5 -1.8 -1.3 -1.1 -1.7 -1.5 -1.2 -1.2 -1.8 -2.3 -1.5 1.7 -1.6 -1.9 -2.6 -1.6 -1.1 -1.6 -1.9 -1.7 -0.9 -1.6
Medication: Omeprazole (e.g. Zanprol) 1.5 1.8 5.1 -1.0 -1.4 -1.2 -0.3 -1.1 -0.7 0.1 -1.4 -0.8 -1.6 -0.1 -1.2 -1.1 -1.2 -1.2 -1.1 1.8 -1.5 -1.2 -1.5 -1.9 -2.3 -1.6 -1.7 -1.9 -1.5 -1.6
Pain experienced in last month 0.2 0.3 2.9 -0.1 0.4 0.2 -0.3 -1.7 0.3 0.4 -0.1 0.4 -0.1 -0.4 0.8 -0.5 0.4 1.1 -0.3 -0.1 -0.2 -0.6 -1.3 0.0 0.4 -0.1 -0.4 0.0 0.9 0.2
Supplements: Calcium 1.4 1.6 6.9 -0.8 -1.3 -1.6 -1.1 0.4 -2.6 -1.9 -1.3 -1.6 -1.3 -1.3 -0.2 -1.1 -1.3 -1.1 -1.0 1.1 -1.4 -1.1 -1.4 -0.7 -0.3 -0.9 -1.3 -1.0 -0.8 -1.4
Basal cell carcinoma (self-reported) 0.8 0.9 2.5 1.3 1.4 1.1 0.6 1.3 -0.0 -0.8 0.6 1.1 0.9 0.8 0.9 1.6 1.0 1.1 1.6 -1.0 0.9 0.5 -0.2 0.9 0.1 0.9 0.9 0.8 0.6 0.9
Heart attack/myocardial infarction (self-reported) 0.3 0.4 4.1 0.2 -0.1 -0.9 0.2 -0.1 0.3 2.0 -0.2 -0.1 0.1 -0.6 1.3 -0.3 -0.0 -1.2 -0.2 -0.4 -0.1 1.1 -0.5 0.4 0.3 0.2 0.2 0.7 -0.2 -0.2
Deep venous thrombosis (DVT) (self-reported) 0.6 0.8 1.8 -0.3 -0.7 -0.9 -0.2 -0.3 -1.0 -1.1 -1.3 -1.0 -1.1 -0.4 -0.9 -1.2 -0.9 0.9 -0.8 1.0 -1.1 -1.2 0.1 -0.8 0.1 -1.2 -1.1 -1.2 -0.9 -1.0
Heart disease (siblings) 0.4 0.5 4.7 0.7 -0.0 -0.3 1.8 0.1 -0.0 2.2 -0.1 -1.2 -0.0 -0.9 0.4 -0.5 -0.3 0.0 0.1 0.3 -0.3 1.3 -0.3 -0.6 -0.7 0.1 0.1 -0.2 -0.6 -0.4
Alcohol drinker status: Previous 1.5 1.7 7.1 -1.9 -1.6 -0.7 -1.9 -1.0 -1.0 -0.1 -1.3 -1.0 -1.2 -1.2 -0.7 -1.5 -1.3 -2.7 -1.6 1.0 -1.1 -0.6 -1.4 -1.2 0.0 -0.8 -1.2 -0.8 -1.6 -1.3
Pack years of smoking 0.7 1.1 4.6 1.7 0.9 0.9 1.1 1.8 0.4 0.9 0.7 -0.2 0.9 0.5 0.5 1.0 0.9 1.9 1.1 -0.5 0.9 1.3 0.2 0.1 -2.1 1.1 0.9 0.2 0.1 0.4
Impedance of whole body 0.5 2.8 12.3 0.6 1.5 0.9 -1.9 2.3 0.4 0.3 0.9 0.9 1.5 0.8 2.3 1.7 1.2 1.1 1.6 -2.3 1.3 0.6 0.9 3.0 3.5 1.4 1.3 2.7 1.4 1.7
Leg fat mass (left) 0.2 0.8 7.6 0.7 -0.1 0.6 2.8 0.9 -0.4 0.8 0.1 -0.2 -0.0 0.4 -0.1 0.4 0.4 -0.3 0.2 0.5 -0.1 -1.1 -0.1 -1.1 -2.7 0.3 -0.3 -1.1 0.5 -0.0
Arm predicted mass (left) 0.2 0.9 6.2 0.2 -0.5 0.2 2.5 -0.9 -0.1 0.1 -0.0 -0.7 -0.4 0.3 -1.1 -0.4 0.0 -0.5 -0.5 1.2 -0.3 -0.5 -1.1 -1.6 -2.5 -0.6 -0.5 -1.7 -0.2 -0.4