Best TWAS P=2.3e-13 · Best GWAS P=6.59e-14 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Gastroesophageal Junction | SEC61A2 | 0.28 | 0.13 | enet | 15 | 0.10 | 1.7e-04 | 5.0 | -5.2 | 2.6e-07 | -0.43 | 0.36 | 0.14 | FALSE |
| 2 | GTEx | Lung | CAMK1D | 0.28 | 0.24 | enet | 25 | 0.24 | 2.3e-18 | 7.5 | 7.3 | 2.3e-13 | 0.96 | 0.00 | 1.00 | TRUE |
| 3 | NTR | Blood | CAMK1D | 0.10 | 0.09 | bslmm | 900 | 0.08 | 4.4e-25 | 7.5 | 7.0 | 2.5e-12 | 0.97 | 0.00 | 1.00 | FALSE |
| 4 | YFS | Blood | CAMK1D | 0.27 | 0.23 | bslmm | 875 | 0.26 | 7.7e-86 | 7.5 | 6.3 | 2.1e-10 | 0.93 | 0.00 | 1.00 | FALSE |
| 5 | YFS | Blood | NUDT5 | 0.13 | 0.12 | enet | 40 | 0.13 | 1.1e-41 | 7.5 | 5.7 | 1.4e-08 | 0.90 | 0.00 | 1.00 | FALSE |
| 6 | The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | CDC123 | 0.26 | 0.07 | lasso | 4 | 0.07 | 1.4e-03 | 6.5 | -5.6 | 2.0e-08 | -0.85 | 0.01 | 0.92 | FALSE |