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chr16:52,772,129-54,235,440

Best TWAS P=3e-09 · Best GWAS P=3.06e-29 conditioned to 3.52e-29

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	AKTIP	0.12	0.09	enet	10	0.08	1.9e-10	-5.4	5.4	7.1e-08	0.07	1.00	0.00	FALSE
2	CommonMind	Brain Pre-frontal Cortex	RBL2	0.22	0.24	enet	15	0.26	1.8e-31	-5.4	5.4	5.1e-08	0.02	1.00	0.00	FALSE
3	GTEx	Adipose Subcutaneous	RBL2	0.34	0.28	enet	18	0.30	1.0e-24	-5.4	5.3	1.2e-07	0.02	1.00	0.00	FALSE
4	GTEx	Adipose Visceral Omentum	RBL2	0.30	0.27	lasso	2	0.27	4.3e-14	-5.4	5.4	5.9e-08	0.04	1.00	0.00	FALSE
5	GTEx	Adrenal Gland	RBL2	0.35	0.27	enet	22	0.25	2.3e-09	-5.4	5.7	1.2e-08	0.04	1.00	0.00	FALSE
6	GTEx	Artery Aorta	RBL2	0.27	0.21	enet	14	0.19	1.5e-10	-5.4	5.6	2.3e-08	0.04	1.00	0.00	FALSE
7	GTEx	Artery Coronary	RBL2	0.36	0.33	enet	14	0.27	1.4e-09	-5.4	5.3	1.1e-07	0.05	1.00	0.00	FALSE
8	GTEx	Artery Tibial	RBL2	0.16	0.17	enet	11	0.20	2.1e-15	-5.4	5.3	9.9e-08	0.02	1.00	0.00	FALSE
9	GTEx	Brain Cerebellar Hemisphere	RBL2	0.55	0.55	enet	20	0.46	2.1e-13	-5.4	5.5	3.4e-08	0.04	1.00	0.00	FALSE
10	GTEx	Brain Cerebellum	RBL2	0.66	0.72	enet	16	0.70	5.7e-28	-5.4	5.5	4.8e-08	0.05	1.00	0.00	FALSE
11	GTEx	Breast Mammary Tissue	RBL2	0.36	0.35	lasso	3	0.36	3.0e-19	-5.5	5.5	3.6e-08	0.04	1.00	0.00	FALSE
12	GTEx	Breast Mammary Tissue (Male)	RBL2	0.40	0.29	lasso	2	0.25	1.4e-06	-5.5	5.5	3.8e-08	0.04	0.60	0.02	FALSE
13	GTEx	Breast Mammary Tissue (Female)	RBL2	0.47	0.27	lasso	7	0.20	1.1e-06	-5.3	5.6	1.9e-08	0.04	0.97	0.00	FALSE
14	GTEx	Cells EBV-transformed lymphocytes	RBL2	0.33	0.12	lasso	6	0.08	1.1e-03	-5.3	5.4	5.5e-08	0.06	0.27	0.05	FALSE
15	GTEx	Cells Transformed fibroblasts	RBL2	0.13	0.05	enet	9	0.02	8.9e-03	-5.5	5.7	9.2e-09	0.06	0.55	0.02	FALSE
16	GTEx	Colon Sigmoid	RBL2	0.38	0.37	lasso	12	0.29	8.4e-11	-5.4	5.5	4.7e-08	0.03	1.00	0.00	FALSE
17	GTEx	Colon Transverse	RBL2	0.59	0.44	enet	13	0.52	4.4e-28	-5.4	5.7	1.5e-08	0.05	1.00	0.00	FALSE
18	GTEx	Esophagus Gastroesophageal Junction	RBL2	0.38	0.40	enet	17	0.38	1.1e-14	-5.4	5.5	3.2e-08	0.05	1.00	0.00	FALSE
19	GTEx	Esophagus Mucosa	RBL2	0.36	0.36	enet	37	0.37	2.9e-26	-5.4	5.9	3.0e-09	0.00	1.00	0.00	TRUE
20	GTEx	Esophagus Muscularis	RBL2	0.36	0.38	enet	10	0.41	6.8e-27	-5.4	5.4	5.4e-08	0.05	1.00	0.00	FALSE
21	GTEx	Heart Atrial Appendage	RBL2	0.28	0.14	enet	25	0.23	8.6e-11	-5.4	5.8	6.9e-09	0.03	1.00	0.00	FALSE
22	GTEx	Lung	RBL2	0.29	0.37	enet	16	0.35	9.1e-28	-5.4	5.4	7.4e-08	0.03	1.00	0.00	FALSE
23	GTEx	Nerve Tibial	RBL2	0.46	0.52	enet	19	0.53	1.6e-43	-5.4	5.5	3.4e-08	0.04	1.00	0.00	FALSE
24	GTEx	Ovary	RBL2	0.41	0.26	enet	29	0.18	3.2e-05	-5.4	5.2	2.0e-07	0.16	0.70	0.04	FALSE
25	GTEx	Pancreas	RBL2	0.36	0.36	enet	26	0.36	5.9e-16	-5.4	5.8	5.0e-09	0.08	1.00	0.00	FALSE
26	GTEx	Pituitary	RBL2	0.36	0.39	lasso	6	0.40	4.5e-11	-5.4	-5.4	6.4e-08	-0.04	0.98	0.00	FALSE
27	GTEx	Prostate	RBL2	0.55	0.45	lasso	4	0.45	1.0e-12	-5.5	5.4	5.6e-08	0.04	0.99	0.00	FALSE
28	GTEx	Skin Not Sun Exposed Suprapubic	RBL2	0.35	0.33	enet	16	0.34	2.6e-19	-5.5	5.4	5.7e-08	0.03	1.00	0.00	FALSE
29	GTEx	Skin Sun Exposed Lower leg	RBL2	0.35	0.39	enet	25	0.37	2.9e-32	-5.5	5.4	6.2e-08	0.03	1.00	0.00	FALSE
30	GTEx	Thyroid	RBL2	0.34	0.47	lasso	4	0.45	3.6e-38	-5.4	5.4	5.8e-08	0.04	1.00	0.00	FALSE
31	GTEx	Vagina	RBL2	0.41	0.37	enet	13	0.34	1.6e-08	-5.3	5.3	8.9e-08	0.03	0.89	0.01	FALSE
32	NTR	Blood	RBL2	0.09	0.11	bslmm	419	0.11	1.1e-33	-5.4	5.8	6.3e-09	0.06	1.00	0.00	FALSE
33	YFS	Blood	RBL2	0.18	0.26	bslmm	381	0.27	6.9e-90	-5.4	5.6	2.5e-08	0.09	1.00	0.00	FALSE
34	The Cancer Genome Atlas	Esophageal Carcinoma	RBL2	0.08	0.04	lasso	3	0.03	4.4e-02	-4.2	-5.3	1.3e-07	0.00	0.02	0.57	FALSE
35	The Cancer Genome Atlas	Brain Lower Grade Glioma	AKTIP	0.04	0.03	blup	42	0.05	1.9e-06	-5.5	5.3	1.0e-07	0.04	0.01	0.99	FALSE
36	The Cancer Genome Atlas	Brain Lower Grade Glioma	RBL2	0.03	0.06	enet	5	0.05	8.2e-07	-5.3	5.6	1.8e-08	0.04	0.02	0.98	FALSE