Best TWAS P=3.95e-09 · Best GWAS P=8.06e-09 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | CHMP4B | 0.27 | 0.23 | enet | 14 | 0.22 | 6.9e-27 | -5.8 | -5.7 | 1.5e-08 | 0.99 | 0.01 | 0.99 | FALSE |
| 2 | METSIM | Adipose | CHMP4B | 0.05 | 0.02 | lasso | 6 | 0.02 | 1.0e-03 | -5.8 | -5.9 | 3.9e-09 | 0.99 | 0.01 | 0.99 | TRUE |
| 3 | NTR | Blood | CHMP4B | 0.06 | 0.04 | bslmm | 253 | 0.04 | 1.6e-12 | -5.7 | -5.4 | 6.1e-08 | 0.90 | 0.01 | 0.99 | FALSE |