Best TWAS P=9.55e-10 · Best GWAS P=5.73e-13 conditioned to 0.000493
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | EML2 | 0.06 | 0.03 | lasso | 6 | 0.03 | 4.3e-05 | 3.5 | -5.3 | 8.8e-08 | 0.38 | 0.17 | 0.78 | FALSE |
| 2 | GTEx | Whole Blood | PPM1N | 0.06 | 0.00 | enet | 24 | 0.03 | 5.2e-04 | 3.0 | 6.1 | 9.5e-10 | -0.18 | 0.14 | 0.03 | TRUE |
| 3 | The Cancer Genome Atlas | Skin Cutaneous Melanoma | SNRPD2 | 0.15 | 0.01 | lasso | 2 | 0.08 | 3.4e-03 | -4.8 | -5.7 | 1.0e-08 | 0.58 | 0.01 | 0.54 | TRUE |