Best TWAS P=2.01e-15 · Best GWAS P=5e-13 conditioned to 0.874
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Breast Mammary Tissue (Male) | RP11-412D9.4 | 0.26 | 0.03 | lasso | 5 | 0.02 | 1.1e-01 | -6.9 | -6.7 | 2.3e-11 | -0.73 | 0.06 | 0.28 | FALSE |
| 2 | The Cancer Genome Atlas | Colon Adenocarcinoma | RIC8B | 0.06 | 0.02 | blup | 73 | 0.02 | 2.0e-02 | 6.9 | -7.9 | 2.0e-15 | -0.92 | 0.02 | 0.75 | TRUE |
| 3 | The Cancer Genome Atlas | Prostate Adenocarcinoma | RFX4 | 0.05 | 0.07 | lasso | 4 | 0.07 | 4.9e-08 | 3.9 | 5.9 | 3.6e-09 | 0.73 | 0.16 | 0.84 | FALSE |