Best TWAS P=3.01e-12 · Best GWAS P=2.1e-40 conditioned to 4.34e-24
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Cerebellum | CDADC1 | 0.24 | 0.27 | lasso | 8 | 0.25 | 5.7e-08 | 5.0 | -5.1 | 3.1e-07 | 0.05 | 0.04 | 0.95 | TRUE |
| 2 | GTEx | Breast Mammary Tissue (Male) | RNASEH2B | 0.06 | -0.01 | enet | 25 | -0.01 | 5.4e-01 | -1.7 | -7.0 | 3.0e-12 | 0.52 | 0.04 | 0.30 | TRUE |
| 3 | GTEx | Esophagus Mucosa | EBPL | 0.44 | 0.16 | enet | 35 | 0.24 | 2.6e-16 | 3.6 | 5.4 | 8.6e-08 | -0.05 | 0.56 | 0.43 | TRUE |
| 4 | The Cancer Genome Atlas | Pancreatic Adenocarcinoma | EBPL | 0.21 | 0.09 | enet | 10 | 0.13 | 4.9e-06 | -5.5 | 5.2 | 2.2e-07 | -0.26 | 0.00 | 0.99 | TRUE |