Best TWAS P=3.53e-09 · Best GWAS P=2.8e-09 conditioned to 0.000298
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | CARM1 | 0.06 | 0.01 | bslmm | 392 | 0.03 | 3.6e-04 | -2.7 | 5.9 | 3.5e-09 | -0.46 | 0.2 | 0.2 | TRUE |
2 | GTEx | Skin Sun Exposed Lower leg | SMARCA4 | 0.15 | 0.10 | enet | 25 | 0.15 | 1.4e-12 | -1.5 | 5.3 | 1.2e-07 | -0.70 | 0.4 | 0.6 | FALSE |