[Hub]/) : Traits : Waist Hip Ratio (WHR) : ← →

chr2:206,159,496-207,874,372

Best TWAS P=8.89e-13 · Best GWAS P=7.07e-13 conditioned to 0.0123

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	NDUFS1	0.10	0.09	lasso	9	0.09	1.2e-10	6.7	-6.6	3.4e-11	-0.93	0.02	0.98	FALSE
2	GTEx	Adipose Subcutaneous	NDUFS1	0.08	0.05	lasso	5	0.01	2.0e-02	6.6	-6.6	3.2e-11	-0.95	0.03	0.96	FALSE
3	GTEx	Adipose Subcutaneous	AC007383.4	0.08	0.05	lasso	4	0.04	2.8e-04	6.3	-6.2	5.2e-10	-0.89	0.02	0.97	FALSE
4	GTEx	Adipose Visceral Omentum	AC007383.4	0.10	0.01	lasso	4	0.02	4.8e-02	5.4	-6.2	6.0e-10	-0.77	0.03	0.74	FALSE
5	GTEx	Artery Aorta	NDUFS1	0.11	0.07	enet	29	0.01	6.7e-02	6.8	-6.0	2.0e-09	-0.83	0.02	0.96	FALSE
6	GTEx	Artery Tibial	NDUFS1	0.16	0.15	enet	14	0.15	3.9e-12	6.8	-6.9	4.9e-12	-0.98	0.02	0.98	FALSE
7	GTEx	Brain Cerebellum	NDUFS1	0.13	0.15	lasso	2	0.10	5.3e-04	6.3	-6.3	2.8e-10	-0.90	0.04	0.87	FALSE
8	GTEx	Brain Cerebellum	AC007383.4	0.23	0.05	lasso	3	0.18	3.9e-06	5.5	-5.7	1.1e-08	-0.77	0.04	0.85	FALSE
9	GTEx	Brain Frontal Cortex BA9	NDUFS1	0.36	0.33	lasso	3	0.32	3.9e-09	6.3	-6.2	4.3e-10	-0.90	0.03	0.97	FALSE
10	GTEx	Brain Frontal Cortex BA9	AC007383.4	0.39	0.36	lasso	3	0.35	3.3e-10	6.4	-6.5	8.6e-11	-0.94	0.03	0.97	FALSE
11	GTEx	Brain Putamen basal ganglia	NDUFS1	0.16	0.06	enet	6	0.05	2.9e-02	6.2	-6.4	2.0e-10	-0.84	0.03	0.76	FALSE
12	GTEx	Cells Transformed fibroblasts	NDUFS1	0.33	0.42	enet	28	0.40	3.2e-32	6.8	-6.7	2.4e-11	-0.96	0.03	0.97	FALSE
13	GTEx	Cells Transformed fibroblasts	AC007383.4	0.18	0.15	enet	28	0.17	4.5e-13	6.8	-6.9	5.8e-12	-0.91	0.03	0.97	FALSE
14	GTEx	Colon Sigmoid	AC007383.4	0.15	0.14	enet	13	0.09	3.8e-04	6.8	-7.1	1.7e-12	-0.92	0.03	0.96	FALSE
15	GTEx	Colon Transverse	AC007383.4	0.14	0.09	lasso	2	0.06	8.8e-04	6.6	-6.5	7.0e-11	-0.90	0.02	0.92	FALSE
16	GTEx	Esophagus Gastroesophageal Junction	NDUFS1	0.16	0.09	enet	22	0.03	2.4e-02	6.8	-6.9	5.8e-12	-0.85	0.03	0.94	FALSE
17	GTEx	Esophagus Gastroesophageal Junction	AC007383.4	0.21	0.17	enet	11	0.14	8.5e-06	6.8	-6.8	8.4e-12	-0.96	0.02	0.97	FALSE
18	GTEx	Esophagus Mucosa	NDUFS1	0.09	0.05	lasso	2	0.02	8.6e-03	7.2	-7.1	1.4e-12	-0.97	0.01	0.98	FALSE
19	GTEx	Esophagus Mucosa	AC007383.4	0.16	0.08	enet	26	0.10	5.8e-07	6.8	-7.1	1.1e-12	-0.79	0.02	0.98	FALSE
20	GTEx	Esophagus Muscularis	NDUFS1	0.17	0.19	enet	21	0.18	5.1e-11	6.8	-7.0	2.4e-12	-0.93	0.03	0.97	FALSE
21	GTEx	Esophagus Muscularis	AC007383.4	0.10	0.13	enet	4	0.10	1.3e-06	6.8	-6.8	1.1e-11	-0.96	0.02	0.98	FALSE
22	GTEx	Heart Atrial Appendage	AC007383.4	0.12	0.10	enet	21	0.09	9.8e-05	6.8	-6.7	2.9e-11	-0.90	0.03	0.97	FALSE
23	GTEx	Heart Left Ventricle	AC007383.4	0.17	0.13	enet	19	0.16	9.7e-09	6.7	-6.3	3.4e-10	-0.90	0.03	0.97	FALSE
24	GTEx	Liver	AC007383.4	0.27	0.10	lasso	4	0.03	4.4e-02	6.2	-6.0	1.5e-09	-0.88	0.04	0.66	FALSE
25	GTEx	Muscle Skeletal	NDUFS1	0.20	0.14	enet	20	0.12	4.0e-12	6.7	-6.7	2.4e-11	-0.95	0.04	0.96	FALSE
26	GTEx	Muscle Skeletal	AC007383.4	0.23	0.18	enet	38	0.20	2.1e-19	6.7	-5.8	5.9e-09	-0.86	0.04	0.96	FALSE
27	GTEx	Nerve Tibial	NDUFS1	0.13	0.08	enet	14	0.05	3.1e-04	6.3	-6.7	1.8e-11	-0.91	0.04	0.96	FALSE
28	GTEx	Nerve Tibial	AC007383.4	0.14	0.06	lasso	6	0.05	3.0e-04	6.8	-6.7	2.9e-11	-0.94	0.03	0.97	FALSE
29	GTEx	Pituitary	AC007383.4	0.31	0.05	enet	15	0.04	3.9e-02	6.1	-6.7	2.2e-11	-0.88	0.04	0.75	FALSE
30	GTEx	Skin Sun Exposed Lower leg	AC007383.4	0.12	0.07	enet	21	0.07	3.9e-06	6.7	-5.2	1.9e-07	-0.79	0.03	0.97	FALSE
31	GTEx	Testis	NDUFS1	0.15	0.08	lasso	6	0.08	2.1e-04	4.8	-6.3	3.6e-10	-0.65	0.08	0.83	FALSE
32	GTEx	Thyroid	NDUFS1	0.21	0.10	enet	39	0.05	7.4e-05	6.8	-7.2	8.9e-13	-0.79	0.02	0.98	TRUE
33	GTEx	Whole Blood	AC007383.4	0.07	0.03	enet	11	0.03	6.0e-04	5.4	-5.8	7.1e-09	-0.67	0.09	0.85	FALSE
34	METSIM	Adipose	NDUFS1	0.12	0.18	lasso	4	0.17	5.2e-25	6.8	-6.8	7.5e-12	-0.97	0.02	0.98	FALSE
35	METSIM	Adipose	ZDBF2	0.03	0.00	bslmm	436	0.00	1.1e-01	-5.4	6.1	1.1e-09	0.65	0.27	0.53	FALSE
36	ROSMAP	Brain Pre-frontal Cortex	INO80D	0.22	0.34	lasso	2	0.35	2.0e-47	4.9	5.9	3.3e-09	0.83	1.00	0.00	FALSE
37	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	NDUFS1	0.05	0.05	enet	6	0.06	2.3e-07	7.2	-6.6	4.5e-11	-0.92	0.01	0.99	FALSE
38	The Cancer Genome Atlas	Brain Lower Grade Glioma	NDUFS1	0.05	0.03	blup	51	0.04	6.2e-05	6.8	-6.8	1.1e-11	-0.87	0.03	0.96	FALSE
39	The Cancer Genome Atlas	Thyroid Carcinoma	NDUFS1	0.07	0.04	enet	5	0.06	3.9e-06	-3.2	-5.5	4.6e-08	-0.62	0.10	0.45	FALSE