Best TWAS P=3.3e-09 · Best GWAS P=1.58e-11 conditioned to 4.42e-08
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Cerebellum | ITGA9 | 0.39 | 0.18 | lasso | 5 | 0.21 | 8.8e-07 | -6.6 | 5.9 | 3.3e-09 | 0.16 | 0.02 | 0.95 | TRUE |
| 2 | METSIM | Adipose | ITGA9 | 0.08 | 0.05 | bslmm | 532 | 0.06 | 9.3e-10 | -6.5 | -5.3 | 9.8e-08 | -0.46 | 0.02 | 0.98 | FALSE |
| 3 | The Cancer Genome Atlas | Brain Lower Grade Glioma | ITGA9 | 0.05 | 0.01 | blup | 229 | 0.02 | 2.2e-03 | 2.7 | -5.4 | 6.9e-08 | -0.34 | 0.05 | 0.42 | FALSE |
| 4 | The Cancer Genome Atlas | Thyroid Carcinoma | ITGA9 | 0.05 | 0.05 | lasso | 4 | 0.06 | 1.6e-06 | -4.4 | 5.8 | 5.1e-09 | 0.16 | 0.52 | 0.37 | TRUE |