Best TWAS P=3.65e-09 · Best GWAS P=1.56e-09 conditioned to 1.38e-10
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | WDR5 | 0.13 | 0.08 | lasso | 1 | 0.05 | 5.8e-05 | -5.7 | -5.7 | 1.3e-08 | -0.08 | 0.00 | 1.00 | FALSE |
| 2 | GTEx | Artery Tibial | WDR5 | 0.26 | 0.12 | lasso | 7 | 0.13 | 3.2e-10 | -5.7 | -5.6 | 2.5e-08 | -0.08 | 0.00 | 1.00 | FALSE |
| 3 | GTEx | Cells Transformed fibroblasts | WDR5 | 0.26 | 0.16 | lasso | 3 | 0.16 | 4.6e-12 | -5.6 | -5.8 | 8.7e-09 | -0.07 | 0.00 | 1.00 | FALSE |
| 4 | GTEx | Testis | WDR5 | 0.45 | 0.29 | lasso | 9 | 0.26 | 1.0e-11 | -5.6 | -5.9 | 3.7e-09 | -0.06 | 0.01 | 0.99 | TRUE |