Best TWAS P=3.17e-08 · Best GWAS P=2.29e-09 conditioned to 0.0185
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NTR | Blood | PARK7 | 0.02 | 0.01 | lasso | 3 | 0.01 | 1.4e-05 | -5.4 | -5.5 | 3.2e-08 | 0.87 | 0.03 | 0.97 | TRUE |
| 2 | YFS | Blood | PARK7 | 0.08 | 0.11 | lasso | 6 | 0.11 | 4.4e-34 | -5.4 | -5.4 | 7.9e-08 | 0.84 | 0.06 | 0.94 | FALSE |
| 3 | The Cancer Genome Atlas | Breast Invasive Carcinoma | ERRFI1 | 0.01 | 0.01 | blup | 27 | 0.00 | 4.3e-02 | -5.4 | 5.5 | 3.6e-08 | -0.88 | 0.01 | 0.84 | FALSE |
| 4 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | PARK7 | 0.03 | 0.03 | enet | 3 | 0.02 | 1.3e-03 | -5.3 | -5.2 | 2.4e-07 | 0.88 | 0.01 | 0.93 | FALSE |
| 5 | The Cancer Genome Atlas | Lung Adenocarcinoma | PARK7 | 0.03 | 0.03 | lasso | 1 | 0.02 | 5.0e-03 | -5.4 | -5.4 | 5.6e-08 | 0.84 | 0.00 | 0.86 | FALSE |
| 6 | The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | PARK7 | 0.22 | 0.00 | blup | 35 | 0.03 | 2.2e-02 | -5.5 | -5.3 | 1.0e-07 | 0.63 | 0.00 | 0.51 | FALSE |