[Hub]/) : Traits : Ulcerative Colitis :

chr1:1,781,220-3,219,950

Best TWAS P=7.89e-10 · Best GWAS P=7.95e-10 conditioned to 0.0218

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Brain Cerebellum TNFRSF14 0.17 0.07 enet 6 0.10 7.6e-04 -5.7 -5.8 6.3e-09 0.91 0.01 0.95 FALSE
2 GTEx Brain Cerebellum RP3-395M20.8 0.19 0.05 enet 8 0.06 5.9e-03 -4.0 -5.6 2.0e-08 0.83 0.02 0.90 FALSE
3 GTEx Esophagus Muscularis RP3-395M20.12 0.08 0.06 enet 6 0.06 2.3e-04 -5.7 6.1 1.1e-09 -0.85 0.01 0.98 FALSE
4 GTEx Pancreas TNFRSF14 0.13 0.04 enet 8 0.04 1.0e-02 -5.7 -5.7 1.5e-08 0.89 0.02 0.96 FALSE
5 GTEx Spleen RP3-395M20.9 0.42 0.14 lasso 3 0.15 1.1e-04 5.0 5.2 1.8e-07 -0.66 0.05 0.67 FALSE
6 GTEx Uterus RP3-395M20.9 0.25 0.08 lasso 3 0.07 1.3e-02 -4.7 -5.2 1.6e-07 0.63 0.04 0.54 FALSE
7 GTEx Whole Blood FAM213B 0.06 0.00 lasso 3 0.00 6.5e-01 4.9 5.7 1.3e-08 -0.80 0.02 0.81 FALSE
8 ROSMAP Brain Pre-frontal Cortex RP3-395M20.9 0.06 0.01 blup 367 0.04 5.7e-06 -4.4 -6.2 7.9e-10 0.75 0.08 0.91 TRUE
9 The Cancer Genome Atlas Breast Invasive Carcinoma LOC115110 0.01 0.01 enet 14 0.01 5.2e-04 -5.8 5.5 3.1e-08 -0.71 0.01 0.95 FALSE
10 The Cancer Genome Atlas Breast Invasive Carcinoma MMEL1 0.02 0.02 blup 38 0.03 3.3e-06 -4.3 5.5 4.7e-08 -0.86 0.13 0.86 FALSE
11 The Cancer Genome Atlas Lung Adenocarcinoma MMEL1 0.05 0.03 blup 39 0.05 1.6e-06 -6.1 5.5 3.5e-08 -0.85 0.01 0.99 FALSE
12 The Cancer Genome Atlas Prostate Adenocarcinoma LOC115110 0.03 0.00 blup 50 0.01 1.7e-02 -6.1 5.7 9.4e-09 -0.86 0.01 0.63 FALSE
13 The Cancer Genome Atlas Prostate Adenocarcinoma MMEL1 0.10 0.12 enet 22 0.15 8.5e-16 -4.5 5.6 2.1e-08 -0.83 0.19 0.81 FALSE