218 significantly associated models · 82 unique genes
.
# | chr | p0 | p1 | # assoc genes | # joint genes | best TWAS P | best SNP P | cond SNP P | % var exp | joint genes |
---|---|---|---|---|---|---|---|---|---|---|
1 | 1 | 1781220 | 3219950 | 7 | 1 | 7.9e-10 | 8.0e-10 | 0.02180 | 86 | RP3-395M20.9 |
2 | 1 | 7314655 | 8738937 | 2 | 1 | 3.2e-08 | 2.3e-09 | 0.01850 | 84 | PARK7 |
3 | 1 | 19515061 | 21114833 | 2 | 3 | 1.5e-23 | 4.9e-31 | 0.85300 | 100 | OTUD3 PLA2G5 |
4 | 1 | 160642451 | 162039394 | 3 | 2 | 2.7e-17 | 3.8e-17 | 0.01130 | 91 | FCGR2A RP11-122G18.5 |
5 | 2 | 60466491 | 62087165 | 3 | 1 | 8.9e-11 | 1.8e-12 | 0.00527 | 84 | PEX13 |
6 | 2 | 199443880 | 201021954 | 1 | 1 | 2.6e-07 | 2.3e-07 | 1.00000 | 100 | SATB2 |
7 | 2 | 218382236 | 219846749 | 4 | 1 | 1.0e-08 | 2.0e-07 | 0.20800 | 94 | AAMP |
8 | 3 | 47911521 | 50932324 | 25 | 1 | 2.6e-14 | 2.3e-15 | 1.00000 | 100 | FAM212A |
9 | 4 | 122842267 | 123530993 | 1 | 1 | 1.2e-07 | 3.1e-06 | 0.00931 | 69 | KIAA1109 |
10 | 5 | 131008194 | 132425049 | 1 | 1 | 1.6e-07 | 4.9e-06 | 0.28100 | 94 | SLC22A5 |
11 | 5 | 158501850 | 159005439 | 1 | 1 | 2.3e-08 | 1.1e-09 | 0.01420 | 84 | IL12B |
12 | 6 | 116091635 | 117481404 | 1 | 1 | 2.0e-07 | 6.2e-07 | 0.16100 | 92 | FAM26F |
13 | 7 | 2032803 | 3510741 | 1 | 1 | 1.1e-08 | 1.2e-08 | 0.31500 | 97 | AMZ1 |
14 | 7 | 5726022 | 7141565 | 1 | 1 | 2.0e-07 | 2.3e-05 | 0.82200 | 100 | RAC1 |
15 | 7 | 106847492 | 108340749 | 3 | 1 | 9.9e-16 | 1.7e-15 | 0.00924 | 89 | DLD |
16 | 7 | 127878155 | 129284182 | 1 | 1 | 3.4e-09 | 2.9e-07 | 0.47200 | 98 | IRF5 |
17 | 9 | 138558883 | 140071683 | 6 | 2 | 7.1e-15 | 5.8e-13 | 0.14800 | 96 | CARD9 INPP5E |
18 | 17 | 37137299 | 39048774 | 8 | 1 | 1.9e-10 | 9.2e-12 | 0.00996 | 86 | RAPGEFL1 |
19 | 20 | 61576647 | 62912463 | 6 | 1 | 2.8e-11 | 3.4e-08 | 0.53600 | 99 | RTEL1 |
20 | 21 | 45398656 | 45902320 | 1 | 1 | 2.1e-08 | 7.1e-11 | 0.00027 | 69 | ICOSLG |
21 | 22 | 49656585 | 51055900 | 1 | 1 | 1.6e-07 | 2.4e-08 | 1.00000 | 100 | PIM3 |
Trait | chisq ratio | # genes+ | # genes++ | % genes++ | corr | corr P | genes |
---|
study | tissue | # hits | % hits/tests | avg chisq |
---|
study | tissue | # hits | % hits/tests | avg chisq |
---|---|---|---|---|
GTEx | Whole Blood | 6 | 0.313 | 1.8 |
GTEx | Cells EBV-transformed lymphocytes | 5 | 0.364 | 1.7 |
GTEx | Spleen | 4 | 0.292 | 1.7 |
GTEx | Adrenal Gland | 1 | 0.071 | 1.6 |
GTEx | Artery Coronary | 1 | 0.088 | 1.6 |
GTEx | Brain Cerebellar Hemisphere | 4 | 0.277 | 1.6 |
GTEx | Brain Cortex | 1 | 0.100 | 1.6 |
GTEx | Brain Hypothalamus | 2 | 0.351 | 1.6 |
GTEx | Colon Sigmoid | 1 | 0.071 | 1.6 |
GTEx | Colon Transverse | 3 | 0.151 | 1.6 |
GTEx | Esophagus Mucosa | 4 | 0.125 | 1.6 |
GTEx | Lung | 4 | 0.145 | 1.6 |
GTEx | Ovary | 1 | 0.114 | 1.6 |
GTEx | Pituitary | 0 | 0.000 | 1.6 |
GTEx | Prostate | 1 | 0.124 | 1.6 |
GTEx | Skin Sun Exposed Lower leg | 5 | 0.143 | 1.6 |
GTEx | Uterus | 1 | 0.183 | 1.6 |
GTEx | Vagina | 1 | 0.164 | 1.6 |
NTR | Blood | 9 | 0.378 | 1.6 |
ROSMAP | Brain Pre-frontal Cortex | 7 | 0.164 | 1.6 |
YFS | Blood | 9 | 0.199 | 1.6 |
The Cancer Genome Atlas | Colon Adenocarcinoma | 3 | 0.156 | 1.6 |
The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | 4 | 0.156 | 1.6 |
The Cancer Genome Atlas | Testicular Germ Cell Tumors | 1 | 0.083 | 1.6 |
The Cancer Genome Atlas | Uterine Corpus Endometrial Carcinoma | 1 | 0.211 | 1.6 |
GTEx | Adipose Subcutaneous | 2 | 0.060 | 1.5 |
GTEx | Adipose Visceral Omentum | 5 | 0.254 | 1.5 |
GTEx | Artery Aorta | 2 | 0.070 | 1.5 |
GTEx | Artery Tibial | 5 | 0.139 | 1.5 |
GTEx | Brain Caudate basal ganglia | 0 | 0.000 | 1.5 |
GTEx | Brain Cerebellum | 6 | 0.313 | 1.5 |
GTEx | Brain Frontal Cortex BA9 | 2 | 0.223 | 1.5 |
GTEx | Brain Nucleus accumbens basal ganglia | 1 | 0.119 | 1.5 |
GTEx | Breast Mammary Tissue | 3 | 0.158 | 1.5 |
GTEx | Breast Mammary Tissue (Female) | 2 | 0.129 | 1.5 |
GTEx | Cells Transformed fibroblasts | 6 | 0.148 | 1.5 |
GTEx | Esophagus Gastroesophageal Junction | 0 | 0.000 | 1.5 |
GTEx | Esophagus Muscularis | 7 | 0.225 | 1.5 |
GTEx | Heart Atrial Appendage | 3 | 0.196 | 1.5 |
GTEx | Heart Left Ventricle | 0 | 0.000 | 1.5 |
GTEx | Liver | 0 | 0.000 | 1.5 |
GTEx | Muscle Skeletal | 2 | 0.072 | 1.5 |
GTEx | Nerve Tibial | 6 | 0.144 | 1.5 |
GTEx | Pancreas | 1 | 0.063 | 1.5 |
GTEx | Skin Not Sun Exposed Suprapubic | 3 | 0.126 | 1.5 |
GTEx | Stomach | 1 | 0.072 | 1.5 |
GTEx | Testis | 6 | 0.196 | 1.5 |
GTEx | Thyroid | 4 | 0.104 | 1.5 |
METSIM | Adipose | 6 | 0.134 | 1.5 |
CommonMind | Brain Pre-frontal Cortex | 6 | 0.114 | 1.5 |
The Cancer Genome Atlas | Bladder Urothelial Carcinoma | 2 | 0.129 | 1.5 |
The Cancer Genome Atlas | Breast Invasive Carcinoma | 6 | 0.145 | 1.5 |
The Cancer Genome Atlas | Glioblastoma Multiforme | 1 | 0.105 | 1.5 |
The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | 4 | 0.208 | 1.5 |
The Cancer Genome Atlas | Lung Adenocarcinoma | 6 | 0.218 | 1.5 |
The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | 4 | 0.171 | 1.5 |
The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | 1 | 0.067 | 1.5 |
The Cancer Genome Atlas | Pancreatic Adenocarcinoma | 6 | 0.382 | 1.5 |
The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | 2 | 0.162 | 1.5 |
The Cancer Genome Atlas | Prostate Adenocarcinoma | 6 | 0.138 | 1.5 |
The Cancer Genome Atlas | Rectum Adenocarcinoma | 1 | 0.151 | 1.5 |
The Cancer Genome Atlas | Soft Tissue Sarcoma | 1 | 0.101 | 1.5 |
The Cancer Genome Atlas | Skin Cutaneous Melanoma | 0 | 0.000 | 1.5 |
The Cancer Genome Atlas | Thyroid Carcinoma | 9 | 0.186 | 1.5 |
GTEx | Brain Hippocampus | 0 | 0.000 | 1.4 |
GTEx | Brain Putamen basal ganglia | 0 | 0.000 | 1.4 |
GTEx | Breast Mammary Tissue (Male) | 1 | 0.088 | 1.4 |
GTEx | Small Intestine Terminal Ileum | 0 | 0.000 | 1.4 |
The Cancer Genome Atlas | Cervical Squamous Cell Carcinoma | 0 | 0.000 | 1.4 |
The Cancer Genome Atlas | Esophageal Carcinoma | 1 | 0.155 | 1.4 |
The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | 1 | 0.026 | 1.4 |
The Cancer Genome Atlas | Brain Lower Grade Glioma | 6 | 0.148 | 1.4 |
The Cancer Genome Atlas | Liver Hepatocellular Carcinoma | 1 | 0.096 | 1.4 |
The Cancer Genome Atlas | Stomach Adenocarcinoma | 1 | 0.063 | 1.4 |