Best TWAS P=2.71e-17 · Best GWAS P=3.78e-17 conditioned to 0.0113
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Adipose Visceral Omentum | RP11-122G18.5 | 0.24 | 0.03 | lasso | 14 | 0.08 | 7.4e-05 | 7.4 | -5.3 | 1.3e-07 | -0.18 | 0.58 | 0.10 | TRUE |
2 | The Cancer Genome Atlas | Pancreatic Adenocarcinoma | FCGR2A | 0.17 | 0.08 | enet | 5 | 0.16 | 2.3e-07 | 8.4 | -8.5 | 2.7e-17 | -0.87 | 0.00 | 0.99 | TRUE |
3 | The Cancer Genome Atlas | Pancreatic Adenocarcinoma | FCGR3A | 0.08 | 0.02 | blup | 18 | 0.03 | 3.0e-02 | 2.5 | -7.1 | 9.3e-13 | -0.86 | 0.00 | 0.57 | FALSE |