Best TWAS P=8.91e-11 · Best GWAS P=1.81e-12 conditioned to 0.00527
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Colon Transverse | AC010733.5 | 0.12 | 0.00 | lasso | 6 | 0.00 | 0.445 | 3.1 | -5.4 | 7.3e-08 | -0.77 | 0.02 | 0.75 | FALSE |
2 | GTEx | Nerve Tibial | KIAA1841 | 0.06 | 0.01 | lasso | 4 | 0.02 | 0.015 | -3.1 | -5.3 | 9.7e-08 | -0.54 | 0.26 | 0.50 | FALSE |
3 | The Cancer Genome Atlas | Pancreatic Adenocarcinoma | PEX13 | 0.06 | 0.03 | lasso | 3 | 0.04 | 0.013 | 5.8 | 6.5 | 8.9e-11 | 0.90 | 0.00 | 0.91 | TRUE |