Best TWAS P=4.67e-10 · Best GWAS P=2.96e-09 conditioned to 0.189
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | DCAF16 | 0.10 | 0.01 | enet | 6 | 0.02 | 4.7e-02 | -5.7 | 6.2 | 4.7e-10 | -0.84 | 0.02 | 0.90 | TRUE |
| 2 | GTEx | Breast Mammary Tissue (Male) | DCAF16 | 0.24 | 0.03 | enet | 18 | -0.01 | 4.4e-01 | -5.4 | 5.1 | 2.7e-07 | -0.75 | 0.03 | 0.66 | FALSE |
| 3 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | NCAPG | 0.14 | 0.07 | lasso | 3 | 0.07 | 5.2e-08 | -5.5 | -5.4 | 6.4e-08 | 0.97 | 0.05 | 0.95 | FALSE |
| 4 | The Cancer Genome Atlas | Brain Lower Grade Glioma | DCAF16 | 0.09 | 0.02 | lasso | 3 | 0.04 | 5.2e-05 | 3.7 | 5.6 | 1.9e-08 | -0.70 | 0.14 | 0.64 | FALSE |
| 5 | The Cancer Genome Atlas | Brain Lower Grade Glioma | NCAPG | 0.02 | 0.03 | lasso | 1 | 0.02 | 9.0e-04 | -5.9 | -5.9 | 3.0e-09 | 1.00 | 0.01 | 0.89 | FALSE |
| 6 | The Cancer Genome Atlas | Prostate Adenocarcinoma | DCAF16 | 0.04 | 0.04 | blup | 31 | 0.04 | 2.2e-05 | 3.4 | 5.2 | 1.7e-07 | -0.63 | 0.26 | 0.27 | FALSE |
| 7 | The Cancer Genome Atlas | Thyroid Carcinoma | DCAF16 | 0.07 | 0.04 | blup | 31 | 0.07 | 4.9e-07 | 3.8 | 5.4 | 5.2e-08 | -0.74 | 0.21 | 0.68 | FALSE |