Best TWAS P=2.18e-07 · Best GWAS P=1.95e-06 conditioned to 0.794
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Cells Transformed fibroblasts | NUDT9 | 0.24 | 0.11 | lasso | 6 | 0.11 | 1.5e-08 | 4.7 | 5.2 | 2.2e-07 | 0.94 | 0.01 | 0.98 | TRUE |
2 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | HSD17B11 | 0.05 | 0.02 | enet | 9 | 0.04 | 2.6e-05 | 4.7 | -5.2 | 2.6e-07 | -0.71 | 0.01 | 0.85 | FALSE |