TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Verbal and Numeric Reasoning (VNR)
:
←
→
chr4:87,655,053-89,073,197
Best TWAS P=2.18e-07 · Best GWAS P=1.95e-06 conditioned to 0.794
87.6M
87.8M
88M
88.2M
88.4M
88.6M
88.8M
89M
0
1
2
3
4
5
6
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Cells Transformed fibroblasts
NUDT9
0.24
0.11
lasso
6
0.11
1.5e-08
4.7
5.2
2.2e-07
0.94
0.01
0.98
TRUE
2
The Cancer Genome Atlas
Kidney Renal Clear Cell Carcinoma
HSD17B11
0.05
0.02
enet
9
0.04
2.6e-05
4.7
-5.2
2.6e-07
-0.71
0.01
0.85
FALSE