[Hub]/) : Traits : Verbal and Numeric Reasoning (VNR) :

chr10:102,853,189-104,392,497

Best TWAS P=1.35e-11 · Best GWAS P=1.85e-12 conditioned to 0.00107

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex NPM3 0.03 0.01 lasso 2 0.03 1.2e-04 6.4 -5.5 3.7e-08 0.55 0.12 0.60 FALSE
2 GTEx Pancreas NPM3 0.20 0.15 lasso 4 0.07 5.4e-04 6.3 -5.8 7.0e-09 0.49 0.19 0.62 FALSE
3 GTEx Testis NPM3 0.13 0.15 lasso 3 0.13 2.5e-06 6.3 -6.4 1.6e-10 0.56 0.16 0.77 FALSE
4 ROSMAP Brain Pre-frontal Cortex NPM3 0.05 0.01 blup 257 0.04 1.5e-05 6.2 -5.3 9.0e-08 0.68 0.04 0.91 FALSE
5 The Cancer Genome Atlas Bladder Urothelial Carcinoma GBF1 0.03 0.01 enet 8 0.04 2.1e-04 4.8 -5.4 7.4e-08 0.33 0.03 0.76 TRUE
6 The Cancer Genome Atlas Brain Lower Grade Glioma NPM3 0.02 0.03 lasso 3 0.02 9.2e-04 6.3 -6.8 1.4e-11 0.65 0.01 0.79 TRUE
7 The Cancer Genome Atlas Testicular Germ Cell Tumors C10orf76 0.19 0.20 lasso 1 0.18 4.6e-07 6.3 6.3 2.2e-10 -0.55 0.16 0.80 FALSE