Best TWAS P=2.48e-15 · Best GWAS P=4.48e-16 conditioned to 1.77e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | TNFAIP8 | 0.21 | 0.12 | lasso | 6 | 0.14 | 8.2e-11 | 1.9 | -5.2 | 2.5e-07 | 0.67 | 0.23 | 0.77 | FALSE |
| 2 | GTEx | Uterus | DMXL1 | 0.40 | -0.01 | lasso | 8 | 0.02 | 1.1e-01 | -3.3 | -7.9 | 2.5e-15 | 0.59 | 0.04 | 0.37 | TRUE |
| 3 | The Cancer Genome Atlas | Cervical Squamous Cell Carcinoma | TNFAIP8 | 0.23 | 0.02 | blup | 111 | 0.06 | 4.8e-04 | 5.9 | 5.6 | 1.8e-08 | -0.10 | 0.10 | 0.04 | FALSE |