TWAS hub - DMXL1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Nerve Tibial	0.143	0.0503	0.0012	-0.003	NA	0.009	NA	0.005	0.65	NA	0.073	NA	0.13
2	GTEx	Uterus	0.396	0.1180	0.0024	-0.007	NA	0.001	NA	0.023	0.46	NA	0.310	NA	0.11

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Illnesses of father: High blood pressure	4.7	5.8	11.1	-0.7	-3.3
Blood White Count	4.5	33.2	62.6	-1.9	-7.9
Townsend deprivation index at recruitment	4.4	6.2	9.0	-1.8	-3.0
Medication: Simvastatin	4.3	6.4	11.7	-1.0	-3.4
Unable to work because of sickness or disability	4.3	5.5	9.8	-1.1	-3.1
Medication for cholesterol	4.2	6.4	12.3	0.7	3.5
Medication: Bendroflumethiazide	4.2	6.4	12.6	-0.5	-3.6
High cholesterol (Self-reported)	4.1	7.3	14.3	-0.5	-3.8
Medication: Blood pressure	4.0	7.7	14.7	-0.8	-3.8
High blood pressure (siblings)	3.6	5.2	5.7	-2.2	-2.4
Waist Hip Ratio (WHR)	3.4	15.4	29.7	1.1	-5.5
Peak expiratory flow (PEF)	3.4	7.8	14.1	-1.2	3.8
Cardiovascular Disease	3.3	10.9	21.8	0.1	-4.7
Medication: Atenolol	3.3	4.1	6.0	-1.5	-2.5
Systolic Blood Pressure	3.1	15.6	31.2	-0.2	-5.6
Illnesses of siblings	3.1	4.4	7.7	1.0	2.8
Average weekly spirits intake	3.0	3.7	6.2	1.1	2.5
Eye problems/disorders: None of the above	3.0	3.4	6.1	2.5	0.8
Risk taking	2.9	4.3	6.6	-1.4	-2.6
Medication: Amlodipine	2.8	3.9	4.7	-1.7	-2.2
HDL Cholesterol	2.7	4.5	5.0	2.0	2.2
Rheumatoid Arthritis	2.7	3.8	4.6	-1.7	-2.1
Forced expiratory volume in 1-second (FEV1), Best measure	2.7	8.5	14.7	1.5	3.8
Ever had stillbirth, spontaneous miscarriage or termination	2.7	2.9	4.7	-1.0	-2.2
Medication: Blood pressure	2.6	4.6	6.9	-1.5	-2.6
Chest pain or discomfort	2.6	3.8	7.5	0.0	-2.7
Illnesses of father: None of the above (group 1)	2.6	3.2	4.9	1.2	2.2
Forced vital capacity (FVC), Best measure	2.4	8.9	15.7	1.5	4.0
Type 2 Diabetes (T2D) (2018)	2.3	4.4	8.7	0.1	-3.0
Medication: Co-codamol	2.3	2.6	4.4	2.1	0.9
Frequency of unenthusiasm / disinterest in last 2 weeks	2.3	3.0	3.5	-1.6	-1.9
Triglycerides	2.1	3.4	4.1	-2.0	-1.7
Allergy	2.1	4.9	8.8	1.0	3.0
Reason for reducing amount of alcohol drunk: Health precaution	2.1	2.5	5.0	2.2	0.0
Number of self-reported non-cancer illnesses	2.1	3.7	7.2	0.4	-2.7
Schizophrenia vs Biploar Disorder	2.0	2.6	5.2	-0.2	2.3
High blood pressure	2.0	5.5	9.5	-1.3	-3.1
Health satisfaction	2.0	2.6	4.4	-0.9	-2.1
Heart disease (mother)	2.0	2.4	3.4	-1.8	-1.2
Hypertension (Self-reported)	2.0	5.5	10.5	-0.7	-3.2
Tinnitus: Yes, now most or all of the time	2.0	2.4	3.6	-1.9	-1.1
Financial difficulties in last 2 years	1.9	2.6	5.0	-0.4	-2.2
Forced expiratory volume in 1-second (FEV1)	1.9	6.5	12.3	0.8	3.5
Ever highly irritable/argumentative for 2 days	1.9	2.3	2.3	-1.5	-1.5
Friendships satisfaction	1.9	2.4	4.2	0.8	-2.0
Medication: Paracetamol	1.9	2.9	5.6	0.3	-2.4
Alcohol drinker status: Previous	1.9	2.2	3.9	-0.7	-2.0
Number of treatments/medications taken	1.8	3.3	6.5	0.3	-2.5
Frequency of depressed mood in last 2 weeks	1.8	2.5	4.4	-0.8	-2.1
Hayfever, allergic rhinitis or eczema	1.8	3.9	7.5	-0.6	-2.7
Forced vital capacity (FVC)	1.8	7.0	13.6	0.5	3.7
Diabetes (self-reported)	1.8	2.7	4.2	-1.1	-2.1
Happiness	1.8	2.2	2.7	-1.3	-1.6
Medication for cholesterol, blood pressure or diabetes	1.8	3.0	5.0	1.0	2.2
Age at last live birth	1.8	2.6	4.5	0.8	2.1
High blood pressure (mother)	1.7	2.4	3.8	-1.0	-1.9
Loneliness, isolation	1.7	2.4	3.4	-1.9	-1.1
Cholesterol lowering medication	1.7	2.5	4.8	-0.5	-2.2
Systolic blood pressure, automated reading	1.6	4.8	9.0	-0.7	-3.0
Ever unenthusiastic/disinterested for a whole week	1.6	1.9	2.7	-1.6	-1.0
Worrier / anxious feelings	1.6	3.1	3.6	1.9	1.6
Medication: Cholesterol lowering	1.6	2.5	5.1	0.0	-2.2
Illnesses of mother	1.6	2.0	2.1	-1.4	1.4
Osteoarthritis (self-reported)	1.6	2.0	3.3	-0.8	-1.8
Diastolic blood pressure, automated reading	1.6	5.0	7.9	-1.5	-2.8
Body Mass Index (BMI) (2010)	1.5	2.0	2.1	-1.4	-1.5
Average weekly fortified wine intake	1.5	1.7	3.4	-1.8	-0.3
Lung cancer (father)	1.5	1.7	3.3	0.3	1.8
Age at first live birth	1.5	2.6	5.2	0.3	2.3
Commuting to job workplace: Public transport	1.5	1.8	2.2	-1.2	-1.5
Heart disease (siblings)	1.5	1.9	3.7	-0.3	-1.9
Lung FVC	1.4	7.2	13.4	1.0	3.7
Diabetes (father)	1.4	1.7	2.2	-1.1	-1.5
Frequency of tiredness / lethargy in last 2 weeks	1.4	2.3	3.2	-1.2	-1.8
Asthma	1.4	2.7	3.9	-2.0	-1.2
Prospective memory result	1.4	1.7	3.2	1.8	0.4
Hypothyroidism/myxoedema (self-reported)	1.4	2.8	5.3	-0.5	-2.3
Medication: Ventolin 100micrograms inhaler	1.4	1.9	2.0	-1.3	-1.4
Mean time to correctly identify matches	1.4	2.6	4.3	2.1	1.0
Leg pain on walking	1.4	1.8	2.7	-0.9	-1.6
Breast cancer (self-reported)	1.4	1.7	3.3	1.8	0.3
Medication: Gliclazide	1.4	1.6	2.6	-1.6	-0.8
Reaction Time	1.3	2.4	4.5	2.1	0.5
Coronary Artery Disease (CAD)	1.3	1.6	2.9	-0.5	-1.7
Allergy or Eczema	1.3	3.4	6.2	-0.8	-2.5
Number of incorrect matches in round	1.3	2.1	2.6	1.6	1.3
Mouth/teeth dental problems: Dentures	1.3	2.2	3.8	0.7	1.9
Seen doctor (GP) for nerves, anxiety, tension or depression	1.3	2.0	4.0	2.0	0.3
Illness, injury, bereavement, stress in last 2 years	1.3	1.6	3.2	0.0	1.8
Diabetes diagnosed by doctor	1.3	2.1	3.0	-1.1	-1.7
Mother’s age at death	1.3	1.6	2.7	1.6	0.8
Pain type(s) experienced in last month: Hip pain	1.3	1.6	2.6	-0.8	-1.6
Vascular/heart problems diagnosed by doctor	1.3	3.5	6.1	1.0	2.5
Bipolar Disorder (2018)	1.2	1.9	3.2	-1.8	-0.8
Eye problems/disorders: Diabetes related eye disease	1.2	1.3	1.5	1.2	-1.1
Taking other prescription medications	1.2	1.8	1.9	1.4	-1.3
Impedance of arm (right)	1.2	5.6	10.8	3.3	0.6
Chronic bronchitis/emphysema (mother)	1.2	1.4	2.4	1.6	0.6
Neck or shoulder pain in last month	1.2	1.7	3.3	-1.8	-0.2
Migraine (self-reported)	1.2	1.5	2.7	-0.5	-1.7
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.2	1.4	2.6	-1.6	-0.4
Knee pain experienced in last month	1.2	1.8	1.9	-1.4	-1.3
Average weekly beer plus cider intake	1.2	1.7	3.4	-0.1	-1.8
Mean Putamen Volume	1.1	1.2	2.3	-0.4	-1.5
Schizophrenia (2014)	1.1	2.5	2.6	-1.6	1.6
Bilateral oophorectomy (both ovaries removed)	1.1	1.3	2.1	0.7	-1.4
Stomach or abdominal pain in last month	1.1	1.3	2.4	0.6	-1.5
Hayfever/allergic rhinitis (self-reported)	1.1	1.5	2.9	-0.2	-1.7
Impedance of arm (left)	1.1	5.0	9.9	3.1	-0.0
Glaucoma (self-reported)	1.1	1.3	1.3	-1.2	-1.1
Smoking status: Previous	1.1	1.6	3.2	-0.0	1.8
Asthma (self-reported)	1.1	2.1	3.4	-1.8	-0.9
Miserableness	1.1	2.0	2.1	-1.4	-1.4
Depression (Nagel 2018)	1.0	1.5	2.9	0.5	-1.7
Other serious medical condition/disability diagnosed by doctor	1.0	1.3	2.4	0.4	-1.5
Father’s age at death	1.0	1.3	2.5	-0.4	1.6
Overall health rating	1.0	2.2	3.9	0.6	-2.0
Eye problems/disorders: Cataract	1.0	1.1	1.7	-1.3	-0.7
Guilty feelings	1.0	1.5	2.9	-1.7	0.2
Irritability	1.0	1.6	2.6	0.8	1.6
Medication: Omeprazole (e.g. Zanprol)	1.0	1.2	2.5	-0.0	-1.6
Lupus	0.9	1.4	2.5	-1.6	0.5
Severe depression (siblings)	0.9	1.0	1.9	1.4	-0.5
Impedance of leg (right)	0.9	4.2	7.1	2.7	-1.1
Qualifications: CSEs or equivalent	0.9	1.2	1.4	-1.2	1.0
Medication: Omeprazole	0.9	1.0	2.0	-0.2	-1.4
Number of full sisters	0.9	1.1	2.2	-1.5	0.0
Suffer from ‘nerves’	0.9	1.5	2.3	-1.5	0.8
Illnesses of father: Heart disease	0.9	1.3	2.6	-0.1	-1.6
Ever had bowel cancer screening	0.9	1.0	1.6	0.7	1.3
Financial situation satisfaction	0.9	1.1	2.1	-0.2	-1.4
Eye problems/disorders: Glaucoma	0.9	1.0	1.6	-0.7	-1.2
Ever had prostate specific antigen (PSA) test	0.9	1.0	2.0	-0.1	1.4
Impedance of whole body	0.9	4.7	9.5	3.1	0.1
Schizophrenia (2018)	0.8	1.6	3.2	0.0	1.8
LDL Cholesterol	0.8	1.3	2.3	0.6	-1.5
Hypothyroidism (self reported)	0.8	1.8	3.3	0.5	-1.8
Vitamin and mineral supplements	0.8	1.0	2.1	-0.0	1.4
Medication: Metformin	0.8	1.1	1.4	-0.9	-1.2
Tinnitus: Yes, but not now, but have in the past	0.8	0.8	1.6	0.0	-1.3
Impedance of leg (left)	0.8	4.0	8.0	2.8	-0.1
Mouth/teeth dental problems	0.8	1.3	1.5	-1.2	-1.0
Number of live births	0.8	1.1	2.2	-1.5	-0.2
Noisy workplace	0.8	0.9	1.8	0.2	1.4
Depression (self-reported)	0.8	1.0	1.7	0.4	-1.3
Medication: Allopurinol	0.8	1.0	1.7	1.3	0.6
Smoking status: Current	0.8	1.3	2.3	-0.6	-1.5
Supplements: Fish oil (including cod liver oil)	0.8	1.0	2.0	-1.4	-0.1
Myopia	0.8	1.1	1.2	-1.1	-1.0
Major Depression (MDD)	0.7	0.8	1.3	1.2	-0.5
Age at First Birth	0.7	1.0	1.8	1.3	0.6
Hearing difficulty/problems: Yes	0.7	1.0	2.1	-0.2	-1.4
Current tobacco smoking	0.7	1.1	1.7	-0.8	-1.3
Heel bone mineral density (BMD) T-score, automated (left)	0.7	1.6	1.9	1.4	1.1
Multivitamins +/- minerals	0.7	0.8	1.7	-0.1	-1.3
Sitting height	0.7	4.8	7.8	1.3	2.8
Pain all over the body in last month	0.7	0.8	1.2	-1.1	-0.6
Hip circumference	0.7	3.0	6.0	0.1	2.4
Hair/balding pattern: Pattern 3	0.7	1.0	1.4	-0.8	1.2
Medication: Ibuprofen (e.g. Nurofen)	0.7	0.8	1.2	-1.1	0.7
Birth weight	0.7	1.5	2.8	1.7	-0.6
Family relationship satisfaction	0.7	0.9	1.7	-0.3	-1.3
Commuting to job workplace: Car/motor vehicle	0.7	0.8	1.6	-0.0	1.2
Long-standing illness, disability or infirmity	0.7	1.1	1.9	0.6	-1.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.7	1.4	2.6	-0.4	1.6
Average weekly champagne plus white wine intake	0.7	1.0	2.0	-1.4	-0.2
Ever taken oral contraceptive pill	0.7	0.8	1.1	-0.7	1.0
Worry (Nagel 2018)	0.6	1.3	2.1	0.7	1.5
Hand grip strength (right)	0.6	1.7	3.2	-0.5	1.8
Number of full brothers	0.6	0.8	0.8	0.8	-0.9
Wheeze or whistling in the chest in last year	0.6	1.0	1.6	-1.3	-0.7
Mouth/teeth dental problems: Loose teeth	0.6	0.7	0.7	0.8	-0.9
Pulse rate, automated reading	0.6	2.0	3.9	-0.2	-2.0
Fractured/broken bones in last 5 years	0.6	0.8	1.4	-0.3	1.2
Intelligence (Savage-Jansen 2018)	0.5	1.4	2.0	-1.4	-0.9
Neuroticism (2016)	0.5	0.8	1.5	0.2	-1.2
Lung FEV1/FVC ratio	0.5	2.7	3.3	1.8	-1.5
Sensitivity / hurt feelings	0.5	0.9	1.6	-0.3	1.3
Relative age of first facial hair	0.5	1.0	1.3	1.1	0.9
Chronic bronchitis/emphysema (father)	0.5	0.6	0.8	-0.9	0.7
Past tobacco smoking	0.5	0.9	1.6	0.4	-1.3
Qualifications: None of the above	0.5	1.0	1.6	0.7	1.3
Time employed in main current job	0.5	0.5	0.7	0.6	-0.8
Breastfed as a baby	0.5	0.6	1.0	1.0	0.6
Hair/balding pattern: Pattern 4	0.5	1.2	1.9	0.6	1.4
Medication: Paracetamol	0.5	0.9	1.7	0.1	-1.3
Gout (self-reported)	0.5	0.7	1.1	1.1	0.5
Medication: Seretide 50 evohaler	0.5	0.6	1.2	-0.2	1.1
Supplements: Vitamin C	0.5	0.6	0.8	0.9	0.6
Qualifications: nursing, teaching	0.5	0.8	1.6	0.3	1.3
Ever depressed for a whole week	0.5	0.6	1.1	-0.3	1.1
Bipolar Disorder or Schizophrenia	0.4	1.1	1.4	-1.2	0.9
Crohns Disease (2012)	0.4	0.6	0.9	0.5	0.9
HbA1C	0.4	0.5	1.0	1.0	-0.1
Hand grip strength (left)	0.4	0.9	1.0	-0.9	1.0
Supplements: Glucosamine	0.4	0.5	0.9	-0.4	0.9
Medication: Levothyroxine sodium	0.4	0.6	1.2	-0.2	-1.1
Body mass index (BMI)	0.4	1.5	2.4	-1.6	0.8
Had menopause	0.4	0.5	0.6	0.8	-0.6
Had other major operations	0.4	0.5	0.7	0.6	-0.8
Medication: Ramipril	0.4	0.6	0.7	0.7	-0.8
Neuroticism score	0.4	0.8	0.9	-1.0	0.8
Serious illness, injury or assault of a close relative in last 2 years	0.4	0.4	0.7	-0.4	-0.8
Standing height	0.4	3.6	5.3	2.3	1.3
Length of working week for main job	0.4	0.5	0.6	-0.8	0.5
Pulse wave peak to peak time	0.4	0.5	0.7	0.4	0.9
Medication for pain relief, constipation, heartburn	0.4	0.6	1.0	0.4	1.0
Medication: Ibuprofen	0.4	0.4	0.5	-0.6	0.7
Comparative height size at age 10	0.4	2.3	3.9	2.0	-0.8
Had major operations	0.4	0.4	0.8	0.9	0.3
Leg fat-free mass (right)	0.4	2.2	2.8	-1.2	1.7
Commuting to job workplace: Walk	0.4	0.4	0.5	-0.6	-0.7
Back pain experienced in last month	0.4	0.5	0.8	-0.9	-0.5
Mineral and other dietary supplements	0.4	0.5	0.6	0.7	-0.8
Leg predicted mass (right)	0.4	2.1	2.8	-1.2	1.7
Neuroticism (Nagel 2018)	0.3	0.7	1.1	0.6	1.1
Alzheimer’s Disease (in mother)	0.3	0.4	0.6	0.3	0.8
Ovarian Cancer	0.3	0.3	0.6	0.8	0.3
Bipolar Disorder (2011)	0.3	0.3	0.4	-0.7	0.5
Blood Eosinophil Count	0.3	2.3	3.1	-1.2	-1.8
BMI	0.3	1.6	2.1	-1.0	1.4
Chronotype (morning person)	0.3	0.7	1.3	-1.1	-0.3
Ever used hormone-replacement therapy (HRT)	0.3	0.3	0.4	0.6	-0.6
Angina	0.3	0.3	0.6	0.8	-0.2
Supplements: Zinc	0.3	0.4	0.7	0.8	-0.3
Diabetes (mother)	0.3	0.3	0.6	0.8	-0.2
Leg fat-free mass (left)	0.3	1.3	1.4	-1.2	1.1
Maternal smoking around birth	0.3	0.4	0.7	-0.8	-0.3
Relative age voice broke	0.3	0.5	1.0	-1.0	0.0
Age when periods started (menarche)	0.3	0.6	1.1	0.4	1.1
Alcohol usually taken with meals	0.3	0.5	0.8	-0.4	0.9
Nervous feelings	0.3	0.6	1.1	0.2	1.1
Frequency of tenseness / restlessness in last 2 weeks	0.3	0.5	0.6	-0.7	-0.8
Pulse rate	0.3	0.5	0.7	-0.8	-0.6
Qualifications: A levels/AS levels or equivalent	0.3	0.6	1.0	0.4	-1.0
Medication: Lansoprazole	0.3	0.3	0.5	0.3	0.7
Tense / ‘highly strung’	0.3	0.4	0.7	0.5	0.8
Birth weight of first child	0.3	0.5	0.9	0.3	0.9
Mouth/teeth dental problems: Bleeding gums	0.3	0.4	0.7	0.0	-0.9
Qualifications: College or University degree	0.3	1.0	1.2	1.1	-0.9
Osteoporosis (self-reported)	0.3	0.4	0.7	-0.8	-0.3
Wears glasses or contact lenses	0.3	0.4	0.7	0.8	-0.0
Hearing aid user	0.3	0.4	0.6	0.4	-0.8
Medication: Atorvastatin	0.3	0.4	0.8	0.3	0.9
Arm fat-free mass (left)	0.3	1.5	1.9	-1.0	1.4
Supplements: Calcium	0.3	0.4	0.5	-0.7	-0.5
Alzheimer’s Disease (in father)	0.2	0.2	0.3	0.2	0.6
Crohns Disease (2017)	0.2	0.4	0.7	0.4	0.8
Breast Cancer	0.2	0.4	0.4	0.6	0.6
Primary Biliary Cirrhosis	0.2	0.3	0.7	0.8	0.1
Type 2 Diabetes (T2D) (2012)	0.2	0.2	0.4	-0.2	-0.6
Blood Platelet Count	0.2	2.0	3.3	-0.8	-1.8
Respiratory disease	0.2	0.5	0.7	-0.8	0.6
Neuroticism	0.2	0.5	0.7	-0.6	0.8
Trunk fat percentage	0.2	1.0	1.7	0.5	1.3
Diverticular disease/diverticulitis (self-reported)	0.2	0.2	0.5	-0.1	0.7
Leg predicted mass (left)	0.2	1.3	1.5	-1.2	1.1
Trunk fat mass	0.2	0.8	1.6	0.2	1.3
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.5	1.0	1.0	0.3
Fluid intelligence score	0.2	0.4	0.6	-0.8	-0.5
Weight	0.2	1.1	2.0	-0.4	1.4
Falls in the last year	0.2	0.3	0.4	0.5	0.6
Pulse wave Arterial Stiffness index	0.2	0.2	0.3	-0.3	-0.6
Pulse wave reflection index	0.2	0.3	0.3	-0.5	0.6
Loud music exposure frequency	0.2	0.2	0.3	-0.5	-0.3
Qualifications: O levels/GCSEs or equivalent	0.2	0.3	0.5	0.2	0.7
Blood clot in the leg (DVT)	0.2	0.3	0.6	-0.1	-0.8
Exposure to tobacco smoke outside home	0.2	0.3	0.4	-0.6	-0.4
Comparative body size at age 10	0.2	0.4	0.4	-0.6	-0.7
Seen a psychiatrist for nerves, anxiety, tension or depression	0.2	0.3	0.6	0.0	-0.8
Shortness of breath walking on level ground	0.2	0.3	0.5	-0.7	-0.0
Arm predicted mass (right)	0.2	1.1	1.3	-1.1	1.0
Medication: Aspirin	0.2	0.3	0.4	0.3	-0.7
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.2	0.3	0.3	0.5	-0.5
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.4	0.7	-0.8	0.4
Whole body fat-free mass	0.2	1.0	1.0	-1.0	1.0
Mouth/teeth dental problems: Mouth ulcers	0.2	0.3	0.7	0.2	-0.8
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.2	0.3	0.4	-0.6	0.4
Medication: Aspirin	0.2	0.3	0.6	0.2	-0.8
Whole body water mass	0.2	1.0	1.1	-1.0	0.9
Ever smoked	0.2	0.3	0.6	-0.0	0.8
Basal metabolic rate	0.2	1.1	1.3	-0.9	1.1
Age started oral contraceptive pill	0.2	0.3	0.5	0.7	0.4
Pain experienced in last month	0.2	0.3	0.7	0.8	0.1
Basal cell carcinoma (self-reported)	0.2	0.2	0.2	0.5	-0.4
Deep venous thrombosis (DVT) (self-reported)	0.2	0.2	0.4	0.0	-0.7
Leg fat mass (left)	0.2	0.6	0.8	-0.7	0.9
Arm predicted mass (left)	0.2	1.0	1.4	-0.7	1.2
Alzheimer’s Disease (including proxy)	0.1	0.1	0.2	0.3	0.5
Irritable Bowel Disease (IBD)	0.1	0.4	0.6	0.4	0.8
Ulcerative Colitis	0.1	0.2	0.3	-0.6	0.1
Height	0.1	2.3	2.5	1.6	1.4
Smoking Status	0.1	0.3	0.4	-0.5	0.7
Tanning	0.1	0.7	1.3	0.3	1.1
Ever had hysterectomy (womb removed)	0.1	0.2	0.3	0.5	0.2
Medication for hormone replacement therapy	0.1	0.1	0.1	0.2	-0.3
Fed-up feelings	0.1	0.2	0.2	-0.5	-0.4
Serious illness, injury or assault to yourself	0.1	0.1	0.2	0.4	-0.3
Hearing difficulty/problems with background noise	0.1	0.2	0.4	0.1	-0.6
Heart attack	0.1	0.1	0.1	0.2	0.4
Arm fat percentage (right)	0.1	0.2	0.4	-0.2	0.7
Trunk fat-free mass	0.1	0.5	0.8	-0.9	0.6
Alcohol intake versus 10 years previously	0.1	0.2	0.3	0.2	0.6
Arm fat mass (right)	0.1	0.4	0.5	-0.5	0.7
Trunk predicted mass	0.1	0.5	0.7	-0.9	0.5
Exposure to tobacco smoke at home	0.1	0.1	0.1	0.4	-0.2
Headache pain in last month	0.1	0.1	0.3	0.5	-0.0
Body fat percentage	0.1	0.4	0.8	0.2	0.9
Arm fat-free mass (right)	0.1	0.8	0.9	-0.9	0.8
Worry too long after embarrassment	0.1	0.1	0.2	-0.4	-0.2
Whole body fat mass	0.1	0.5	0.9	-0.1	1.0
Leg fat mass (right)	0.1	0.5	0.5	-0.6	0.7
Illnesses of siblings: Diabetes	0.1	0.1	0.2	-0.1	-0.4
Average weekly red wine intake	0.1	0.1	0.2	-0.5	0.3
Handedness (chirality/laterality): Left-handed	0.1	0.1	0.3	-0.5	0.0
Arm fat mass (left)	0.1	0.4	0.4	-0.7	0.6
Alcohol drinker status: Never	0.1	0.1	0.1	0.2	0.4
Leg fat percentage (left)	0.1	0.2	0.5	-0.2	0.7
Number of operations (self-reported)	0.1	0.2	0.2	0.5	-0.3
Depressed Affect (Nagel 2018)	0.0	0.1	0.1	0.3	-0.2
Ulcerative Colitis (UC)	0.0	0.0	0.0	-0.1	0.1
Verbal and Numeric Reasoning (VNR)	0.0	0.0	0.1	-0.3	0.1
Prostate Cancer	0.0	0.0	0.0	-0.0	-0.2
Fasting Glucose	0.0	0.0	0.0	0.0	0.2
Blood Red Count	0.0	0.2	0.4	0.7	0.0
Heel T-Score	0.0	0.0	0.0	-0.2	-0.0
Hair Pigment	0.0	0.4	0.4	0.7	0.7
Pack years adult smoking proportion	0.0	0.0	0.1	0.2	-0.2
Waist circumference	0.0	0.1	0.1	-0.1	-0.4
Hair/balding pattern: Pattern 2	0.0	0.0	0.0	0.2	0.1
Leg fat percentage (right)	0.0	0.0	0.0	-0.1	0.2
Number of children fathered	0.0	0.0	0.1	-0.0	-0.2
Emphysema/chronic bronchitis	0.0	0.0	0.0	0.2	0.0
Angina (self-reported)	0.0	0.0	0.1	0.3	-0.0
Alcohol intake frequency.	0.0	0.0	0.0	0.1	-0.2
Qualifications: NVQ or HND or HNC or equivalent	0.0	0.0	0.0	-0.1	0.1
Arm fat percentage (left)	0.0	0.1	0.1	-0.3	0.3
Mood swings	0.0	0.1	0.1	0.3	0.1
Medication: Lisinopril	0.0	0.0	0.0	-0.2	-0.2
Commuting to job workplace: Cycle	0.0	0.0	0.0	0.2	-0.1
Heart attack/myocardial infarction (self-reported)	0.0	0.0	0.0	0.2	0.1
Pack years of smoking	0.0	0.0	0.1	0.2	0.0

Hub : Genes

DMXL1

Models

Trait associations