Best TWAS P=2.7e-08 · Best GWAS P=5.24e-08 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | CTC-228N24.3 | 0.24 | 0.15 | enet | 16 | 0.20 | 3.4e-16 | -5.4 | 5.4 | 6.2e-08 | -0.97 | 0.00 | 1.00 | FALSE |
| 2 | GTEx | Artery Aorta | CTC-228N24.3 | 0.20 | 0.04 | lasso | 8 | 0.07 | 7.4e-05 | -1.3 | 5.2 | 1.8e-07 | -0.91 | 0.06 | 0.90 | FALSE |
| 3 | GTEx | Artery Tibial | CTC-228N24.3 | 0.20 | 0.16 | lasso | 7 | 0.14 | 3.0e-11 | -5.4 | 5.3 | 9.0e-08 | -0.99 | 0.00 | 1.00 | FALSE |
| 4 | GTEx | Heart Atrial Appendage | CTC-228N24.3 | 0.22 | 0.07 | lasso | 5 | 0.07 | 4.1e-04 | -5.2 | 5.2 | 2.2e-07 | -0.87 | 0.00 | 0.99 | FALSE |
| 5 | GTEx | Lung | CTC-228N24.3 | 0.18 | 0.14 | enet | 16 | 0.14 | 3.2e-11 | -5.4 | 5.3 | 9.4e-08 | -0.95 | 0.00 | 1.00 | FALSE |
| 6 | GTEx | Muscle Skeletal | CTC-228N24.3 | 0.25 | 0.20 | lasso | 5 | 0.21 | 1.6e-20 | -5.4 | 5.4 | 7.1e-08 | -0.95 | 0.00 | 1.00 | FALSE |
| 7 | GTEx | Nerve Tibial | CTC-228N24.3 | 0.32 | 0.18 | lasso | 10 | 0.16 | 1.6e-11 | -5.3 | 5.2 | 2.4e-07 | -0.96 | 0.00 | 1.00 | FALSE |
| 8 | GTEx | Pancreas | CTC-228N24.3 | 0.14 | 0.19 | lasso | 2 | 0.17 | 1.1e-07 | -5.4 | 5.4 | 5.7e-08 | -1.00 | 0.00 | 1.00 | FALSE |
| 9 | METSIM | Adipose | CTC-228N24.3 | 0.17 | 0.19 | lasso | 6 | 0.18 | 1.9e-26 | -5.4 | 5.4 | 5.5e-08 | -1.00 | 0.00 | 1.00 | FALSE |
| 10 | The Cancer Genome Atlas | Glioblastoma Multiforme | FLJ33630 | 0.38 | 0.20 | lasso | 5 | 0.17 | 6.5e-06 | -5.4 | 5.5 | 5.0e-08 | -0.99 | 0.00 | 0.99 | FALSE |
| 11 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | FLJ33630 | 0.10 | 0.07 | lasso | 3 | 0.08 | 7.0e-09 | -5.3 | 5.2 | 1.8e-07 | -0.95 | 0.00 | 1.00 | FALSE |
| 12 | The Cancer Genome Atlas | Brain Lower Grade Glioma | FLJ33630 | 0.19 | 0.16 | enet | 4 | 0.16 | 1.2e-17 | -5.4 | 5.4 | 5.4e-08 | -1.00 | 0.00 | 1.00 | FALSE |
| 13 | The Cancer Genome Atlas | Lung Adenocarcinoma | FLJ33630 | 0.07 | 0.05 | lasso | 1 | 0.04 | 1.3e-05 | -5.3 | 5.3 | 1.2e-07 | -0.96 | 0.00 | 0.99 | FALSE |
| 14 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | FLJ33630 | 0.09 | 0.08 | lasso | 4 | 0.09 | 4.9e-10 | -5.4 | 5.4 | 5.8e-08 | -1.00 | 0.00 | 1.00 | FALSE |
| 15 | The Cancer Genome Atlas | Prostate Adenocarcinoma | FLJ33630 | 0.08 | 0.05 | blup | 70 | 0.04 | 4.4e-05 | -5.3 | 5.1 | 2.8e-07 | -0.86 | 0.00 | 1.00 | FALSE |
| 16 | The Cancer Genome Atlas | Testicular Germ Cell Tumors | FLJ33630 | 0.26 | 0.14 | lasso | 3 | 0.13 | 2.2e-05 | -5.4 | 5.6 | 2.7e-08 | -0.99 | 0.00 | 0.99 | TRUE |
| 17 | The Cancer Genome Atlas | Thyroid Carcinoma | FLJ33630 | 0.10 | 0.10 | lasso | 2 | 0.09 | 5.3e-09 | -5.4 | 5.4 | 7.6e-08 | -1.00 | 0.00 | 1.00 | FALSE |