Best TWAS P=5.67e-08 · Best GWAS P=8.08e-09 conditioned to 0.0233
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | ROSMAP | Brain Pre-frontal Cortex | RP11-361F15.2 | 0.05 | 0.06 | lasso | 4 | 0.05 | 1.8e-07 | -5.3 | 5.2 | 1.7e-07 | -0.91 | 0.02 | 0.98 | FALSE |
| 2 | YFS | Blood | STXBP5 | 0.07 | 0.04 | lasso | 5 | 0.05 | 4.6e-15 | 5.0 | 5.4 | 5.7e-08 | -0.83 | 0.07 | 0.92 | TRUE |