Best TWAS P=9.47e-19 · Best GWAS P=9.45e-19 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | TULP4 | 0.16 | 0.08 | bslmm | 596 | 0.12 | 2.9e-14 | 5.15 | 5.1 | 2.9e-07 | -0.01 | 1.00 | 0.00 | FALSE |
| 2 | GTEx | Brain Cortex | TMEM181 | 0.32 | -0.01 | enet | 72 | 0.04 | 2.8e-02 | 0.73 | -5.2 | 2.4e-07 | -0.17 | 0.07 | 0.05 | TRUE |
| 3 | GTEx | Thyroid | TULP4 | 0.09 | 0.02 | lasso | 4 | 0.03 | 1.4e-03 | -5.08 | -5.9 | 2.8e-09 | 0.02 | 0.17 | 0.03 | TRUE |
| 4 | NTR | Blood | TAGAP | 0.05 | 0.04 | bslmm | 566 | 0.04 | 2.1e-13 | 8.84 | -8.8 | 9.5e-19 | -0.99 | 0.00 | 1.00 | TRUE |
| 5 | YFS | Blood | TAGAP | 0.09 | 0.07 | bslmm | 552 | 0.07 | 1.4e-21 | 8.84 | -8.6 | 9.9e-18 | -0.98 | 0.00 | 1.00 | FALSE |
| 6 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | TULP4 | 0.09 | 0.05 | blup | 148 | 0.04 | 2.0e-05 | -3.22 | 5.8 | 7.0e-09 | -0.06 | 0.64 | 0.06 | FALSE |