Best TWAS P=1.57e-08 · Best GWAS P=4.18e-09 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Cancer Genome Atlas | Lung Adenocarcinoma | PARP12 | 0.02 | 0.01 | blup | 68 | 0.01 | 2.4e-02 | -5.9 | 5.5 | 3.7e-08 | -0.88 | 0.01 | 0.95 | FALSE |
| 2 | The Cancer Genome Atlas | Prostate Adenocarcinoma | PARP12 | 0.06 | 0.04 | lasso | 2 | 0.04 | 1.3e-04 | -5.9 | -5.7 | 1.6e-08 | 0.97 | 0.00 | 0.99 | TRUE |
| 3 | The Cancer Genome Atlas | Thyroid Carcinoma | PARP12 | 0.14 | 0.11 | enet | 10 | 0.12 | 9.4e-12 | -5.7 | 5.5 | 5.1e-08 | -0.91 | 0.01 | 0.99 | FALSE |