Best TWAS P=3.76e-10 · Best GWAS P=4.27e-10 conditioned to 0.0617
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Visceral Omentum | ZFAND4 | 0.19 | 0.11 | enet | 6 | 0.10 | 5.6e-06 | 5.6 | -5.2 | 2.4e-07 | -0.76 | 0.08 | 0.91 | FALSE |
| 2 | GTEx | Adrenal Gland | ALOX5 | 0.23 | 0.07 | lasso | 7 | 0.04 | 1.6e-02 | 5.6 | -5.5 | 4.4e-08 | -0.74 | 0.04 | 0.68 | FALSE |
| 3 | GTEx | Artery Tibial | ZFAND4 | 0.06 | 0.00 | enet | 6 | 0.00 | 3.4e-01 | 5.5 | -5.6 | 2.6e-08 | -0.72 | 0.05 | 0.37 | FALSE |
| 4 | GTEx | Brain Cerebellar Hemisphere | MARCH8 | 0.25 | 0.19 | lasso | 5 | 0.23 | 1.3e-06 | 5.0 | 6.2 | 7.4e-10 | 0.88 | 0.01 | 0.98 | FALSE |
| 5 | GTEx | Brain Cerebellum | MARCH8 | 0.17 | 0.03 | enet | 13 | 0.10 | 9.1e-04 | 4.7 | 5.6 | 1.7e-08 | 0.68 | 0.03 | 0.73 | FALSE |
| 6 | GTEx | Cells Transformed fibroblasts | ZFAND4 | 0.24 | 0.22 | lasso | 9 | 0.24 | 4.3e-18 | 5.6 | -5.6 | 2.1e-08 | -0.80 | 0.08 | 0.92 | FALSE |
| 7 | GTEx | Nerve Tibial | ALOX5 | 0.11 | 0.03 | lasso | 6 | 0.04 | 1.0e-03 | 6.2 | -5.3 | 1.4e-07 | -0.88 | 0.00 | 0.98 | FALSE |
| 8 | GTEx | Nerve Tibial | ZFAND4 | 0.05 | 0.02 | lasso | 5 | 0.03 | 6.1e-03 | 5.5 | -6.3 | 3.8e-10 | -0.83 | 0.02 | 0.95 | TRUE |