Best TWAS P=5.26e-23 · Best GWAS P=6.18e-26 conditioned to 5.5e-09
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Colon Sigmoid | FLT1 | 0.39 | 0.05 | lasso | 9 | 0.05 | 9.2e-03 | -9.2 | -9.9 | 5.3e-23 | 0.59 | 0.20 | 0.35 | TRUE |
| 2 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | FLT3 | 0.04 | 0.04 | lasso | 1 | 0.04 | 2.1e-05 | -9.2 | -9.2 | 4.1e-20 | 0.58 | 0.62 | 0.10 | FALSE |
| 3 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | FLT3 | 0.10 | 0.06 | lasso | 3 | 0.09 | 8.0e-06 | -9.4 | -7.8 | 6.4e-15 | 0.63 | 0.23 | 0.57 | FALSE |
| 4 | The Cancer Genome Atlas | Pancreatic Adenocarcinoma | FLT3 | 0.12 | 0.06 | blup | 96 | 0.06 | 2.4e-03 | -9.3 | -7.2 | 5.2e-13 | 0.66 | 0.09 | 0.66 | FALSE |