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chr13:49,123,516-50,962,458

Best TWAS P=2.58e-13 · Best GWAS P=1.08e-15 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	PHF11	0.06	0.00	enet	19	0.01	4.4e-02	-3.9	7.3	3.8e-13	0.05	0.02	0.67	FALSE
2	GTEx	Brain Caudate basal ganglia	EBPL	0.41	0.06	lasso	7	0.12	2.1e-04	-5.8	5.9	4.8e-09	-0.10	0.13	0.05	FALSE
3	GTEx	Brain Cerebellum	RCBTB1	0.28	0.04	enet	11	0.16	1.6e-05	3.1	-5.4	7.2e-08	0.09	0.17	0.10	TRUE
4	GTEx	Brain Cortex	EBPL	0.36	0.08	enet	24	0.14	1.5e-04	-6.0	5.8	5.0e-09	-0.14	0.20	0.05	TRUE
5	GTEx	Esophagus Gastroesophageal Junction	EBPL	0.27	0.24	enet	14	0.26	4.6e-10	-5.8	5.6	2.2e-08	-0.08	0.99	0.00	TRUE
6	GTEx	Esophagus Mucosa	EBPL	0.44	0.16	enet	35	0.24	2.6e-16	2.0	7.3	2.6e-13	-0.06	1.00	0.00	TRUE
7	GTEx	Heart Atrial Appendage	EBPL	0.17	0.04	lasso	5	0.05	2.2e-03	-6.0	5.5	4.8e-08	-0.11	0.26	0.04	FALSE
8	GTEx	Heart Left Ventricle	RCBTB1	0.16	0.13	enet	19	0.14	8.8e-08	-5.1	-5.6	1.9e-08	-0.05	0.94	0.06	TRUE
9	GTEx	Muscle Skeletal	CDADC1	0.10	0.04	enet	10	0.02	1.6e-03	-2.7	-5.5	3.4e-08	-0.01	0.81	0.01	TRUE
10	GTEx	Muscle Skeletal	PHF11	0.11	0.14	lasso	6	0.13	9.4e-13	-5.3	5.3	1.1e-07	-0.09	1.00	0.00	FALSE
11	GTEx	Pancreas	EBPL	0.18	0.10	enet	5	0.09	1.6e-04	-6.0	5.4	7.2e-08	-0.10	0.38	0.04	FALSE
12	GTEx	Skin Not Sun Exposed Suprapubic	EBPL	0.34	0.26	enet	12	0.30	4.0e-17	-5.7	5.6	2.5e-08	-0.02	1.00	0.00	FALSE
13	GTEx	Skin Not Sun Exposed Suprapubic	RCBTB1	0.17	0.03	lasso	8	0.02	1.9e-02	-7.0	6.6	5.3e-11	0.08	0.06	0.82	TRUE
14	GTEx	Skin Sun Exposed Lower leg	EBPL	0.28	0.21	lasso	5	0.20	2.5e-16	-5.6	5.6	2.2e-08	-0.11	1.00	0.00	FALSE
15	GTEx	Spleen	EBPL	0.58	0.33	enet	28	0.35	7.1e-10	0.6	5.6	1.8e-08	-0.04	0.72	0.02	FALSE
16	GTEx	Testis	EBPL	0.33	0.17	lasso	6	0.24	8.4e-11	-5.9	5.9	3.5e-09	-0.08	1.00	0.00	TRUE
17	METSIM	Adipose	PHF11	0.16	0.14	lasso	9	0.14	8.7e-20	-5.3	5.7	1.3e-08	-0.09	1.00	0.00	FALSE
18	METSIM	Adipose	SETDB2	0.06	0.03	enet	17	0.05	5.1e-08	-6.7	-5.1	3.1e-07	0.02	0.02	0.98	TRUE
19	NTR	Blood	PHF11	0.04	0.03	bslmm	406	0.04	3.1e-12	-5.6	6.2	6.8e-10	-0.06	1.00	0.00	FALSE
20	ROSMAP	Brain Pre-frontal Cortex	EBPL	0.43	0.28	lasso	8	0.43	7.3e-60	-5.8	5.8	5.6e-09	-0.06	1.00	0.00	FALSE
21	YFS	Blood	PHF11	0.16	0.16	lasso	19	0.16	5.0e-49	-5.6	5.4	5.4e-08	-0.07	1.00	0.00	FALSE
22	The Cancer Genome Atlas	Breast Invasive Carcinoma	EBPL	0.07	0.03	enet	11	0.06	2.1e-12	-5.8	5.2	1.5e-07	-0.06	0.01	0.99	FALSE
23	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	PHF11	0.13	0.13	blup	92	0.12	4.3e-06	-5.6	-5.8	8.6e-09	0.06	0.24	0.76	FALSE
24	The Cancer Genome Atlas	Lung Adenocarcinoma	EBPL	0.07	0.02	blup	59	0.03	8.9e-05	-2.2	5.3	1.3e-07	-0.14	0.01	0.92	FALSE
25	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	EBPL	0.21	0.09	enet	10	0.13	4.9e-06	-6.0	6.5	6.2e-11	-0.13	0.00	1.00	FALSE
26	The Cancer Genome Atlas	Stomach Adenocarcinoma	EBPL	0.10	0.07	enet	7	0.08	2.8e-06	-6.0	5.2	1.7e-07	-0.12	0.00	0.99	TRUE
27	The Cancer Genome Atlas	Testicular Germ Cell Tumors	RCBTB1	0.13	0.07	lasso	4	0.08	1.2e-03	-5.8	-6.7	2.6e-11	-0.08	0.01	0.93	FALSE
28	The Cancer Genome Atlas	Thyroid Carcinoma	RCBTB1	0.10	0.09	lasso	10	0.12	8.9e-12	-5.8	-6.3	3.3e-10	-0.01	0.53	0.47	TRUE