[Hub]/) : Traits : Blood White Count :

chr13:49,123,516-50,962,458

Best TWAS P=2.58e-13 · Best GWAS P=1.08e-15 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous PHF11 0.06 0.00 enet 19 0.01 4.4e-02 -3.9 7.3 3.8e-13 0.05 0.02 0.67 FALSE
2 GTEx Brain Caudate basal ganglia EBPL 0.41 0.06 lasso 7 0.12 2.1e-04 -5.8 5.9 4.8e-09 -0.10 0.13 0.05 FALSE
3 GTEx Brain Cerebellum RCBTB1 0.28 0.04 enet 11 0.16 1.6e-05 3.1 -5.4 7.2e-08 0.09 0.17 0.10 TRUE
4 GTEx Brain Cortex EBPL 0.36 0.08 enet 24 0.14 1.5e-04 -6.0 5.8 5.0e-09 -0.14 0.20 0.05 TRUE
5 GTEx Esophagus Gastroesophageal Junction EBPL 0.27 0.24 enet 14 0.26 4.6e-10 -5.8 5.6 2.2e-08 -0.08 0.99 0.00 TRUE
6 GTEx Esophagus Mucosa EBPL 0.44 0.16 enet 35 0.24 2.6e-16 2.0 7.3 2.6e-13 -0.06 1.00 0.00 TRUE
7 GTEx Heart Atrial Appendage EBPL 0.17 0.04 lasso 5 0.05 2.2e-03 -6.0 5.5 4.8e-08 -0.11 0.26 0.04 FALSE
8 GTEx Heart Left Ventricle RCBTB1 0.16 0.13 enet 19 0.14 8.8e-08 -5.1 -5.6 1.9e-08 -0.05 0.94 0.06 TRUE
9 GTEx Muscle Skeletal CDADC1 0.10 0.04 enet 10 0.02 1.6e-03 -2.7 -5.5 3.4e-08 -0.01 0.81 0.01 TRUE
10 GTEx Muscle Skeletal PHF11 0.11 0.14 lasso 6 0.13 9.4e-13 -5.3 5.3 1.1e-07 -0.09 1.00 0.00 FALSE
11 GTEx Pancreas EBPL 0.18 0.10 enet 5 0.09 1.6e-04 -6.0 5.4 7.2e-08 -0.10 0.38 0.04 FALSE
12 GTEx Skin Not Sun Exposed Suprapubic EBPL 0.34 0.26 enet 12 0.30 4.0e-17 -5.7 5.6 2.5e-08 -0.02 1.00 0.00 FALSE
13 GTEx Skin Not Sun Exposed Suprapubic RCBTB1 0.17 0.03 lasso 8 0.02 1.9e-02 -7.0 6.6 5.3e-11 0.08 0.06 0.82 TRUE
14 GTEx Skin Sun Exposed Lower leg EBPL 0.28 0.21 lasso 5 0.20 2.5e-16 -5.6 5.6 2.2e-08 -0.11 1.00 0.00 FALSE
15 GTEx Spleen EBPL 0.58 0.33 enet 28 0.35 7.1e-10 0.6 5.6 1.8e-08 -0.04 0.72 0.02 FALSE
16 GTEx Testis EBPL 0.33 0.17 lasso 6 0.24 8.4e-11 -5.9 5.9 3.5e-09 -0.08 1.00 0.00 TRUE
17 METSIM Adipose PHF11 0.16 0.14 lasso 9 0.14 8.7e-20 -5.3 5.7 1.3e-08 -0.09 1.00 0.00 FALSE
18 METSIM Adipose SETDB2 0.06 0.03 enet 17 0.05 5.1e-08 -6.7 -5.1 3.1e-07 0.02 0.02 0.98 TRUE
19 NTR Blood PHF11 0.04 0.03 bslmm 406 0.04 3.1e-12 -5.6 6.2 6.8e-10 -0.06 1.00 0.00 FALSE
20 ROSMAP Brain Pre-frontal Cortex EBPL 0.43 0.28 lasso 8 0.43 7.3e-60 -5.8 5.8 5.6e-09 -0.06 1.00 0.00 FALSE
21 YFS Blood PHF11 0.16 0.16 lasso 19 0.16 5.0e-49 -5.6 5.4 5.4e-08 -0.07 1.00 0.00 FALSE
22 The Cancer Genome Atlas Breast Invasive Carcinoma EBPL 0.07 0.03 enet 11 0.06 2.1e-12 -5.8 5.2 1.5e-07 -0.06 0.01 0.99 FALSE
23 The Cancer Genome Atlas Liver Hepatocellular Carcinoma PHF11 0.13 0.13 blup 92 0.12 4.3e-06 -5.6 -5.8 8.6e-09 0.06 0.24 0.76 FALSE
24 The Cancer Genome Atlas Lung Adenocarcinoma EBPL 0.07 0.02 blup 59 0.03 8.9e-05 -2.2 5.3 1.3e-07 -0.14 0.01 0.92 FALSE
25 The Cancer Genome Atlas Pancreatic Adenocarcinoma EBPL 0.21 0.09 enet 10 0.13 4.9e-06 -6.0 6.5 6.2e-11 -0.13 0.00 1.00 FALSE
26 The Cancer Genome Atlas Stomach Adenocarcinoma EBPL 0.10 0.07 enet 7 0.08 2.8e-06 -6.0 5.2 1.7e-07 -0.12 0.00 0.99 TRUE
27 The Cancer Genome Atlas Testicular Germ Cell Tumors RCBTB1 0.13 0.07 lasso 4 0.08 1.2e-03 -5.8 -6.7 2.6e-11 -0.08 0.01 0.93 FALSE
28 The Cancer Genome Atlas Thyroid Carcinoma RCBTB1 0.10 0.09 lasso 10 0.12 8.9e-12 -5.8 -6.3 3.3e-10 -0.01 0.53 0.47 TRUE