TWAS hub - FLT1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Colon Sigmoid	0.3890	0.1040	0.00073	0.046	NA	0.001	NA	0.047	0.0100	NA	0.3000	NA	0.0092
2	TCGA	Breast Invasive Carcinoma	0.0461	0.0192	0.00061	0.012	0.018	0.009	NA	0.009	0.0012	0.00011	0.0044	NA	0.0057

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Blood White Count	7.2	53.5	97.5	-9.9	-3.1
Average weekly beer plus cider intake	6.5	9.4	12.0	-3.5	2.6
Comparative body size at age 10	6.4	17.8	21.3	3.8	-4.6
Rheumatoid Arthritis	6.1	8.4	13.8	-3.7	-1.7
Ever depressed for a whole week	4.9	6.1	8.9	3.0	1.8
Number of incorrect matches in round	4.6	7.7	15.0	3.9	-0.6
Supplements: Calcium	4.0	4.4	6.6	-2.6	-1.5
Age at first live birth	3.7	6.5	12.6	3.6	0.6
Pack years of smoking	3.7	5.4	9.3	-3.0	-1.3
High blood pressure (mother)	3.2	4.4	4.8	-2.0	-2.2
Pain type(s) experienced in last month: Hip pain	3.2	4.0	4.4	-2.1	-1.9
Coronary Artery Disease (CAD)	3.1	3.7	4.8	-1.6	-2.2
Pack years adult smoking proportion	3.0	4.6	8.4	-2.9	-0.8
Crohns Disease (2012)	2.9	4.7	7.7	-2.8	-1.3
Age when periods started (menarche)	2.9	7.0	13.2	-0.9	3.6
Illnesses of father: Heart disease	2.8	3.8	6.4	-1.1	-2.5
Age started oral contraceptive pill	2.7	3.4	4.6	2.1	-1.5
Asthma (self-reported)	2.6	5.2	8.2	-2.9	-1.5
Father’s age at death	2.5	3.3	6.6	2.6	-0.2
Seen a psychiatrist for nerves, anxiety, tension or depression	2.5	3.2	5.4	2.3	-1.0
Mother’s age at death	2.5	3.1	5.6	2.4	0.7
Lupus	2.4	3.7	6.1	-2.5	1.1
Risk taking	2.4	3.5	4.9	-1.5	-2.2
Medication for hormone replacement therapy	2.3	2.6	2.9	-1.7	1.5
Ever unenthusiastic/disinterested for a whole week	2.3	2.8	5.4	2.3	0.4
Asthma	2.3	4.6	8.3	-2.9	-0.9
Seen doctor (GP) for nerves, anxiety, tension or depression	2.3	3.5	6.9	2.6	0.2
Bipolar Disorder (2018)	2.2	3.4	5.6	1.1	2.4
Alzheimer’s Disease (in mother)	2.2	2.6	3.8	1.2	-1.9
Diabetes (father)	2.1	2.6	4.9	2.2	0.5
Ever taken oral contraceptive pill	2.1	2.3	4.4	-0.4	2.1
Alzheimer’s Disease (including proxy)	2.0	2.9	5.3	0.7	-2.3
Illnesses of mother	2.0	2.5	2.5	1.6	1.6
Medication: Ventolin 100micrograms inhaler	2.0	2.6	3.9	-1.1	-2.0
Serious illness, injury or assault of a close relative in last 2 years	1.8	2.1	4.1	0.2	2.0
Heart disease (mother)	1.8	2.2	2.7	-1.3	-1.6
Schizophrenia vs Biploar Disorder	1.7	2.3	2.7	-1.4	-1.6
Other serious medical condition/disability diagnosed by doctor	1.7	2.2	4.0	0.6	-2.0
Vitamin and mineral supplements	1.7	2.3	4.2	2.0	0.7
Frequency of unenthusiasm / disinterest in last 2 weeks	1.7	2.3	3.6	-0.9	-1.9
Suffer from ‘nerves’	1.7	2.6	5.2	2.3	0.2
Qualifications: NVQ or HND or HNC or equivalent	1.7	2.1	3.8	-2.0	-0.6
Mineral and other dietary supplements	1.7	2.3	2.4	1.5	1.5
Systolic Blood Pressure	1.6	8.2	16.1	-4.0	0.5
Hair/balding pattern: Pattern 2	1.6	2.1	2.1	-1.4	1.4
Depression (self-reported)	1.6	1.9	3.4	1.9	-0.6
Qualifications: O levels/GCSEs or equivalent	1.6	2.6	4.7	-2.2	0.7
Mouth/teeth dental problems: Loose teeth	1.6	1.9	3.4	-0.5	-1.8
Ever had stillbirth, spontaneous miscarriage or termination	1.6	1.7	3.3	0.4	1.8
Wears glasses or contact lenses	1.6	1.9	2.0	1.3	1.4
Ever smoked	1.6	2.9	5.7	0.3	2.4
Body Mass Index (BMI) (2010)	1.5	2.0	2.1	1.4	-1.5
Lung FVC	1.5	7.7	11.6	3.4	1.9
Multivitamins +/- minerals	1.5	1.9	3.9	-2.0	-0.2
Frequency of tiredness / lethargy in last 2 weeks	1.5	2.5	4.8	-0.5	-2.2
Eye problems/disorders: None of the above	1.5	1.8	3.3	-1.8	0.4
Supplements: Fish oil (including cod liver oil)	1.5	2.0	2.8	-1.1	-1.7
Fractured/broken bones in last 5 years	1.5	1.9	2.3	1.5	1.2
Number of live births	1.4	2.0	2.4	-1.5	-1.2
Number of self-reported non-cancer illnesses	1.4	2.5	4.6	-0.6	-2.1
Medication: Paracetamol	1.4	2.2	3.0	-1.7	1.2
LDL Cholesterol	1.3	2.1	4.2	-0.2	2.0
Respiratory disease	1.3	2.8	4.0	-2.0	-1.3
Alcohol usually taken with meals	1.3	2.1	2.4	1.6	-1.3
Had other major operations	1.3	1.6	2.9	-0.6	-1.7
Mouth/teeth dental problems: Bleeding gums	1.3	1.7	2.9	1.7	0.7
Emphysema/chronic bronchitis	1.3	1.5	2.6	1.6	0.6
Pulse rate, automated reading	1.3	4.3	8.6	-2.9	-0.1
High cholesterol (Self-reported)	1.3	2.3	4.3	2.1	0.5
Medication: Gliclazide	1.2	1.3	2.6	1.6	-0.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.2	2.5	5.0	2.2	0.2
Ever had hysterectomy (womb removed)	1.1	1.3	2.2	1.5	-0.6
Impedance of leg (right)	1.1	5.1	9.3	-3.0	-1.0
Exposure to tobacco smoke at home	1.1	1.2	1.7	-1.3	0.8
Shortness of breath walking on level ground	1.1	1.3	2.6	1.6	-0.2
Average weekly red wine intake	1.1	1.7	3.2	1.8	0.3
Loneliness, isolation	1.1	1.5	2.2	-0.9	-1.5
Heart disease (siblings)	1.1	1.4	2.8	1.7	0.0
Bipolar Disorder (2011)	1.0	0.9	1.9	1.4	0.1
Past tobacco smoking	1.0	1.9	2.9	-0.9	-1.7
Had menopause	1.0	1.2	2.4	1.5	0.1
Medication: Ramipril	1.0	1.3	2.5	-1.6	0.0
Prospective memory result	1.0	1.2	1.8	-1.3	-0.8
Headache pain in last month	1.0	1.6	3.3	0.1	-1.8
Medication for pain relief, constipation, heartburn	1.0	1.7	1.9	1.4	-1.2
Number of full sisters	1.0	1.2	1.8	1.3	0.8
Illnesses of father: None of the above (group 1)	1.0	1.2	2.4	-0.2	1.5
Diastolic blood pressure, automated reading	1.0	3.1	6.1	-2.5	-0.3
Age at First Birth	0.9	1.3	2.4	1.6	-0.4
Waist Hip Ratio (WHR)	0.9	4.2	6.5	-1.4	-2.6
Supplements: Zinc	0.9	0.9	1.1	-1.1	-0.9
Waist circumference	0.9	3.3	6.2	0.6	-2.5
Falls in the last year	0.9	1.2	1.3	1.1	-1.0
Noisy workplace	0.9	1.2	2.3	-0.1	-1.5
Medication: Paracetamol	0.9	1.5	1.7	-1.3	1.2
Neck or shoulder pain in last month	0.9	1.3	2.6	1.6	-0.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.9	1.0	2.0	-1.4	-0.2
Smoking status: Previous	0.9	1.3	2.5	0.4	1.6
Long-standing illness, disability or infirmity	0.9	1.3	1.9	0.9	-1.4
Back pain experienced in last month	0.9	1.3	1.7	-0.9	-1.3
Osteoporosis (self-reported)	0.9	1.1	2.1	-1.5	0.0
Average weekly champagne plus white wine intake	0.9	1.2	1.4	1.0	-1.2
Medication: Bendroflumethiazide	0.9	1.4	1.9	-1.4	0.9
Leg fat percentage (left)	0.9	3.1	5.0	1.1	-2.2
Unable to work because of sickness or disability	0.9	1.1	1.9	0.7	-1.4
Myopia	0.9	1.3	2.4	-1.6	-0.4
Vascular/heart problems diagnosed by doctor	0.9	2.5	4.8	2.2	0.3
Alzheimer’s Disease (in father)	0.8	0.9	1.7	0.2	-1.3
Crohns Disease (2017)	0.8	1.8	3.3	-1.8	0.5
Verbal and Numeric Reasoning (VNR)	0.8	2.0	3.8	2.0	0.4
Type 2 Diabetes (T2D) (2012)	0.8	0.9	1.2	1.1	-0.8
Lung FEV1/FVC ratio	0.8	3.9	7.8	-0.1	-2.8
Eye problems/disorders: Diabetes related eye disease	0.8	0.9	1.2	-0.7	1.1
Townsend deprivation index at recruitment	0.8	1.1	1.3	-1.2	0.9
Bilateral oophorectomy (both ovaries removed)	0.8	0.9	1.8	-0.1	1.3
Hayfever, allergic rhinitis or eczema	0.8	1.8	3.1	-1.8	-0.7
Comparative height size at age 10	0.8	4.6	9.1	0.2	-3.0
Age at last live birth	0.8	1.1	1.2	1.1	-1.0
Medication for cholesterol	0.8	1.2	2.0	1.4	-0.6
Fasting Glucose	0.7	0.8	0.9	-0.8	1.0
Taking other prescription medications	0.7	1.1	1.4	-1.0	-1.2
Impedance of leg (left)	0.7	3.6	6.4	-2.5	-0.9
Hearing difficulty/problems with background noise	0.7	1.1	1.6	1.3	-0.7
Financial difficulties in last 2 years	0.7	1.0	1.6	-1.3	-0.6
Hayfever/allergic rhinitis (self-reported)	0.7	0.9	1.8	-0.1	-1.3
Medication: Ibuprofen (e.g. Nurofen)	0.7	0.9	1.3	-0.7	1.1
Length of working week for main job	0.7	0.8	1.3	-0.5	-1.1
Glaucoma (self-reported)	0.7	0.9	1.5	0.5	-1.2
Body fat percentage	0.7	2.8	5.2	0.6	-2.3
Leg fat percentage (right)	0.7	2.7	4.9	0.7	-2.2
Qualifications: College or University degree	0.7	2.3	3.2	1.8	-1.2
Alcohol intake frequency.	0.7	1.6	2.1	-1.4	1.0
Knee pain experienced in last month	0.7	1.2	2.3	1.5	-0.0
Illnesses of siblings: Diabetes	0.7	0.9	1.7	-0.2	-1.3
Depressed Affect (Nagel 2018)	0.6	1.4	2.7	0.1	-1.7
Intelligence (Savage-Jansen 2018)	0.6	1.8	3.6	1.9	0.2
Primary Biliary Cirrhosis	0.6	0.9	1.6	-0.5	-1.3
Blood Eosinophil Count	0.6	4.6	7.8	-2.8	-1.2
Allergy or Eczema	0.6	1.6	2.3	-1.5	-0.9
Ever used hormone-replacement therapy (HRT)	0.6	0.8	1.2	0.5	1.1
Trunk fat percentage	0.6	2.3	4.4	0.3	-2.1
Hip circumference	0.6	2.7	4.1	1.1	-2.0
Worrier / anxious feelings	0.6	1.2	2.0	-0.6	1.4
Mouth/teeth dental problems: Dentures	0.6	1.1	1.9	-1.4	0.5
Lung cancer (father)	0.6	0.7	1.0	1.0	-0.7
Ever highly irritable/argumentative for 2 days	0.6	0.8	1.0	-0.7	-1.0
Loud music exposure frequency	0.6	0.6	1.0	1.0	0.5
Number of full brothers	0.6	0.7	1.0	-0.6	1.0
Whole body fat mass	0.6	2.4	4.3	0.7	-2.1
Commuting to job workplace: Car/motor vehicle	0.6	0.7	1.3	-1.1	-0.4
Arm fat percentage (left)	0.6	2.5	3.6	1.1	-1.9
Friendships satisfaction	0.6	0.8	1.3	-1.1	-0.5
Arm fat mass (left)	0.6	2.4	3.3	1.2	-1.8
Cholesterol lowering medication	0.6	1.0	1.0	1.0	-1.0
Pain experienced in last month	0.6	0.9	1.4	-0.7	1.2
Impedance of whole body	0.6	2.9	5.4	-2.3	-0.7
Leg fat mass (left)	0.6	2.2	3.2	1.1	-1.8
Bipolar Disorder or Schizophrenia	0.5	1.1	1.4	1.2	0.9
Number of treatments/medications taken	0.5	0.8	1.2	-1.1	0.6
Average weekly spirits intake	0.5	0.7	1.3	0.0	1.2
Systolic blood pressure, automated reading	0.5	1.5	2.9	-1.7	0.2
Angina	0.5	0.7	0.8	0.9	0.7
Diabetes (mother)	0.5	0.6	1.2	0.2	-1.1
Tinnitus: Yes, but not now, but have in the past	0.5	0.5	1.0	1.0	-0.3
High blood pressure	0.5	1.5	2.9	-1.7	-0.3
Body mass index (BMI)	0.5	2.1	2.9	1.7	-1.2
Trunk fat mass	0.5	2.0	3.9	0.4	-2.0
Frequency of tenseness / restlessness in last 2 weeks	0.5	0.8	1.3	-0.6	-1.1
Mouth/teeth dental problems	0.5	0.8	1.2	-0.7	-1.1
Allergy	0.5	1.2	2.0	1.4	0.6
Arm fat percentage (right)	0.5	2.0	3.2	0.9	-1.8
Time employed in main current job	0.5	0.6	0.8	-0.7	-0.9
Hair/balding pattern: Pattern 3	0.5	0.8	1.1	1.0	-0.7
Pulse rate	0.5	0.8	1.6	-1.3	0.3
Medication: Amlodipine	0.5	0.7	1.2	-1.1	-0.3
High blood pressure (siblings)	0.5	0.7	1.1	-1.0	-0.6
Mean time to correctly identify matches	0.5	1.0	2.0	0.2	-1.4
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.5	0.7	1.3	-0.2	1.1
Leg fat mass (right)	0.5	1.8	2.8	0.9	-1.7
Leg pain on walking	0.5	0.7	0.7	-0.8	-0.9
Illness, injury, bereavement, stress in last 2 years	0.5	0.6	1.2	1.1	-0.1
Mood swings	0.5	0.9	1.4	-0.7	-1.2
Eye problems/disorders: Cataract	0.5	0.6	1.1	1.0	0.4
Tinnitus: Yes, now most or all of the time	0.5	0.5	0.9	0.3	1.0
Medication: Atorvastatin	0.5	0.6	1.2	1.1	0.2
Irritability	0.5	0.9	1.1	-0.8	-1.0
Irritable Bowel Disease (IBD)	0.4	0.9	1.4	-1.2	0.6
Major Depression (MDD)	0.4	0.5	0.5	0.7	0.7
Mean Putamen Volume	0.4	0.4	0.8	0.9	-0.3
Blood Platelet Count	0.4	4.1	7.6	-2.8	-0.7
BMI	0.4	2.5	4.5	2.1	-0.7
Type 2 Diabetes (T2D) (2018)	0.4	0.7	1.4	1.2	-0.2
Frequency of depressed mood in last 2 weeks	0.4	0.6	1.2	-1.1	-0.1
Relative age voice broke	0.4	0.7	1.3	0.2	1.1
Qualifications: CSEs or equivalent	0.4	0.6	0.9	-0.9	-0.5
Diverticular disease/diverticulitis (self-reported)	0.4	0.5	0.9	0.0	1.0
Alcohol intake versus 10 years previously	0.4	0.5	0.9	-0.9	0.4
Qualifications: A levels/AS levels or equivalent	0.4	1.0	1.0	1.0	0.9
Medication: Cholesterol lowering	0.4	0.6	1.1	1.1	-0.1
Medication: Lansoprazole	0.4	0.5	0.8	-0.9	-0.4
Arm fat mass (right)	0.4	1.8	2.2	1.1	-1.5
Hair/balding pattern: Pattern 4	0.4	1.0	1.4	1.2	-0.8
Birth weight of first child	0.4	0.8	1.0	-1.0	-0.7
Number of children fathered	0.4	0.5	0.6	0.8	0.5
Reason for reducing amount of alcohol drunk: Health precaution	0.4	0.5	0.9	-0.4	0.9
Pulse wave peak to peak time	0.4	0.4	0.5	-0.7	-0.6
Medication: Blood pressure	0.4	0.8	1.6	-1.3	-0.0
Angina (self-reported)	0.4	0.6	1.0	1.0	0.4
Medication: Ibuprofen	0.4	0.5	0.9	-0.1	1.0
Ever had bowel cancer screening	0.4	0.5	0.9	1.0	-0.1
Mouth/teeth dental problems: Mouth ulcers	0.4	0.6	0.8	0.9	-0.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.4	0.4	0.8	-0.1	-0.9
Breast cancer (self-reported)	0.4	0.5	0.5	0.7	0.7
Commuting to job workplace: Cycle	0.4	0.5	0.6	0.6	0.8
Heart attack/myocardial infarction (self-reported)	0.4	0.5	0.8	0.5	-0.9
Deep venous thrombosis (DVT) (self-reported)	0.4	0.5	0.9	-0.9	0.2
Neuroticism (Nagel 2018)	0.3	0.7	1.5	-0.0	-1.2
Ulcerative Colitis (UC)	0.3	0.5	0.7	-0.5	0.9
HDL Cholesterol	0.3	0.5	0.5	0.7	-0.7
Neuroticism (2016)	0.3	0.4	0.6	0.5	-0.8
Heel T-Score	0.3	2.2	4.2	2.0	-0.4
Cardiovascular Disease	0.3	1.0	2.0	-1.4	-0.3
Neuroticism	0.3	0.7	1.3	-0.1	-1.2
Hearing difficulty/problems: Yes	0.3	0.5	0.9	1.0	-0.1
Fed-up feelings	0.3	0.6	1.0	-0.4	-1.0
Stomach or abdominal pain in last month	0.3	0.3	0.6	-0.8	-0.3
Medication: Atenolol	0.3	0.4	0.6	-0.8	-0.4
Sitting height	0.3	2.1	2.5	-1.6	1.3
Heart attack	0.3	0.4	0.6	0.3	-0.8
Weight	0.3	1.6	2.1	1.1	-1.4
Impedance of arm (right)	0.3	1.2	2.4	-1.5	-0.0
Pulse wave reflection index	0.3	0.4	0.7	0.1	0.8
Blood clot in the leg (DVT)	0.3	0.4	0.8	-0.9	-0.1
Forced vital capacity (FVC), Best measure	0.3	1.0	1.9	0.0	1.4
Wheeze or whistling in the chest in last year	0.3	0.5	1.0	-1.0	0.3
Health satisfaction	0.3	0.4	0.8	0.9	-0.1
Chest pain or discomfort	0.3	0.4	0.5	0.7	-0.5
Family relationship satisfaction	0.3	0.4	0.5	-0.7	0.6
Hypertension (Self-reported)	0.3	0.9	1.8	-1.3	-0.0
Commuting to job workplace: Walk	0.3	0.4	0.4	0.5	-0.7
Osteoarthritis (self-reported)	0.3	0.3	0.7	0.1	-0.8
Hearing aid user	0.3	0.4	0.5	0.5	-0.7
Financial situation satisfaction	0.3	0.3	0.6	0.1	0.8
Commuting to job workplace: Public transport	0.3	0.4	0.8	-0.1	-0.9
Basal cell carcinoma (self-reported)	0.3	0.3	0.5	0.4	-0.7
Alcohol drinker status: Previous	0.3	0.3	0.6	0.8	-0.2
Schizophrenia (2018)	0.2	0.5	0.5	0.6	-0.7
Ovarian Cancer	0.2	0.3	0.5	-0.7	0.4
Blood Red Count	0.2	2.4	4.3	0.6	-2.1
Hand grip strength (left)	0.2	0.5	0.9	-0.3	1.0
Relative age of first facial hair	0.2	0.5	0.9	-0.9	-0.1
Medication: Co-codamol	0.2	0.2	0.4	0.7	-0.2
Severe depression (siblings)	0.2	0.3	0.5	0.7	-0.0
Hand grip strength (right)	0.2	0.7	1.0	-0.6	1.0
Average weekly fortified wine intake	0.2	0.2	0.3	0.5	0.4
Maternal smoking around birth	0.2	0.3	0.3	0.5	0.5
Supplements: Glucosamine	0.2	0.3	0.5	0.3	0.7
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.4	0.8	-0.9	0.1
Pain all over the body in last month	0.2	0.2	0.4	0.6	0.2
Neuroticism score	0.2	0.3	0.4	0.6	-0.6
Forced expiratory volume in 1-second (FEV1), Best measure	0.2	0.5	1.0	-0.1	1.0
Pulse wave Arterial Stiffness index	0.2	0.3	0.4	0.5	0.6
Impedance of arm (left)	0.2	0.9	1.7	-1.3	-0.4
Breastfed as a baby	0.2	0.2	0.3	0.5	-0.4
Tense / ‘highly strung’	0.2	0.3	0.4	0.6	-0.3
Peak expiratory flow (PEF)	0.2	0.4	0.7	-0.3	-0.9
Gout (self-reported)	0.2	0.3	0.4	-0.4	-0.7
Exposure to tobacco smoke outside home	0.2	0.3	0.6	0.1	-0.8
Medication: Allopurinol	0.2	0.3	0.4	-0.5	-0.6
Medication: Seretide 50 evohaler	0.2	0.3	0.6	-0.8	0.0
Had major operations	0.2	0.2	0.3	0.5	-0.4
Medication: Aspirin	0.2	0.3	0.6	-0.8	-0.0
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.4	0.7	-0.8	0.4
Diabetes diagnosed by doctor	0.2	0.3	0.6	0.8	-0.1
Qualifications: nursing, teaching	0.2	0.3	0.4	-0.7	0.5
Medication: Aspirin	0.2	0.2	0.3	-0.6	0.3
Guilty feelings	0.2	0.3	0.5	0.4	-0.7
Eye problems/disorders: Glaucoma	0.2	0.2	0.3	0.4	-0.5
Medication: Blood pressure	0.2	0.3	0.6	-0.8	0.1
Medication: Lisinopril	0.2	0.2	0.3	-0.3	0.6
Alcohol drinker status: Never	0.2	0.3	0.3	-0.6	-0.5
Depression (Nagel 2018)	0.1	0.2	0.3	0.2	-0.5
Reaction Time	0.1	0.2	0.5	-0.1	-0.7
Breast Cancer	0.1	0.1	0.3	0.1	0.5
Prostate Cancer	0.1	0.2	0.3	-0.5	0.4
HbA1C	0.1	0.1	0.2	0.4	0.1
Triglycerides	0.1	0.2	0.3	0.1	-0.6
Smoking Status	0.1	0.1	0.2	0.5	0.2
Hypothyroidism (self reported)	0.1	0.1	0.2	-0.5	-0.2
Chronotype (morning person)	0.1	0.2	0.4	0.6	-0.2
Sensitivity / hurt feelings	0.1	0.2	0.3	0.0	-0.6
Medication: Metformin	0.1	0.1	0.2	0.4	0.2
Leg fat-free mass (left)	0.1	0.5	0.8	0.9	-0.5
Current tobacco smoking	0.1	0.1	0.2	0.4	0.2
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.3	0.3	0.5	-0.5
Serious illness, injury or assault to yourself	0.1	0.2	0.3	-0.2	0.5
Chronic bronchitis/emphysema (father)	0.1	0.1	0.2	-0.5	-0.3
Leg predicted mass (left)	0.1	0.6	0.7	0.8	-0.7
Nervous feelings	0.1	0.3	0.3	-0.4	0.6
Forced vital capacity (FVC)	0.1	0.4	0.8	0.0	0.9
Medication: Simvastatin	0.1	0.2	0.3	0.3	-0.6
Fluid intelligence score	0.1	0.3	0.3	0.6	-0.4
Illnesses of siblings	0.1	0.1	0.1	0.3	0.2
Trunk predicted mass	0.1	0.3	0.3	0.5	-0.6
Standing height	0.1	1.0	1.6	-1.2	-0.7
Arm fat-free mass (right)	0.1	0.5	0.6	0.7	-0.8
Worry too long after embarrassment	0.1	0.1	0.1	0.3	-0.3
Migraine (self-reported)	0.1	0.1	0.2	-0.5	0.0
Medication: Omeprazole	0.1	0.1	0.3	-0.2	0.5
Arm predicted mass (right)	0.1	0.7	0.8	0.9	-0.8
Supplements: Vitamin C	0.1	0.1	0.2	-0.5	0.1
Whole body fat-free mass	0.1	0.4	0.6	0.8	-0.5
Leg fat-free mass (right)	0.1	0.8	1.4	1.2	-0.3
Whole body water mass	0.1	0.6	0.7	0.8	-0.7
Leg predicted mass (right)	0.1	0.7	1.3	1.2	-0.4
Miserableness	0.1	0.2	0.4	0.0	-0.6
Illnesses of father: High blood pressure	0.1	0.1	0.2	0.3	-0.4
Basal metabolic rate	0.1	0.6	0.7	0.7	-0.8
Arm fat-free mass (left)	0.1	0.5	0.6	0.7	-0.8
Number of operations (self-reported)	0.1	0.1	0.1	0.4	-0.3
Ever had prostate specific antigen (PSA) test	0.1	0.1	0.3	0.0	-0.5
Medication: Omeprazole (e.g. Zanprol)	0.1	0.2	0.2	0.3	0.5
Arm predicted mass (left)	0.1	0.6	0.9	0.6	-0.9
Worry (Nagel 2018)	0.0	0.0	0.0	0.1	-0.0
Schizophrenia (2014)	0.0	0.1	0.2	0.2	-0.4
Ulcerative Colitis	0.0	0.1	0.1	-0.2	-0.3
Height	0.0	0.6	1.0	-0.4	-1.0
Hair Pigment	0.0	0.5	0.9	-0.9	0.3
Tanning	0.0	0.3	0.5	-0.4	0.7
Medication: Levothyroxine sodium	0.0	0.0	0.1	-0.1	0.3
Qualifications: None of the above	0.0	0.1	0.2	-0.4	0.0
Diabetes (self-reported)	0.0	0.1	0.1	0.3	-0.1
Trunk fat-free mass	0.0	0.3	0.3	0.5	-0.6
Forced expiratory volume in 1-second (FEV1)	0.0	0.1	0.3	0.0	0.5
Happiness	0.0	0.0	0.0	-0.2	-0.0
Medication for cholesterol, blood pressure or diabetes	0.0	0.0	0.0	-0.1	-0.2
Hypothyroidism/myxoedema (self-reported)	0.0	0.0	0.0	0.1	-0.1
Birth weight	0.0	0.0	0.0	0.1	-0.1
Chronic bronchitis/emphysema (mother)	0.0	0.0	0.0	-0.1	-0.2
Overall health rating	0.0	0.1	0.1	0.3	-0.1
Handedness (chirality/laterality): Left-handed	0.0	0.1	0.1	-0.1	0.3
Smoking status: Current	0.0	0.1	0.1	0.3	-0.2

Hub : Genes

FLT1

Models

Trait associations