Best TWAS P=1.52e-10 · Best GWAS P=1.54e-11 conditioned to 0.00171
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Testis | RNF2 | 0.09 | 0.05 | lasso | 5 | 0.01 | 0.07140 | -6.5 | 5.5 | 4.1e-08 | -0.86 | 0.03 | 0.92 | FALSE |
| 2 | GTEx | Uterus | EDEM3 | 0.27 | 0.02 | enet | 20 | 0.13 | 0.00163 | -6.1 | -6.4 | 1.5e-10 | 0.71 | 0.06 | 0.56 | TRUE |
| 3 | The Cancer Genome Atlas | Colon Adenocarcinoma | C1orf26 | 0.07 | 0.02 | blup | 71 | 0.05 | 0.00101 | -5.0 | -6.3 | 3.3e-10 | 0.69 | 0.06 | 0.70 | FALSE |
| 4 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | C1orf26 | 0.02 | 0.01 | blup | 71 | 0.02 | 0.00159 | -4.6 | -5.8 | 8.0e-09 | 0.77 | 0.08 | 0.68 | FALSE |
| 5 | The Cancer Genome Atlas | Brain Lower Grade Glioma | C1orf26 | 0.03 | 0.01 | blup | 71 | 0.02 | 0.00085 | -4.7 | -6.0 | 1.4e-09 | 0.70 | 0.05 | 0.62 | FALSE |
| 6 | The Cancer Genome Atlas | Stomach Adenocarcinoma | RNF2 | 0.08 | 0.00 | enet | 7 | 0.02 | 0.00708 | -6.7 | 5.7 | 1.2e-08 | -0.67 | 0.01 | 0.80 | FALSE |