TWAS
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Usage
Models
Genes
Traits
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Traits
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Blood White Count
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chr1:180,186,713-181,614,143
Best TWAS P=2.63e-09 · Best GWAS P=1.16e-09 conditioned to 1
180.2M
180.4M
180.6M
180.8M
181M
181.2M
181.4M
181.6M
0
2
4
6
8
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
CommonMind
Brain Pre-frontal Cortex
KIAA1614
0.19
0.17
lasso
7
0.18
2.9e-21
-6.1
6.0
2.6e-09
-0.97
0.00
1.00
TRUE
3
The Cancer Genome Atlas
Thyroid Carcinoma
KIAA1614
0.25
0.08
lasso
3
0.07
3.6e-07
-6.1
5.4
5.5e-08
-0.94
0.00
1.00
FALSE
2
The Cancer Genome Atlas
Brain Lower Grade Glioma
KIAA1614
0.14
0.05
enet
11
0.07
9.9e-09
4.6
5.2
1.8e-07
-0.54
0.04
0.93
FALSE