Hub : Genes

RNF2

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Artery Aorta 0.1930 0.0710 0.0015 -0.005 NA 0.016 NA 0.000 8.2e-01 NA 4.2e-02 NA 3.1e-01
2 GTEx Colon Transverse 0.1240 0.0520 0.0049 0.023 NA -0.005 NA 0.005 2.7e-02 NA 7.2e-01 NA 1.8e-01
3 GTEx Testis 0.0910 0.0450 0.0062 0.048 NA 0.006 NA 0.015 3.6e-03 NA 1.7e-01 NA 7.1e-02
4 GTEx Thyroid 0.0810 0.0350 0.0039 -0.001 NA -0.002 NA -0.002 3.9e-01 NA 4.7e-01 NA 5.6e-01
5 NTR Blood 0.0902 0.0172 0.0000 0.089 0.103 0.104 0.106 0.105 2.9e-27 2.0e-31 1.0e-31 3.4e-32 4.0e-32
6 TCGA Ovarian Serous Cystadenocarcinoma 0.0760 0.0490 0.0016 0.044 0.037 0.026 NA 0.040 6.0e-04 1.6e-03 7.3e-03 NA 9.9e-04
7 TCGA Prostate Adenocarcinoma 0.0357 0.0232 0.0037 0.006 0.015 0.007 NA 0.010 7.2e-02 1.0e-02 5.2e-02 NA 3.0e-02
8 TCGA Stomach Adenocarcinoma 0.0770 0.0610 0.0028 -0.002 0.015 0.024 NA 0.022 5.1e-01 2.8e-02 7.1e-03 NA 9.0e-03

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bipolar Disorder (2018) 0.3 0.5 1.9 -0.0 1.4 0.1 0.0 1.1 -0.1 -0.6 -0.5
Bipolar Disorder or Schizophrenia 1.0 2.5 6.7 -1.7 0.7 -1.0 0.0 2.6 -1.8 -2.4 -0.8
Depressed Affect (Nagel 2018) 1.4 2.8 7.8 1.9 -0.8 2.8 0.0 0.5 2.4 1.3 1.6
Depression (Nagel 2018) 0.8 1.2 2.8 1.5 -0.4 1.7 0.0 0.5 1.7 0.8 0.7
Intelligence (Savage-Jansen 2018) 2.4 7.5 14.1 -3.8 2.4 -2.7 0.0 2.8 -3.4 -3.6 -0.5
Neuroticism (Nagel 2018) 0.1 0.3 0.9 0.9 -0.0 0.9 0.0 0.9 0.3 -0.1 0.3
Schizophrenia (2018) 1.5 3.0 6.5 -2.1 -0.1 -1.4 0.0 2.5 -2.2 -2.5 -0.6
Schizophrenia vs Biploar Disorder 0.3 0.4 1.0 -1.0 -0.5 -1.0 0.0 -0.2 -0.8 -0.4 -0.1
Worry (Nagel 2018) 0.3 0.6 1.3 -0.0 0.5 -1.1 0.0 0.3 -1.0 -1.1 -1.0
Alzheimer’s Disease (in mother) 0.6 0.7 2.5 -0.3 1.6 -0.6 0.0 -0.4 -0.6 0.0 -1.5
Alzheimer’s Disease (in father) 0.1 0.2 0.7 0.0 0.2 0.5 0.0 0.3 0.4 0.1 0.8
Alzheimer’s Disease (including proxy) 0.4 0.6 3.3 0.4 1.8 0.4 0.0 -0.4 0.7 0.6 -0.3
Crohns Disease (2017) 1.9 4.1 9.7 3.1 0.5 2.1 0.0 -1.8 2.6 3.0 0.0
Irritable Bowel Disease (IBD) 1.9 4.5 9.1 2.7 -0.6 3.0 0.0 -0.9 3.0 2.8 1.5
Ulcerative Colitis (UC) 0.9 1.8 3.8 1.2 -1.6 2.0 0.0 0.1 1.4 1.2 1.6
Major Depression (MDD) 0.2 0.2 0.7 0.4 -0.8 0.7 0.0 0.1 0.4 0.2 -0.2
Reaction Time 0.1 0.1 0.4 -0.2 -0.5 0.4 0.0 0.1 0.6 0.3 0.2
Verbal and Numeric Reasoning (VNR) 0.9 2.2 4.8 -2.0 1.6 -0.9 0.0 2.2 -1.5 -1.7 -0.4
Breast Cancer 0.2 0.4 1.2 -0.6 -1.1 -0.8 0.0 -0.6 -0.3 0.1 -0.6
Ovarian Cancer 1.3 1.7 7.0 -0.2 1.4 -1.4 0.0 -0.4 -1.2 -0.9 -2.7
Prostate Cancer 0.5 0.7 2.5 -1.6 0.1 0.5 0.0 1.2 -0.6 -1.0 0.1
Age at First Birth 0.1 0.1 0.7 -0.3 -0.4 0.2 0.0 -0.1 0.1 0.2 0.8
Bipolar Disorder (2011) 1.2 1.2 2.3 -0.9 1.5 -0.9 0.0 1.2 -1.4 -1.4 -0.3
Body Mass Index (BMI) (2010) 0.2 0.2 0.9 -0.1 -1.0 0.5 0.0 0.8 0.0 -0.3 -0.3
Coronary Artery Disease (CAD) 0.5 0.6 1.8 -0.4 -1.4 -0.8 0.0 0.8 -0.8 -0.7 -0.2
Crohns Disease (2012) 1.5 2.5 6.3 2.5 1.1 0.5 0.0 -1.9 1.0 2.1 -1.6
Mean Putamen Volume 0.1 0.1 0.5 -0.2 -0.7 0.0 0.0 -0.2 0.1 0.2 0.4
Fasting Glucose 0.8 1.0 1.9 1.4 0.4 1.4 0.0 -0.7 1.4 1.2 0.3
HbA1C 0.4 0.4 1.1 0.2 -0.5 0.5 0.0 -1.1 0.7 1.0 -0.4
HDL Cholesterol 0.2 0.3 1.0 -1.0 0.7 0.2 0.0 0.6 -0.1 -0.3 0.3
LDL Cholesterol 0.4 0.7 3.2 0.6 1.8 0.1 0.0 -1.0 0.4 0.4 -0.7
Lupus 0.8 1.3 4.9 -0.9 -2.2 -1.5 0.0 -0.2 -1.2 -0.5 -0.6
Neuroticism (2016) 1.4 2.0 5.2 -1.0 0.8 -1.9 0.0 0.7 -2.3 -1.9 -1.3
Primary Biliary Cirrhosis 0.5 0.7 1.6 -0.9 0.2 -0.8 0.0 1.2 -1.1 -1.2 0.2
Rheumatoid Arthritis 0.4 0.5 1.7 0.1 1.3 -0.7 0.0 0.1 -0.7 -0.5 -1.1
Schizophrenia (2014) 1.4 3.1 7.1 -1.8 -0.2 -1.6 0.0 2.5 -2.3 -2.7 -0.6
Triglycerides 0.2 0.3 2.1 0.5 -1.4 0.2 0.0 0.2 0.1 -0.1 0.3
Type 2 Diabetes (T2D) (2012) 1.0 1.1 3.3 0.1 -0.3 1.6 0.0 1.8 0.5 -0.6 1.5
Ulcerative Colitis 0.5 0.7 1.5 0.9 -1.2 1.2 0.0 0.4 0.7 0.5 1.1
Blood Eosinophil Count 0.9 6.9 22.7 -2.5 -0.5 -0.9 0.0 4.8 -1.9 -4.0 2.3
Blood Platelet Count 1.9 22.3 54.9 1.4 -4.2 7.1 0.0 3.4 6.2 1.8 7.4
Blood Red Count 0.3 2.8 7.0 0.7 2.5 2.6 0.0 0.4 2.2 1.5 1.3
Blood White Count 1.7 12.7 32.5 -0.4 -2.0 5.5 0.0 4.0 4.3 0.4 5.7
Heel T-Score 0.8 6.3 12.3 -2.5 -1.8 -3.5 0.0 1.3 -3.5 -2.5 -2.8
BMI 1.3 7.8 23.7 2.2 -0.6 4.9 0.0 0.8 4.3 2.2 3.0
Height 0.3 6.2 16.0 1.0 2.1 -2.8 0.0 -4.0 -1.2 2.0 -3.8
Waist Hip Ratio (WHR) 1.0 4.7 16.3 -0.9 -0.1 2.6 0.0 3.2 1.7 -0.7 4.0
Systolic Blood Pressure 0.6 3.0 8.0 -2.4 -1.9 1.3 0.0 1.9 0.3 -1.0 2.8
Smoking Status 0.2 0.4 1.3 0.2 -0.3 0.2 0.0 -1.0 0.5 1.1 0.8
Allergy or Eczema 1.0 2.6 7.9 -0.1 -0.6 -2.8 0.0 -0.6 -2.2 -0.7 -2.6
Cardiovascular Disease 0.9 2.8 8.1 -0.0 0.1 2.8 0.0 1.2 2.2 0.6 2.9
Hypothyroidism (self reported) 0.5 1.1 4.0 -0.9 0.5 -1.5 0.0 -0.4 -1.3 0.1 -2.0
Respiratory disease 0.3 0.7 1.2 -0.6 -0.0 -1.0 0.0 1.0 -1.1 -1.0 -1.1
Type 2 Diabetes (T2D) (2018) 0.4 0.7 2.2 -0.9 0.4 1.5 0.0 0.4 1.0 0.4 1.1
Lung FEV1/FVC ratio 0.1 0.6 2.9 -1.4 1.7 -0.1 0.0 -0.0 -0.0 -0.2 0.1
Lung FVC 0.7 3.7 10.1 1.1 0.3 -3.1 0.0 -2.3 -1.9 0.1 -3.2
Neuroticism 0.2 0.4 2.0 1.4 -0.1 0.8 0.0 0.2 0.8 0.2 0.5
Chronotype (morning person) 1.3 3.1 7.1 -2.5 -0.6 -2.3 0.0 0.9 -2.7 -2.1 -0.8
Hair Pigment 0.1 1.9 6.2 0.6 -0.6 2.5 0.0 -0.3 2.5 1.4 0.3
Tanning 0.1 1.1 4.7 -0.0 -0.3 0.3 0.0 1.7 -0.2 -1.0 2.2
Hand grip strength (left) 3.2 8.5 25.4 -0.2 1.5 -4.3 0.0 -2.9 -3.6 -0.6 -5.0
Number of treatments/medications taken 0.2 0.4 1.2 0.3 -0.6 1.1 0.0 0.5 0.7 0.3 1.0
Average weekly spirits intake 1.5 1.8 6.6 -0.5 1.7 1.1 0.0 1.5 1.0 -0.8 2.6
Sensitivity / hurt feelings 0.5 0.9 2.8 -0.7 -0.7 -0.3 0.0 1.7 -0.7 -1.7 0.4
Frequency of depressed mood in last 2 weeks 1.2 1.7 4.2 1.6 0.1 2.0 0.0 -0.1 2.0 1.3 0.9
Hearing difficulty/problems: Yes 0.6 0.9 2.4 -0.2 -0.8 -1.6 0.0 0.2 -1.5 -1.0 -1.0
Relative age of first facial hair 0.5 1.0 3.6 -0.9 1.9 1.0 0.0 1.0 1.0 -0.3 0.9
Other serious medical condition/disability diagnosed by doctor 1.0 1.3 4.0 1.8 -0.3 -0.9 0.0 -2.0 -0.4 1.1 -1.1
Ever used hormone-replacement therapy (HRT) 0.3 0.4 0.7 0.3 -0.8 0.8 0.0 -0.5 0.8 0.7 -0.4
Ever had hysterectomy (womb removed) 0.4 0.4 2.2 -0.3 -1.5 0.4 0.0 -0.2 0.6 0.6 0.4
Systolic blood pressure, automated reading 0.5 1.4 3.2 -0.2 -1.8 1.8 0.0 0.2 1.1 0.6 1.7
Eye problems/disorders: Diabetes related eye disease 0.7 0.7 3.4 -0.2 1.8 0.3 0.0 -0.8 0.2 0.2 -1.2
Angina 1.3 1.7 3.8 0.2 -1.5 1.7 0.0 1.7 1.3 -0.3 2.0
Medication for hormone replacement therapy 1.0 1.1 3.9 0.7 -2.0 -0.8 0.0 -1.1 -0.3 0.5 -1.5
Vitamin and mineral supplements 0.1 0.2 0.5 -0.6 0.3 0.7 0.0 0.7 0.4 0.1 -0.2
Supplements: Zinc 0.3 0.4 1.2 -0.5 -0.3 -0.5 0.0 1.1 -0.8 -0.8 0.2
Medication: Co-codamol 1.2 1.4 4.0 2.0 0.9 1.4 0.0 -0.5 1.3 1.1 1.2
Medication: Metformin 1.3 1.8 4.1 0.4 -0.9 2.0 0.0 -0.5 2.0 1.6 1.6
Diabetes (father) 1.3 1.6 3.6 -1.9 -0.3 -1.3 0.0 1.1 -1.7 -1.7 -0.6
Diabetes (mother) 0.3 0.4 1.5 0.5 -0.2 -0.7 0.0 -0.4 -1.0 -0.2 -1.2
Severe depression (siblings) 0.1 0.1 0.4 -0.4 0.3 -0.0 0.0 0.4 0.3 -0.6 0.3
Pack years adult smoking proportion 0.3 0.4 1.0 0.7 -0.9 0.4 0.0 0.4 0.6 0.4 1.0
Impedance of leg (right) 0.2 0.8 2.8 -0.2 -1.7 -0.5 0.0 0.8 -0.9 -1.2 0.3
Leg fat-free mass (left) 0.2 1.3 3.0 1.0 1.7 0.6 0.0 -1.4 1.0 1.6 -0.9
Trunk fat percentage 1.1 4.4 10.8 2.1 -1.7 3.3 0.0 0.7 2.9 1.6 2.4
Hand grip strength (right) 1.7 4.8 16.3 0.0 1.5 -2.9 0.0 -2.1 -2.5 -0.4 -4.0
Townsend deprivation index at recruitment 1.0 1.4 5.0 -0.5 0.7 1.8 0.0 0.9 1.2 -0.1 2.2
Current tobacco smoking 1.0 1.6 3.3 1.2 -0.6 1.2 0.0 -1.3 1.4 1.7 1.8
Average weekly fortified wine intake 1.2 1.4 3.5 -1.9 -1.0 -1.0 0.0 1.5 -1.3 -1.3 -0.0
Maternal smoking around birth 0.3 0.5 2.0 0.7 -1.4 -0.4 0.0 -0.9 -0.1 0.3 -0.6
Fed-up feelings 2.8 5.1 14.7 1.8 1.0 3.8 0.0 0.9 3.5 1.3 2.8
Frequency of unenthusiasm / disinterest in last 2 weeks 2.9 3.9 8.1 2.9 -0.0 2.7 0.0 -1.0 2.8 2.4 0.8
Relative age voice broke 0.5 0.8 2.5 0.0 1.6 1.1 0.0 0.7 0.8 -0.7 0.9
Taking other prescription medications 0.6 0.9 1.8 1.3 -0.7 0.3 0.0 -1.2 0.5 1.3 -1.2
Age when periods started (menarche) 0.1 0.2 0.6 -0.5 0.8 -0.4 0.0 -0.1 0.1 -0.3 0.4
Bilateral oophorectomy (both ovaries removed) 0.8 0.9 3.2 -0.6 -1.8 0.8 0.0 0.1 0.5 0.6 1.4
Heel bone mineral density (BMD) T-score, automated (left) 0.1 0.2 0.7 0.2 -0.9 0.3 0.0 -0.4 0.8 0.4 0.1
Tinnitus: Yes, but not now, but have in the past 1.5 1.6 4.2 -1.5 -1.0 0.1 0.0 2.0 -1.1 -1.9 0.8
Qualifications: CSEs or equivalent 0.5 0.7 2.8 0.1 -0.9 1.0 0.0 0.1 1.0 0.4 1.7
Serious illness, injury or assault to yourself 0.5 0.6 3.7 -0.3 -1.9 -0.1 0.0 0.8 -0.1 -0.2 0.8
High blood pressure 0.7 1.9 6.7 0.4 0.0 2.2 0.0 1.3 1.5 -0.1 2.6
Hayfever, allergic rhinitis or eczema 0.6 1.4 4.6 0.1 -0.3 -2.1 0.0 -0.8 -1.3 -0.3 -1.9
Multivitamins +/- minerals 0.3 0.3 1.1 -0.1 -0.1 -0.7 0.0 0.2 -0.9 -1.0 0.5
Stomach or abdominal pain in last month 2.1 2.6 4.5 1.0 -2.0 2.1 0.0 -0.4 2.0 1.7 2.1
Supplements: Glucosamine 0.6 0.8 3.1 0.7 0.7 -1.3 0.0 -0.4 -0.9 0.1 -1.8
Diverticular disease/diverticulitis (self-reported) 0.4 0.4 1.2 0.5 1.1 0.1 0.0 -0.8 0.3 0.5 -1.0
Medication: Atenolol 0.6 0.7 2.1 -0.0 0.9 1.3 0.0 1.4 0.5 -0.3 0.9
Medication: Levothyroxine sodium 0.2 0.4 1.2 0.1 0.6 -0.4 0.0 -0.7 -0.0 0.8 -1.1
Sitting height 0.4 3.1 9.2 -1.1 1.4 -2.2 0.0 -2.1 -1.6 0.6 -3.0
Chronic bronchitis/emphysema (father) 0.3 0.3 0.9 0.3 -0.4 0.5 0.0 -1.0 0.4 0.6 -0.9
High blood pressure (mother) 0.2 0.3 0.9 -0.9 -0.1 -0.1 0.0 0.8 -0.5 -1.0 0.4
Body mass index (BMI) 1.2 5.1 14.0 2.2 -1.2 3.7 0.0 0.3 3.4 2.1 2.1
Impedance of leg (left) 0.2 1.0 4.1 -0.4 -2.0 -0.3 0.0 1.2 -0.7 -1.2 0.8
Leg predicted mass (left) 0.2 1.3 2.7 1.0 1.6 0.5 0.0 -1.4 0.9 1.5 -1.1
Trunk fat mass 1.0 4.2 9.8 2.4 -1.0 3.1 0.0 -0.1 3.0 2.2 1.7
Waist circumference 1.3 4.8 14.0 1.3 -0.2 3.7 0.0 1.2 3.3 1.6 2.7
Number of incorrect matches in round 0.5 0.8 2.9 0.2 0.2 -0.1 0.0 -1.7 -0.1 0.8 -1.7
Past tobacco smoking 0.1 0.2 0.6 -0.2 -0.2 0.5 0.0 0.7 0.4 -0.1 0.8
Alcohol usually taken with meals 0.9 1.4 4.0 -2.0 -0.8 -1.1 0.0 1.0 -1.1 -1.2 1.3
Nervous feelings 0.9 1.7 3.9 -0.7 1.0 -1.9 0.0 0.1 -2.0 -1.4 -1.6
Frequency of tenseness / restlessness in last 2 weeks 1.3 1.9 4.3 1.9 0.8 1.7 0.0 -0.8 2.1 1.7 0.7
Hearing difficulty/problems with background noise 1.2 1.9 5.9 -0.5 -0.1 -2.4 0.0 -0.6 -1.8 -1.1 -2.0
Hair/balding pattern: Pattern 2 0.2 0.3 0.8 0.9 -0.7 -0.3 0.0 -0.3 0.1 0.7 -0.0
Had menopause 0.4 0.5 1.1 0.9 0.7 0.6 0.0 -1.0 0.9 1.0 -0.0
Had other major operations 0.1 0.1 0.4 -0.5 -0.6 0.3 0.0 0.3 0.6 -0.2 0.2
Forced vital capacity (FVC) 0.8 3.2 8.9 -1.1 2.0 -3.0 0.0 -0.7 -2.3 -1.2 -2.1
Heel bone mineral density (BMD) T-score, automated (right) 0.1 0.1 0.7 -0.2 -0.8 0.1 0.0 -0.2 0.3 0.1 -0.4
Ever unenthusiastic/disinterested for a whole week 0.4 0.5 1.3 0.9 -1.1 0.6 0.0 -0.8 0.8 0.7 0.3
Qualifications: None of the above 0.6 1.4 3.0 1.5 -0.1 1.7 0.0 -1.0 1.6 1.4 0.3
Financial difficulties in last 2 years 0.3 0.4 1.0 0.4 0.7 0.6 0.0 -0.6 1.0 0.3 0.9
Mouth/teeth dental problems 0.4 0.6 2.1 -0.1 1.5 0.0 0.0 -1.2 0.4 0.9 -0.8
Heart attack 0.7 0.9 2.2 0.5 -1.2 1.5 0.0 0.8 1.1 0.4 1.3
Allergy 0.5 1.2 3.6 -0.5 0.2 1.9 0.0 0.4 1.3 0.6 1.8
Pain all over the body in last month 0.7 0.8 3.3 0.8 -1.8 0.9 0.0 0.2 0.7 0.5 0.8
Diabetes (self-reported) 0.9 1.4 4.4 0.1 0.6 2.1 0.0 -0.0 1.5 1.1 1.6
Hayfever/allergic rhinitis (self-reported) 1.6 2.1 5.3 1.3 -1.8 -1.6 0.0 -2.3 -0.7 1.1 -1.4
Medication: Ramipril 0.7 0.9 2.2 0.2 -1.5 1.4 0.0 0.5 1.2 0.3 1.0
Medication: Simvastatin 0.9 1.4 5.1 -0.0 0.3 1.9 0.0 0.7 1.4 0.2 2.2
Fluid intelligence score 0.8 1.6 3.2 -1.8 1.4 -1.4 0.0 1.3 -1.4 -1.1 -0.9
Illnesses of siblings 1.0 1.4 4.6 1.3 -0.4 0.3 0.0 -2.1 0.9 1.9 -0.2
Neuroticism score 0.1 0.2 0.5 0.6 0.5 0.5 0.0 0.7 0.3 -0.5 0.5
Weight 0.6 2.7 6.3 2.0 0.3 2.3 0.0 -0.9 2.5 2.3 0.3
Impedance of arm (right) 0.3 1.4 3.5 -0.6 -0.9 -1.9 0.0 0.7 -1.8 -1.6 -0.4
Arm fat percentage (right) 1.0 3.8 9.4 2.0 -1.4 3.1 0.0 0.5 2.9 1.6 1.9
Trunk fat-free mass 0.4 2.5 5.7 0.9 2.3 -0.4 0.0 -2.2 0.4 1.7 -2.4
Hip circumference 0.6 2.6 6.7 1.8 -0.3 2.4 0.0 -0.3 2.6 2.1 0.6
Time employed in main current job 0.1 0.1 0.1 0.3 0.4 -0.0 0.0 -0.4 -0.2 0.0 0.4
Alcohol intake versus 10 years previously 0.8 1.1 4.4 -0.6 -2.1 -0.0 0.0 0.6 0.1 -0.3 1.9
Father’s age at death 1.6 2.2 6.0 -1.1 1.2 -2.0 0.0 -1.1 -1.9 -0.5 -2.4
Worrier / anxious feelings 0.3 0.5 1.1 1.0 0.9 -0.9 0.0 -0.6 -0.4 -0.1 -0.7
Frequency of tiredness / lethargy in last 2 weeks 3.2 5.2 12.7 2.7 0.7 3.1 0.0 -0.9 3.6 2.5 2.2
Falls in the last year 0.2 0.3 1.5 0.3 -1.2 -0.9 0.0 -0.0 -0.5 -0.0 -0.1
Hair/balding pattern: Pattern 3 0.3 0.5 1.4 -0.4 -0.7 0.7 0.0 -0.4 1.0 0.5 1.2
Number of live births 0.5 0.7 3.1 0.2 1.8 0.8 0.0 -0.3 0.6 0.9 -0.4
Forced expiratory volume in 1-second (FEV1) 0.7 2.2 6.4 -1.1 1.5 -2.5 0.0 -0.6 -1.9 -1.1 -1.6
Pulse rate 0.1 0.1 0.6 -0.1 -0.5 0.5 0.0 0.1 0.7 0.1 0.3
Happiness 1.6 1.9 4.2 2.0 -0.3 2.0 0.0 -1.1 1.8 1.7 -0.0
Noisy workplace 1.1 1.3 7.8 0.1 -2.8 -0.2 0.0 1.0 -0.3 -1.0 0.7
Qualifications: A levels/AS levels or equivalent 0.4 0.8 2.2 -0.8 -0.5 -1.5 0.0 -0.4 -0.9 -0.0 -1.5
Serious illness, injury or assault of a close relative in last 2 years 0.6 0.7 1.7 -0.7 0.6 -1.0 0.0 0.9 -1.3 -1.2 -0.4
Mouth/teeth dental problems: Dentures 1.1 1.9 5.9 -0.7 -2.4 -0.4 0.0 1.9 -0.8 -1.5 1.6
Asthma 0.3 0.6 2.1 0.4 0.1 -1.1 0.0 -0.0 -1.0 -0.6 -1.4
Medication: Ibuprofen (e.g. Nurofen) 0.2 0.2 1.0 0.3 -0.5 -0.2 0.0 0.3 -0.5 -0.2 1.0
Medication: Cholesterol lowering 0.4 0.6 1.4 0.6 -0.2 1.1 0.0 0.0 1.1 0.6 1.2
Depression (self-reported) 0.4 0.5 1.6 0.9 1.2 0.1 0.0 -0.8 -0.0 0.3 -0.7
Medication: Lansoprazole 0.8 0.9 2.7 0.9 -0.5 1.6 0.0 0.6 1.4 0.1 1.2
Prospective memory result 0.3 0.4 1.1 0.6 -1.1 -0.6 0.0 0.2 -0.9 -0.6 -0.0
Lung cancer (father) 2.8 3.3 10.2 1.5 -0.0 3.2 0.0 0.1 2.8 1.8 1.7
Illnesses of mother 0.2 0.2 0.6 0.4 0.4 -0.4 0.0 -0.5 0.4 0.6 0.8
Forced expiratory volume in 1-second (FEV1), Best measure 0.8 2.4 7.8 -0.2 1.0 -2.8 0.0 -1.0 -2.0 -0.8 -2.2
Pulse wave Arterial Stiffness index 0.4 0.5 3.0 -0.0 -1.7 0.4 0.0 -0.4 0.6 0.7 -0.2
Impedance of arm (left) 0.2 0.9 2.1 -0.2 -1.5 -1.2 0.0 0.8 -1.1 -1.1 0.4
Arm fat mass (right) 0.9 3.5 8.7 2.0 -0.9 3.0 0.0 0.0 2.9 1.9 1.6
Trunk predicted mass 0.4 2.5 5.9 0.9 2.4 -0.3 0.0 -2.1 0.4 1.7 -2.4
Standing height 0.5 5.0 13.3 -0.3 2.9 -3.0 0.0 -2.5 -1.8 0.4 -3.6
Length of working week for main job 2.5 2.8 6.6 -1.6 -1.2 -1.9 0.0 1.4 -2.5 -2.6 -0.5
Exposure to tobacco smoke at home 1.2 1.3 3.1 0.6 -0.7 1.7 0.0 1.8 0.8 -0.4 1.7
Breastfed as a baby 2.5 3.1 8.2 0.0 1.7 -2.9 0.0 -0.4 -2.6 -1.6 -2.1
Tense / ‘highly strung’ 0.6 1.0 3.6 0.8 1.3 -0.5 0.0 -1.2 -0.4 0.3 -1.9
Seen doctor (GP) for nerves, anxiety, tension or depression 1.3 2.0 5.2 1.0 1.7 2.1 0.0 -0.7 2.3 1.2 0.9
Hair/balding pattern: Pattern 4 1.0 2.5 6.8 1.2 1.3 0.7 0.0 -2.6 0.4 1.9 -2.5
Birth weight of first child 0.4 0.7 1.8 -0.4 1.4 -0.8 0.0 -1.0 -0.8 0.0 -1.1
Peak expiratory flow (PEF) 0.5 1.3 3.4 -1.1 1.8 -1.4 0.0 -0.4 -1.3 -0.5 -1.2
Pulse wave reflection index 0.4 0.4 1.1 -1.1 -0.4 -0.9 0.0 -0.3 -0.8 0.0 -0.8
Ever highly irritable/argumentative for 2 days 0.5 0.6 1.1 1.1 -0.8 0.8 0.0 -0.8 1.1 0.9 0.2
Loud music exposure frequency 0.7 0.7 1.9 -1.4 -0.5 -0.3 0.0 1.2 -0.9 -1.0 0.3
Qualifications: O levels/GCSEs or equivalent 0.1 0.1 0.8 0.0 -0.9 -0.4 0.0 -0.0 0.1 0.4 0.1
Mouth/teeth dental problems: Bleeding gums 0.5 0.6 1.8 1.3 -0.4 1.3 0.0 0.2 1.0 0.4 0.1
Blood clot in the leg (DVT) 0.7 0.9 5.3 1.0 -2.3 -0.2 0.0 -0.8 0.0 0.4 -0.4
Medication: Paracetamol 0.7 1.1 2.4 0.9 -0.2 1.2 0.0 -1.0 1.4 1.5 1.1
Headache pain in last month 0.2 0.4 1.0 -0.4 0.7 0.4 0.0 1.0 0.1 -0.7 0.9
Medication for cholesterol, blood pressure or diabetes 0.5 0.8 2.1 -0.1 -1.1 -1.5 0.0 -0.6 -1.2 -0.2 -1.2
Glaucoma (self-reported) 2.1 2.4 6.7 -1.2 2.6 -2.0 0.0 0.1 -1.6 -1.3 -1.8
Gout (self-reported) 0.5 0.6 3.5 0.2 -1.9 -1.0 0.0 -0.2 -0.5 0.2 -0.5
Hypothyroidism/myxoedema (self-reported) 0.5 1.0 4.0 0.0 1.2 -0.9 0.0 -0.9 -0.5 0.8 -2.0
Medication: Amlodipine 1.7 2.4 7.1 -1.8 0.9 0.8 0.0 2.7 -0.2 -1.9 2.0
Medication: Ventolin 100micrograms inhaler 1.6 2.0 4.9 -1.6 -0.5 -1.7 0.0 1.4 -1.8 -2.2 -0.1
Birth weight 0.8 1.8 4.7 0.5 1.5 -2.2 0.0 -1.4 -1.8 -0.3 -1.5
Chronic bronchitis/emphysema (mother) 1.2 1.4 2.9 1.3 -1.2 1.4 0.0 -0.8 1.5 1.7 -0.1
High blood pressure (siblings) 1.2 1.7 4.0 -1.8 1.2 -0.4 0.0 2.0 -1.0 -1.8 0.7
Forced vital capacity (FVC), Best measure 0.9 3.1 9.2 -0.1 1.5 -3.0 0.0 -1.4 -2.0 -0.6 -2.6
Body fat percentage 1.4 5.5 13.8 2.3 -1.7 3.7 0.0 0.6 3.4 1.9 2.6
Leg fat percentage (right) 1.6 5.9 16.6 2.5 -1.6 4.1 0.0 0.7 3.5 1.7 2.4
Arm fat-free mass (right) 0.3 1.6 3.0 1.1 1.7 0.9 0.0 -1.5 1.1 1.7 -1.2
Exposure to tobacco smoke outside home 1.7 2.2 7.4 -1.0 -1.3 1.5 0.0 2.7 0.8 -0.7 2.0
Comparative body size at age 10 0.5 1.2 4.9 2.2 1.4 -0.3 0.0 -1.1 -0.4 0.3 -1.3
Number of full brothers 1.1 1.4 3.6 -1.3 -0.2 -1.1 0.0 1.1 -1.8 -1.9 0.3
Worry too long after embarrassment 0.3 0.4 0.8 -0.6 -0.6 -0.9 0.0 0.8 -0.7 -0.9 0.1
Seen a psychiatrist for nerves, anxiety, tension or depression 1.3 1.7 4.5 1.1 -0.1 2.0 0.0 -0.7 2.1 1.5 1.0
Wheeze or whistling in the chest in last year 0.5 0.9 4.0 2.0 -1.4 -0.6 0.0 -0.7 -0.1 0.4 -0.6
Number of children fathered 0.7 0.8 3.1 0.1 1.2 -0.4 0.0 -1.3 0.1 0.6 -1.8
Reason for reducing amount of alcohol drunk: Health precaution 0.8 1.0 3.1 -0.5 -1.2 -0.5 0.0 1.4 -0.8 -1.8 -0.2
Age at first live birth 3.1 5.6 12.5 -2.9 0.7 -3.3 0.0 0.8 -3.5 -2.6 -2.2
Pulse wave peak to peak time 0.5 0.6 3.3 0.0 1.8 -0.5 0.0 0.3 -0.7 -0.6 -0.0
Health satisfaction 1.2 1.6 2.7 1.5 1.0 1.4 0.0 -1.5 1.6 1.6 -0.5
Shortness of breath walking on level ground 0.0 0.0 0.1 0.1 0.2 0.2 0.0 -0.3 0.2 0.2 0.3
Qualifications: College or University degree 1.6 5.0 12.3 -2.5 0.3 -3.2 0.0 0.4 -3.5 -1.8 -2.7
Eye problems/disorders: None of the above 0.8 0.9 2.9 1.7 0.0 1.3 0.0 -0.3 1.0 1.1 0.2
Mouth/teeth dental problems: Loose teeth 0.3 0.4 1.4 0.3 -1.2 -0.4 0.0 0.4 -0.7 -0.8 0.3
Emphysema/chronic bronchitis 1.2 1.3 4.8 -0.7 -2.2 0.2 0.0 1.4 -0.3 -0.7 1.6
Medication for pain relief, constipation, heartburn 0.5 0.8 2.6 -0.5 1.2 -1.2 0.0 -0.2 -0.5 -0.6 -1.6
Neck or shoulder pain in last month 0.4 0.6 2.7 0.3 -1.7 -1.0 0.0 -0.5 -0.5 0.2 -0.6
Medication: Blood pressure 1.1 1.9 5.5 0.2 0.8 2.3 0.0 1.5 1.8 -0.1 1.9
Angina (self-reported) 0.8 1.1 2.5 -0.0 -1.3 1.2 0.0 1.5 0.9 -0.5 1.6
Migraine (self-reported) 0.2 0.2 0.5 0.2 -0.7 -0.3 0.0 0.5 -0.7 -0.6 0.3
Medication: Ibuprofen 0.6 0.8 1.6 1.3 -0.8 1.0 0.0 -0.3 0.9 0.9 1.1
Medication: Allopurinol 0.1 0.1 0.5 -0.2 -0.1 -0.7 0.0 -0.0 -0.5 0.1 -0.3
Medication: Omeprazole 0.2 0.2 0.7 0.9 -0.1 0.6 0.0 0.1 0.7 0.3 0.2
Medication: Seretide 50 evohaler 0.6 0.7 1.4 0.6 -1.0 0.8 0.0 -0.2 0.9 0.9 1.2
Mean time to correctly identify matches 0.2 0.4 1.0 0.3 -0.3 0.3 0.0 -0.8 0.9 1.0 -0.4
Heart disease (mother) 0.8 1.0 3.2 1.1 -0.6 1.8 0.0 0.3 1.5 0.5 1.0
Reproduciblity of spirometry measurement using ERS/ATS criteria 1.0 1.2 4.0 1.4 -0.0 -1.0 0.0 -2.0 -0.3 0.8 -1.3
Whole body fat mass 1.1 4.8 11.8 2.5 -0.9 3.4 0.0 -0.2 3.3 2.3 1.8
Leg fat mass (right) 1.4 5.4 13.6 2.8 -0.9 3.7 0.0 -0.3 3.5 2.4 1.7
Arm predicted mass (right) 0.3 1.8 3.7 1.1 1.7 1.0 0.0 -1.6 1.3 1.9 -1.1
Pulse rate, automated reading 1.1 3.6 10.7 0.8 -0.1 3.3 0.0 -0.3 3.3 2.1 1.5
Alcohol intake frequency. 0.4 0.9 2.3 -0.7 -0.7 -0.2 0.0 1.3 -0.3 -1.5 1.5
Comparative height size at age 10 0.3 1.7 3.5 0.1 1.9 -1.9 0.0 -1.1 -1.4 0.2 -1.8
Number of full sisters 0.1 0.1 0.3 -0.4 0.6 -0.2 0.0 -0.3 -0.1 -0.4 -0.5
Suffer from ‘nerves’ 0.2 0.4 1.1 1.0 0.2 0.7 0.0 0.4 0.5 -0.1 1.0
Overall health rating 1.6 3.5 9.6 1.3 0.5 2.9 0.0 0.3 3.1 1.2 2.5
Chest pain or discomfort 1.9 2.8 7.5 1.9 -0.7 2.7 0.0 0.1 2.3 1.4 1.9
Had major operations 0.6 0.7 3.1 1.8 -0.2 -0.4 0.0 -1.2 -0.3 0.4 -0.7
Age at last live birth 2.8 4.0 9.1 -2.2 1.7 -2.4 0.0 0.9 -3.0 -2.3 -1.9
Family relationship satisfaction 0.9 1.1 3.1 1.5 0.9 0.4 0.0 -1.8 0.4 1.4 0.4
Leg pain on walking 0.6 0.7 2.0 1.4 0.1 0.7 0.0 -0.6 1.4 1.0 0.1
Qualifications: NVQ or HND or HNC or equivalent 0.8 1.0 4.9 0.6 -2.2 0.8 0.0 0.1 1.1 0.7 -0.4
Commuting to job workplace: Car/motor vehicle 0.4 0.5 2.2 -0.4 -1.5 0.5 0.0 -0.3 0.6 0.7 -0.5
Illness, injury, bereavement, stress in last 2 years 0.3 0.3 1.0 -0.1 -1.0 -0.5 0.0 -0.7 -0.4 0.6 -0.6
Medication: Aspirin 0.6 0.8 1.8 -0.4 1.0 1.3 0.0 0.7 1.0 0.3 1.3
Supplements: Vitamin C 0.2 0.3 1.0 0.7 1.0 -0.3 0.0 -0.7 -0.1 0.2 -0.1
Knee pain experienced in last month 0.9 1.5 4.5 2.1 -1.2 0.7 0.0 -0.9 1.1 1.6 0.5
Hypertension (Self-reported) 0.6 1.8 5.7 0.3 -0.2 2.1 0.0 1.4 1.4 0.0 2.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.4 0.5 1.8 -0.5 -0.0 -0.9 0.0 0.4 -1.3 -0.7 -0.8
Illnesses of father: Heart disease 0.3 0.4 1.2 1.1 0.2 0.3 0.0 -1.0 0.5 0.8 -0.0
Illnesses of siblings: Diabetes 0.5 0.6 2.1 -0.3 0.5 -0.3 0.0 1.4 -0.7 -1.0 -1.1
Smoking status: Previous 0.2 0.3 0.8 0.1 0.0 -0.9 0.0 -0.2 -0.7 -0.3 -0.8
Forced expiratory volume in 1-second (FEV1), predicted 0.1 0.3 1.0 -0.3 0.3 -1.0 0.0 -0.1 -0.7 -0.2 -0.6
Whole body fat-free mass 0.3 1.9 4.4 1.0 2.1 0.0 0.0 -1.9 0.6 1.7 -1.8
Leg fat-free mass (right) 0.2 1.1 3.0 0.7 1.7 0.4 0.0 -1.3 0.8 1.5 -0.9
Arm fat percentage (left) 1.4 5.5 13.2 2.5 -1.6 3.6 0.0 0.5 3.4 2.0 2.4
Average weekly red wine intake 0.1 0.2 0.8 0.4 0.0 -0.9 0.0 -0.2 -0.6 -0.1 -0.4
Handedness (chirality/laterality): Left-handed 1.0 1.2 2.6 1.4 1.4 -0.7 0.0 -1.6 -0.6 0.4 -1.6
Mood swings 0.9 1.7 4.9 1.3 0.9 2.2 0.0 0.2 1.7 1.0 1.5
Loneliness, isolation 0.2 0.2 1.1 1.0 -0.7 0.3 0.0 0.0 0.4 0.2 0.3
Long-standing illness, disability or infirmity 0.1 0.2 0.5 0.7 -0.1 -0.4 0.0 -0.7 -0.1 0.2 -0.7
Ever had bowel cancer screening 0.2 0.3 1.3 0.6 -0.0 -0.5 0.0 -0.4 -0.4 0.3 -1.1
Diabetes diagnosed by doctor 0.7 1.1 3.8 -0.6 0.7 1.9 0.0 0.3 1.3 0.6 1.4
Ever had stillbirth, spontaneous miscarriage or termination 0.3 0.3 1.7 -0.4 0.3 -0.6 0.0 -0.5 -0.3 0.1 -1.3
Friendships satisfaction 1.0 1.2 2.3 1.5 -1.2 1.0 0.0 -0.8 0.9 1.3 1.3
Qualifications: nursing, teaching 0.6 0.9 2.4 -0.3 -0.9 -1.5 0.0 0.7 -1.2 -1.4 -0.7
Commuting to job workplace: Walk 0.3 0.3 1.5 0.1 0.5 0.3 0.0 0.4 0.7 0.2 1.2
Eye problems/disorders: Cataract 0.4 0.5 1.3 -1.0 -0.8 0.4 0.0 1.2 0.2 -0.4 0.9
Mouth/teeth dental problems: Mouth ulcers 0.6 1.0 2.9 -0.9 1.0 -1.7 0.0 -0.1 -1.5 -1.0 -0.6
Medication for cholesterol 0.6 0.9 2.9 -0.4 0.6 -1.7 0.0 -0.2 -1.5 -0.7 -1.1
Medication: Laxatives (e.g. Dulcolax, Senokot) 1.2 1.4 7.8 0.6 -2.8 -0.2 0.0 -1.2 0.3 0.8 -0.8
Back pain experienced in last month 0.6 0.9 4.5 0.9 -0.2 -1.1 0.0 -2.1 -0.2 0.9 -0.0
Mineral and other dietary supplements 0.7 0.9 2.5 0.6 0.9 1.6 0.0 0.2 1.4 0.3 1.4
Breast cancer (self-reported) 1.5 1.8 5.8 -1.6 -0.6 -0.1 0.0 2.4 -0.7 -1.8 1.2
Asthma (self-reported) 0.3 0.5 2.0 0.3 0.1 -0.9 0.0 0.0 -0.9 -0.5 -1.4
Osteoporosis (self-reported) 0.6 0.8 2.1 0.3 -0.1 1.4 0.0 0.1 1.3 0.6 1.4
Osteoarthritis (self-reported) 0.0 0.0 0.2 0.4 0.2 -0.3 0.0 0.0 -0.1 0.1 0.2
Medication: Aspirin 0.4 0.5 1.3 -0.0 0.5 1.1 0.0 0.3 1.0 0.6 0.9
Medication: Gliclazide 1.3 1.4 5.5 -0.0 -0.7 2.4 0.0 0.3 1.6 1.1 1.2
Illnesses of father: None of the above (group 1) 1.4 1.7 4.3 2.1 -0.0 0.1 0.0 -1.9 1.0 1.9 -1.0
Smoking status: Current 0.8 1.3 3.9 0.7 -0.6 1.2 0.0 -0.9 1.3 1.4 2.0
Forced expiratory volume in 1-second (FEV1), predicted percentage 1.0 2.1 6.0 0.4 1.1 -2.3 0.0 -1.4 -1.5 -0.3 -2.4
Whole body water mass 0.3 2.0 4.5 1.0 2.1 0.1 0.0 -1.9 0.7 1.8 -1.8
Leg predicted mass (right) 0.2 1.1 2.9 0.7 1.7 0.3 0.0 -1.3 0.7 1.4 -1.0
Arm fat mass (left) 1.1 4.6 11.6 2.4 -0.7 3.4 0.0 -0.0 3.3 2.3 1.8
Number of self-reported non-cancer illnesses 0.4 0.6 1.6 1.0 -0.4 0.3 0.0 -1.2 0.5 1.3 -0.7
Average weekly champagne plus white wine intake 0.7 1.0 3.4 -0.5 1.4 -0.4 0.0 -1.3 -0.7 0.2 -1.8
Miserableness 1.2 2.0 4.7 2.0 -1.0 2.2 0.0 0.5 1.8 1.0 1.4
Guilty feelings 0.9 1.3 4.3 2.1 0.3 1.0 0.0 -1.0 1.2 1.4 -0.8
Wears glasses or contact lenses 0.3 0.4 2.1 -0.2 0.3 -0.3 0.0 -0.7 -0.0 0.5 -1.5
Ever taken oral contraceptive pill 1.0 1.1 3.8 -0.3 0.6 1.6 0.0 0.8 1.1 -0.2 2.0
Hearing aid user 1.3 1.4 3.9 -0.6 0.4 -1.9 0.0 -1.2 -1.4 -0.0 -2.0
Mother’s age at death 2.4 3.0 8.3 0.7 2.7 -1.8 0.0 -2.0 -0.8 0.7 -2.9
Financial situation satisfaction 0.7 0.9 2.5 1.6 -0.2 1.0 0.0 -1.0 1.1 1.1 0.1
Tinnitus: Yes, now most or all of the time 1.6 1.9 3.9 -1.9 1.1 -1.2 0.0 1.5 -1.6 -2.0 0.1
Commuting to job workplace: Public transport 0.3 0.4 1.5 -0.6 0.9 -0.1 0.0 0.5 0.1 -0.2 1.2
Eye problems/disorders: Glaucoma 2.5 2.9 9.7 -0.7 3.1 -2.1 0.0 -0.7 -1.6 -0.7 -2.3
Medication: Blood pressure 0.8 1.6 4.2 -0.3 0.8 1.9 0.0 1.6 1.2 -0.4 2.1
Pain type(s) experienced in last month: Hip pain 0.4 0.5 1.4 1.1 -1.2 -0.5 0.0 -1.0 0.1 0.3 -0.3
Supplements: Fish oil (including cod liver oil) 0.9 1.1 3.2 -1.0 -0.2 -1.8 0.0 0.7 -1.7 -1.1 -0.2
High cholesterol (Self-reported) 0.5 0.9 4.0 0.5 2.0 0.4 0.0 -1.3 0.5 0.8 -0.3
Medication: Bendroflumethiazide 0.3 0.5 1.3 -0.8 -0.4 -0.2 0.0 1.1 -0.4 -1.0 0.7
Medication: Paracetamol 2.2 3.4 7.2 2.0 0.0 2.1 0.0 -1.9 2.5 2.7 1.2
Medication: Lisinopril 0.8 1.1 3.3 0.0 1.2 1.8 0.0 -0.2 1.5 0.9 0.9
Medication: Atorvastatin 0.0 0.1 0.2 -0.0 0.2 -0.3 0.0 -0.1 -0.3 0.4 -0.4
Illnesses of father: High blood pressure 1.7 2.1 5.3 -2.3 1.5 -0.4 0.0 1.8 -1.3 -1.8 0.8
Alcohol drinker status: Never 1.9 2.3 7.6 -1.5 0.4 -1.0 0.0 2.2 -1.6 -2.7 -0.1
Ever smoked 0.3 0.6 2.6 0.4 0.4 -0.5 0.0 -1.6 -0.2 0.8 -0.9
Basal metabolic rate 0.3 1.6 3.3 1.2 1.7 0.6 0.0 -1.6 1.1 1.8 -1.1
Leg fat percentage (left) 1.8 6.4 17.6 2.5 -1.9 4.2 0.0 0.7 3.6 1.9 2.6
Arm fat-free mass (left) 0.2 1.2 2.7 0.8 1.6 0.6 0.0 -1.2 0.9 1.5 -1.2
Number of operations (self-reported) 0.3 0.4 1.6 1.3 0.5 0.1 0.0 -0.7 0.7 0.5 0.1
Average weekly beer plus cider intake 0.1 0.1 0.9 0.2 -0.0 0.0 0.0 0.1 -0.0 -0.0 0.9
Irritability 0.3 0.4 1.5 -0.6 0.4 0.3 0.0 1.2 0.1 -0.6 1.0
Risk taking 0.3 0.4 1.1 -0.6 -0.9 -0.8 0.0 1.1 -0.6 -0.4 -0.1
Ever had prostate specific antigen (PSA) test 0.2 0.3 0.8 0.7 0.2 -0.0 0.0 -0.9 0.3 0.6 -0.4
Fractured/broken bones in last 5 years 0.5 0.6 1.5 1.1 -0.6 0.2 0.0 -0.8 0.7 1.2 1.1
Age started oral contraceptive pill 0.1 0.2 0.3 -0.4 -0.4 -0.4 0.0 0.2 -0.6 -0.3 -0.6
Diastolic blood pressure, automated reading 0.6 1.7 5.4 -0.2 -0.3 2.2 0.0 0.6 1.7 0.3 2.3
Ever depressed for a whole week 0.7 0.8 2.3 1.5 -0.2 0.4 0.0 -1.5 0.8 0.8 -0.7
Unable to work because of sickness or disability 1.1 1.4 4.0 0.9 0.2 1.8 0.0 0.9 1.6 0.1 2.0
Commuting to job workplace: Cycle 1.0 1.2 3.2 0.5 1.7 -1.5 0.0 -0.3 -1.8 -0.7 0.0
Myopia 0.3 0.5 2.0 1.4 0.5 0.5 0.0 -0.6 0.9 0.4 -0.0
Vascular/heart problems diagnosed by doctor 1.0 2.7 8.5 -0.4 -0.1 -2.6 0.0 -1.6 -1.9 0.0 -2.9
Cholesterol lowering medication 0.3 0.5 1.5 -0.2 0.8 1.2 0.0 0.1 1.0 0.5 0.5
Medication: Omeprazole (e.g. Zanprol) 0.3 0.3 1.0 0.7 -1.0 0.6 0.0 0.5 0.7 0.3 0.4
Pain experienced in last month 0.3 0.4 1.7 -1.3 0.7 -0.4 0.0 0.2 -0.5 -0.5 -0.7
Supplements: Calcium 0.4 0.4 1.6 -0.5 0.6 -0.7 0.0 -0.8 -0.2 -0.2 -1.3
Basal cell carcinoma (self-reported) 0.5 0.6 1.4 1.1 1.2 0.4 0.0 -0.8 0.8 1.0 -0.3
Heart attack/myocardial infarction (self-reported) 0.4 0.6 1.1 0.3 -1.1 1.1 0.0 0.8 0.8 0.2 1.0
Deep venous thrombosis (DVT) (self-reported) 0.9 1.1 4.9 1.5 -2.2 0.3 0.0 -0.9 0.4 0.8 -0.2
Heart disease (siblings) 1.7 2.1 4.8 -1.8 -1.1 -0.6 0.0 2.2 -1.0 -2.1 1.4
Alcohol drinker status: Previous 0.5 0.6 1.5 -0.9 -0.3 -0.7 0.0 0.8 -0.4 -1.2 1.0
Pack years of smoking 0.1 0.1 0.5 0.3 -0.7 -0.2 0.0 0.4 0.0 0.2 0.6
Impedance of whole body 0.3 1.5 3.2 -0.9 -1.8 -0.9 0.0 1.4 -1.3 -1.7 1.0
Leg fat mass (left) 1.4 5.4 13.5 2.6 -1.0 3.7 0.0 -0.2 3.5 2.4 1.9
Arm predicted mass (left) 0.3 1.4 2.7 1.0 1.6 0.6 0.0 -1.5 0.9 1.6 -1.4