Best TWAS P=2.99e-16 · Best GWAS P=2.8e-16 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Whole Blood | NLRC5 | 0.18 | 0.09 | enet | 17 | 0.12 | 6.9e-11 | 8.2 | 6.8 | 1.3e-11 | 0.84 | 0 | 1.00 | FALSE |
| 2 | NTR | Blood | NLRC5 | 0.05 | 0.03 | lasso | 3 | 0.03 | 5.1e-09 | 8.2 | 8.2 | 3.0e-16 | 0.96 | 0 | 1.00 | TRUE |
| 3 | YFS | Blood | NLRC5 | 0.22 | 0.07 | bslmm | 564 | 0.17 | 9.0e-52 | 8.2 | 5.6 | 1.9e-08 | 0.56 | 0 | 1.00 | FALSE |
| 4 | The Cancer Genome Atlas | Colon Adenocarcinoma | CETP | 0.11 | 0.03 | blup | 90 | 0.05 | 1.2e-03 | 8.2 | 6.0 | 2.2e-09 | 0.56 | 0 | 0.97 | FALSE |