Best TWAS P=2.2e-09 · Best GWAS P=9.6e-09 conditioned to 0.349
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Thyroid | NOB1 | 0.03 | 0.01 | enet | 6 | 0.02 | 0.0077 | 4.2 | -5.8 | 5.2e-09 | -0.77 | 0.08 | 0.74 | FALSE |
| 2 | GTEx | Thyroid | CTD-2033A16.3 | 0.03 | 0.02 | enet | 7 | 0.02 | 0.0067 | 5.4 | -6.0 | 2.2e-09 | -0.89 | 0.03 | 0.90 | TRUE |
| 3 | The Cancer Genome Atlas | Breast Invasive Carcinoma | NQO1 | 0.02 | 0.01 | blup | 39 | 0.01 | 0.0043 | 5.5 | 5.5 | 3.3e-08 | 0.86 | 0.01 | 0.86 | FALSE |
| 4 | The Cancer Genome Atlas | Colon Adenocarcinoma | NQO1 | 0.06 | 0.04 | lasso | 3 | 0.01 | 0.0527 | 5.5 | 5.5 | 4.4e-08 | 0.99 | 0.01 | 0.74 | FALSE |