Best TWAS P=1.21e-10 · Best GWAS P=2.2e-34 conditioned to 1.44e-25
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | COTL1 | 0.23 | 0.02 | lasso | 7 | 0.03 | 2.3e-03 | 5.0 | -6.4 | 1.2e-10 | -0.45 | 0.16 | 0.44 | TRUE |
| 2 | GTEx | Artery Tibial | COTL1 | 0.23 | 0.13 | lasso | 4 | 0.13 | 2.7e-10 | 6.2 | -6.0 | 2.5e-09 | -0.27 | 1.00 | 0.00 | FALSE |
| 3 | METSIM | Adipose | COTL1 | 0.13 | 0.13 | enet | 16 | 0.13 | 1.4e-18 | 5.4 | -5.4 | 7.0e-08 | -0.27 | 1.00 | 0.00 | FALSE |
| 4 | The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | COTL1 | 0.12 | 0.00 | blup | 135 | 0.02 | 7.8e-03 | 0.1 | -5.6 | 2.3e-08 | -0.31 | 0.04 | 0.08 | FALSE |