[Hub]/) : Traits : Blood White Count : ← →

chr16:89,013,848-90,172,696

Best TWAS P=1.5e-13 · Best GWAS P=3.94e-10 conditioned to 0.672

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	CDK10	0.27	0.14	lasso	9	0.21	6.9e-25	-6.2	5.2	2.7e-07	-0.83	0.00	1.00	FALSE
2	GTEx	Adipose Subcutaneous	DEF8	0.11	0.02	enet	16	0.06	1.3e-05	-3.6	-6.1	8.9e-10	0.57	0.02	0.95	FALSE
3	GTEx	Adipose Visceral Omentum	CDK10	0.43	0.19	lasso	6	0.32	3.6e-17	-6.2	6.3	2.7e-10	-0.82	0.00	1.00	FALSE
4	GTEx	Artery Tibial	CDK10	0.29	0.10	enet	15	0.22	2.4e-17	-6.3	6.1	1.1e-09	-0.77	0.00	1.00	FALSE
5	GTEx	Brain Cerebellum	CDK10	0.44	0.12	enet	23	0.28	5.1e-09	-6.2	5.8	7.1e-09	-0.80	0.00	1.00	FALSE
6	GTEx	Colon Transverse	CDK10	0.34	0.15	lasso	5	0.16	4.2e-08	-4.2	5.8	7.1e-09	-0.64	0.07	0.92	FALSE
7	GTEx	Esophagus Gastroesophageal Junction	CDK10	0.38	0.28	lasso	4	0.29	5.6e-11	-6.3	6.4	1.6e-10	-0.92	0.00	1.00	FALSE
8	GTEx	Esophagus Mucosa	CDK10	0.36	0.15	lasso	6	0.23	1.9e-15	-6.2	6.7	1.9e-11	-0.88	0.00	1.00	FALSE
9	GTEx	Esophagus Muscularis	VPS9D1	0.18	0.02	lasso	3	0.03	4.0e-03	-5.4	-6.3	2.5e-10	0.50	0.01	0.94	FALSE
10	GTEx	Esophagus Muscularis	CDK10	0.24	0.11	enet	19	0.14	4.3e-09	-6.2	5.7	1.1e-08	-0.83	0.00	1.00	FALSE
11	GTEx	Heart Atrial Appendage	CDK10	0.26	0.07	lasso	3	0.13	1.4e-06	2.2	5.8	5.8e-09	-0.72	0.01	0.98	FALSE
12	GTEx	Lung	CDK10	0.25	0.18	lasso	7	0.19	1.0e-14	-4.2	5.7	1.1e-08	-0.60	0.94	0.05	FALSE
13	GTEx	Muscle Skeletal	CDK10	0.17	0.12	lasso	6	0.10	9.2e-10	-6.2	6.1	9.1e-10	-0.98	0.00	1.00	FALSE
14	GTEx	Nerve Tibial	CDK10	0.42	0.28	enet	16	0.35	1.2e-25	-3.9	5.8	9.0e-09	-0.69	0.67	0.33	FALSE
15	GTEx	Ovary	CDK10	0.45	0.11	lasso	8	0.25	6.8e-07	-6.2	6.1	9.0e-10	-0.77	0.00	0.98	FALSE
16	GTEx	Prostate	CDK10	0.41	0.16	lasso	6	0.24	1.0e-06	-6.2	6.6	3.2e-11	-0.90	0.00	0.98	FALSE
17	GTEx	Skin Not Sun Exposed Suprapubic	CHMP1A	0.25	0.01	enet	21	0.08	5.3e-05	-3.5	-5.5	2.8e-08	0.53	0.14	0.73	FALSE
18	GTEx	Skin Not Sun Exposed Suprapubic	CDK10	0.27	0.19	lasso	9	0.28	1.2e-15	-3.9	6.2	4.3e-10	-0.75	0.01	0.99	FALSE
19	GTEx	Skin Sun Exposed Lower leg	CDK10	0.30	0.18	enet	18	0.29	3.0e-24	-6.2	6.0	2.0e-09	-0.79	0.00	1.00	FALSE
20	GTEx	Skin Sun Exposed Lower leg	VPS9D1-AS1	0.18	0.04	lasso	5	0.06	1.2e-05	-5.6	-6.8	1.4e-11	0.74	0.01	0.99	FALSE
21	GTEx	Small Intestine Terminal Ileum	VPS9D1	0.34	0.04	enet	11	0.11	2.4e-03	-6.2	-7.4	1.5e-13	0.81	0.01	0.95	TRUE
22	GTEx	Spleen	VPS9D1	0.40	0.26	lasso	5	0.20	5.6e-06	-5.4	-5.3	1.1e-07	0.42	0.09	0.69	FALSE
23	GTEx	Stomach	CDK10	0.35	0.12	enet	12	0.22	6.4e-11	-6.3	5.5	4.1e-08	-0.76	0.00	1.00	FALSE
24	GTEx	Testis	CDK10	0.28	0.14	lasso	6	0.24	4.1e-11	-4.1	6.3	2.2e-10	-0.74	0.01	0.99	FALSE
25	GTEx	Whole Blood	MC1R	0.08	0.00	enet	18	0.00	5.5e-01	-4.3	6.8	1.2e-11	-0.32	0.05	0.12	FALSE
26	METSIM	Adipose	CDK10	0.23	0.14	lasso	12	0.21	7.9e-31	-6.2	7.0	3.1e-12	-0.84	0.00	1.00	FALSE
27	METSIM	Adipose	RP11-368I7.4	0.04	0.03	enet	12	0.02	2.2e-04	-6.2	-5.5	5.0e-08	0.83	0.00	1.00	FALSE
28	NTR	Blood	FANCA	0.06	0.04	lasso	2	0.04	3.9e-13	-5.6	5.5	5.1e-08	-0.42	0.11	0.89	FALSE
29	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	SPIRE2	0.10	0.05	lasso	4	0.04	1.5e-05	-5.6	5.8	5.3e-09	-0.40	0.09	0.77	FALSE
30	The Cancer Genome Atlas	Brain Lower Grade Glioma	CDK10	0.15	0.03	blup	42	0.08	3.7e-09	-3.9	6.6	3.2e-11	-0.47	0.00	0.54	FALSE
31	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	CDK10	0.06	0.00	blup	43	0.02	2.2e-03	2.0	6.4	2.0e-10	-0.47	0.00	0.00	FALSE
32	The Cancer Genome Atlas	Thyroid Carcinoma	CDK10	0.06	0.04	blup	43	0.04	8.9e-05	-3.9	6.2	4.7e-10	-0.43	0.00	0.67	FALSE
33	The Cancer Genome Atlas	Thyroid Carcinoma	SPIRE2	0.12	0.06	enet	10	0.08	8.5e-08	4.1	5.2	2.4e-07	-0.29	0.71	0.09	FALSE