[Hub]/) : Traits : Blood White Count : ← →

chr19:51,029,602-52,445,386

Best TWAS P=1.18e-12 · Best GWAS P=1.51e-33 conditioned to 7.09e-23

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
9	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	CD33	0.05	0.06	lasso	1	0.06	5.1e-07	7.1	7.1	1.2e-12	-0.58	0.94	0.02	TRUE
14	The Cancer Genome Atlas	Testicular Germ Cell Tumors	SIGLEC14	0.39	0.07	lasso	6	0.07	2.1e-03	4.3	-6.0	2.4e-09	-0.01	0.01	0.33	TRUE
1	GTEx	Whole Blood	CD33	0.17	0.05	lasso	3	0.01	2.2e-02	7.0	7.0	2.3e-12	-0.58	0.15	0.42	FALSE
3	The Cancer Genome Atlas	Breast Invasive Carcinoma	CD33	0.09	0.08	lasso	2	0.09	1.0e-17	7.0	6.9	3.9e-12	-0.58	1.00	0.00	FALSE
6	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	CD33	0.10	0.01	enet	18	0.06	2.0e-04	7.0	6.1	1.1e-09	-0.55	0.08	0.24	FALSE
12	The Cancer Genome Atlas	Prostate Adenocarcinoma	SIGLEC14	0.17	0.05	lasso	4	0.10	6.3e-11	-4.3	-5.9	4.1e-09	0.03	0.11	0.79	FALSE
8	The Cancer Genome Atlas	Lung Adenocarcinoma	SIGLEC14	0.33	0.11	enet	20	0.12	6.6e-14	4.3	-5.7	1.6e-08	-0.02	0.09	0.83	FALSE
2	YFS	Blood	CD33	0.16	0.09	enet	42	0.12	1.2e-37	7.1	5.6	1.7e-08	-0.44	1.00	0.00	FALSE
7	The Cancer Genome Atlas	Brain Lower Grade Glioma	SIGLEC5	0.12	0.00	lasso	4	0.02	3.5e-03	4.3	-5.5	4.8e-08	-0.02	0.02	0.48	FALSE
10	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	SIGLEC14	0.34	0.16	enet	11	0.18	1.4e-20	4.3	-5.4	6.4e-08	-0.02	0.09	0.83	FALSE
5	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	SIGLEC14	0.23	0.08	enet	12	0.10	1.6e-11	4.0	-5.4	7.5e-08	0.00	0.21	0.61	FALSE
13	The Cancer Genome Atlas	Stomach Adenocarcinoma	SIGLEC14	0.28	0.14	enet	14	0.17	1.4e-12	4.3	-5.3	8.8e-08	-0.01	0.10	0.83	FALSE
11	The Cancer Genome Atlas	Prostate Adenocarcinoma	CD33	0.11	0.08	blup	55	0.09	5.2e-10	7.1	5.3	1.0e-07	-0.34	0.88	0.12	FALSE
4	The Cancer Genome Atlas	Breast Invasive Carcinoma	SIGLEC14	0.30	0.15	enet	18	0.18	1.4e-34	4.3	-5.2	1.9e-07	-0.02	0.09	0.83	FALSE
15	The Cancer Genome Atlas	Thyroid Carcinoma	SIGLEC14	0.17	0.04	enet	16	0.08	4.6e-08	4.3	-5.2	2.6e-07	0.01	0.06	0.88	FALSE